CA2384388A1 - Bibliotheque amelioree d'affichage de phages de fragments de vh humain et procedes de production des memes - Google Patents

Bibliotheque amelioree d'affichage de phages de fragments de vh humain et procedes de production des memes Download PDF

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Publication number
CA2384388A1
CA2384388A1 CA002384388A CA2384388A CA2384388A1 CA 2384388 A1 CA2384388 A1 CA 2384388A1 CA 002384388 A CA002384388 A CA 002384388A CA 2384388 A CA2384388 A CA 2384388A CA 2384388 A1 CA2384388 A1 CA 2384388A1
Authority
CA
Canada
Prior art keywords
library
parental
amino acids
binding
fragment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002384388A
Other languages
English (en)
Inventor
Howard Kaplan (Deceased)
Jocelyn Entwistle
Jamshid Tanha
Saran Narang
Michael Dan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
National Research Council of Canada
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CA 2282179 external-priority patent/CA2282179A1/fr
Application filed by Individual filed Critical Individual
Priority to CA002384388A priority Critical patent/CA2384388A1/fr
Priority claimed from PCT/CA2000/001027 external-priority patent/WO2001018058A2/fr
Publication of CA2384388A1 publication Critical patent/CA2384388A1/fr
Abandoned legal-status Critical Current

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  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

L'invention concerne des bibliothèques d'affichage de phages dans lesquelles la population de phages recombinants présente plusieurs fragments de liaison potentiels possédant des caractéristiques préférées de solubilité et/ou d'interaction intermoléculaire. L'invention concerne également des procédés de dépolarisation de bibliothèques d'affichage, afin de produire des variants, qui approchent au plus près des caractéristiques préférées du fragment de liaison parent.
CA002384388A 1999-09-07 2000-09-07 Bibliotheque amelioree d'affichage de phages de fragments de vh humain et procedes de production des memes Abandoned CA2384388A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA002384388A CA2384388A1 (fr) 1999-09-07 2000-09-07 Bibliotheque amelioree d'affichage de phages de fragments de vh humain et procedes de production des memes

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
CA 2282179 CA2282179A1 (fr) 1999-09-07 1999-09-07 Presentoir de librairie a phage ameliore
CA2,282,179 1999-09-07
US16354699P 1999-11-04 1999-11-04
US60/163,546 1999-11-04
CA002384388A CA2384388A1 (fr) 1999-09-07 2000-09-07 Bibliotheque amelioree d'affichage de phages de fragments de vh humain et procedes de production des memes
PCT/CA2000/001027 WO2001018058A2 (fr) 1999-09-07 2000-09-07 Bibliotheque amelioree d'affichage de phages de fragments de vh humain et procedes de production des memes

Publications (1)

Publication Number Publication Date
CA2384388A1 true CA2384388A1 (fr) 2001-03-15

Family

ID=27171036

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002384388A Abandoned CA2384388A1 (fr) 1999-09-07 2000-09-07 Bibliotheque amelioree d'affichage de phages de fragments de vh humain et procedes de production des memes

Country Status (1)

Country Link
CA (1) CA2384388A1 (fr)

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued