CA2379360A1 - Recepteur humain couple a une proteine g - Google Patents
Recepteur humain couple a une proteine g Download PDFInfo
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- CA2379360A1 CA2379360A1 CA002379360A CA2379360A CA2379360A1 CA 2379360 A1 CA2379360 A1 CA 2379360A1 CA 002379360 A CA002379360 A CA 002379360A CA 2379360 A CA2379360 A CA 2379360A CA 2379360 A1 CA2379360 A1 CA 2379360A1
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- igs1
- polypeptide
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Abstract
La présente invention concerne des polynucléotides nouvellement identifiés, les polypeptides codés par lesdits polynucléotides, l'utilisation de ces polynucléotides et polypeptides et leur production. En particulier, les polynucléotides et polypeptides de la présente invention appartiennent à la famille des récepteurs couplés aux protéines G, que l'on appelle famille IGS1. L'invention concerne également l'inhibition ou l'activation de l'action de ces polynucléotides et polypeptides, un vecteur contenant lesdits polynucléotides, une cellule hôte contenant le vecteur précité ainsi que des animaux transgéniques chez lesquels le gène IGS1 est surexprimé, mal exprimé, sous-exprimé voire supprimé (animaux <= knock-out >=). L'invention concerne enfin une méthode de criblage de composés pouvant avoir une activité d'agoniste ou d'antagoniste vis-à-vis de la famille IGS1 des récepteurs couplés aux protéines G, ainsi que l'utilisation des polypeptides et des polynucléotides IGS1 et des agonistes ou antagonistes de la famille des récepteurs IGS1 dans le traitement des troubles psychiatriques et des dysfonctionnements du système nerveux central.
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP99202326 | 1999-07-15 | ||
| EP99202326.7 | 1999-07-15 | ||
| NL1012611 | 1999-07-15 | ||
| NL1012611 | 1999-07-15 | ||
| PCT/EP2000/006878 WO2001009184A1 (fr) | 1999-07-15 | 2000-07-17 | Recepteur humain couple a une proteine g |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2379360A1 true CA2379360A1 (fr) | 2001-02-08 |
Family
ID=26153341
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002379360A Abandoned CA2379360A1 (fr) | 1999-07-15 | 2000-07-17 | Recepteur humain couple a une proteine g |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP1200474A1 (fr) |
| JP (1) | JP2003508026A (fr) |
| CN (1) | CN1371390A (fr) |
| AU (1) | AU764310B2 (fr) |
| CA (1) | CA2379360A1 (fr) |
| HK (1) | HK1042099A1 (fr) |
| IL (1) | IL146151A0 (fr) |
| WO (1) | WO2001009184A1 (fr) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6555339B1 (en) | 1997-04-14 | 2003-04-29 | Arena Pharmaceuticals, Inc. | Non-endogenous, constitutively activated human protein-coupled receptors |
| US7119190B2 (en) | 1997-04-14 | 2006-10-10 | Arena Pharmaceuticals, Inc. | Endogenous and non-endogenous versions of human G protein-coupled receptors |
| EP1242448A2 (fr) * | 1999-11-17 | 2002-09-25 | Arena Pharmaceuticals, Inc. | Versions endogenes et non-endogenes de recepteurs couples a la proteine g humaine |
| WO2001081410A2 (fr) * | 2000-04-25 | 2001-11-01 | Pharmacia & Upjohn Company | Nouveaux recepteurs couples aux proteines g |
| GB2367295A (en) * | 2000-06-16 | 2002-04-03 | Smithkline Beecham Corp | AXOR69 polypeptides and polynucleotides |
| WO2002059304A1 (fr) * | 2001-01-23 | 2002-08-01 | Takeda Chemical Industries, Ltd. | Nouvelle proteine receptrice couplee a une proteine g et adn correspondant |
| FR2822844B1 (fr) * | 2001-03-27 | 2004-07-16 | Servier Lab | Sequence d'acides nucleiques codant un nouveau recepteur couple aux proteines g et utilisation |
| US6902902B2 (en) | 2001-11-27 | 2005-06-07 | Arena Pharmaceuticals, Inc. | Human G protein-coupled receptors and modulators thereof for the treatment of metabolic-related disorders |
| EP2049262A2 (fr) | 2006-07-19 | 2009-04-22 | Bionanomatrix, Inc. | Réseaux de dispositif de nanobuses: leur préparation et utilisation dans l'analyse macromoléculaire |
| EP2604344A3 (fr) | 2007-03-28 | 2014-07-16 | BioNano Genomics, Inc. | Procédés d'analyse macromoléculaire utilisant des réseaux de nanocanaux |
| JP2011520465A (ja) | 2008-05-19 | 2011-07-21 | ベス・イスラエル・ディーコネス・メディカル・センター，インコーポレイテッド | 新規ｇｐｒ１０１トランスジェニックマウスおよびそれを使用する方法 |
| EP2664677B1 (fr) | 2008-06-30 | 2018-05-30 | BioNano Genomics, Inc. | Procédés pour analyse mono-moléculaire de génome entier |
| CN108467887A (zh) | 2008-11-18 | 2018-08-31 | 生物纳米基因公司 | 多核苷酸作图和测序 |
| CN107460160A (zh) * | 2017-08-23 | 2017-12-12 | 世贸天阶制药（江苏）有限责任公司 | 一种cho细胞无血清培养基 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1996005225A1 (fr) * | 1994-08-10 | 1996-02-22 | Human Genome Sciences, Inc. | Recepteur adrenergique |
| US5817480A (en) * | 1996-11-07 | 1998-10-06 | Incyte Pharmaceuticals | DNA encoding a histamine H2 receptor |
| US6008050A (en) * | 1997-04-02 | 1999-12-28 | Smithkline Beecham Corporation | Human neurotensin receptor type 2 and splice variants thereof |
-
2000
- 2000-07-17 EP EP00945931A patent/EP1200474A1/fr not_active Withdrawn
- 2000-07-17 CN CN00808983A patent/CN1371390A/zh active Pending
- 2000-07-17 JP JP2001513990A patent/JP2003508026A/ja active Pending
- 2000-07-17 CA CA002379360A patent/CA2379360A1/fr not_active Abandoned
- 2000-07-17 IL IL14615100A patent/IL146151A0/xx unknown
- 2000-07-17 AU AU59858/00A patent/AU764310B2/en not_active Ceased
- 2000-07-17 WO PCT/EP2000/006878 patent/WO2001009184A1/fr not_active Application Discontinuation
-
2002
- 2002-05-27 HK HK02103915.4A patent/HK1042099A1/zh unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP1200474A1 (fr) | 2002-05-02 |
| WO2001009184A1 (fr) | 2001-02-08 |
| AU764310B2 (en) | 2003-08-14 |
| JP2003508026A (ja) | 2003-03-04 |
| AU5985800A (en) | 2001-02-19 |
| HK1042099A1 (zh) | 2002-08-02 |
| CN1371390A (zh) | 2002-09-25 |
| IL146151A0 (en) | 2002-07-25 |
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| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| FZDE | Discontinued |