CA2371238A1 - Amino acid sequence evaluation system - Google Patents

Amino acid sequence evaluation system Download PDF

Info

Publication number
CA2371238A1
CA2371238A1 CA002371238A CA2371238A CA2371238A1 CA 2371238 A1 CA2371238 A1 CA 2371238A1 CA 002371238 A CA002371238 A CA 002371238A CA 2371238 A CA2371238 A CA 2371238A CA 2371238 A1 CA2371238 A1 CA 2371238A1
Authority
CA
Canada
Prior art keywords
amino acid
query
acid sequence
motif
score
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002371238A
Other languages
English (en)
French (fr)
Inventor
Stefano Volinia
Hung-Sen Lai
Michael B. Yaffe
German G. Lepar
Lewis C. Cantley
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beth Israel Deaconess Medical Center Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2371238A1 publication Critical patent/CA2371238A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G16B20/30—Detection of binding sites or motifs
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
    • G16B30/10—Sequence alignment; Homology search
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Evolutionary Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medical Informatics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Theoretical Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
CA002371238A 1999-04-23 2000-04-21 Amino acid sequence evaluation system Abandoned CA2371238A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US29837199A 1999-04-23 1999-04-23
US09/298,371 1999-04-23
PCT/US2000/010756 WO2000065358A2 (en) 1999-04-23 2000-04-21 Amino acid sequence evaluation system

Publications (1)

Publication Number Publication Date
CA2371238A1 true CA2371238A1 (en) 2000-11-02

Family

ID=23150210

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002371238A Abandoned CA2371238A1 (en) 1999-04-23 2000-04-21 Amino acid sequence evaluation system

Country Status (5)

Country Link
EP (1) EP1173755A2 (de)
JP (1) JP2002543390A (de)
AU (1) AU4479200A (de)
CA (1) CA2371238A1 (de)
WO (1) WO2000065358A2 (de)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5532167A (en) * 1994-01-07 1996-07-02 Beth Israel Hospital Substrate specificity of protein kinases
US20020068301A1 (en) * 1997-05-28 2002-06-06 Hung-Sen Lai Cyclic peptide libraries and methods of use thereof to identify binding motifs

Also Published As

Publication number Publication date
EP1173755A2 (de) 2002-01-23
WO2000065358A3 (en) 2001-01-11
AU4479200A (en) 2000-11-10
WO2000065358A2 (en) 2000-11-02
JP2002543390A (ja) 2002-12-17

Similar Documents

Publication Publication Date Title
Roberts et al. DOT2: Macromolecular docking with improved biophysical models
Warren et al. Essential considerations for using protein–ligand structures in drug discovery
Attwood The quest to deduce protein function from sequence: the role of pattern databases
Tien et al. Maximum allowed solvent accessibilites of residues in proteins
Rarey et al. A fast flexible docking method using an incremental construction algorithm
Schafferhans et al. Docking ligands onto binding site representations derived from proteins built by homology modelling
Cherfils et al. Protein‐protein recognition analyzed by docking simulation
US6230102B1 (en) Computer system and process for identifying a charge distribution which minimizes electrostatic contribution to binding at binding between a ligand and a molecule in a solvent and uses thereof
De Sancho et al. Integrated prediction of protein folding and unfolding rates from only size and structural class
Skolnick et al. FINDSITE: a combined evolution/structure-based approach to protein function prediction
Malmström et al. Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology
US20070134662A1 (en) Structural interaction fingerprint
Aldeghi et al. Accurate calculation of free energy changes upon amino acid mutation
KR20030059196A (ko) 분리된 아구조 분석을 수행하기 위한 컴퓨터 시스템의조작 방법
Jackson Q-fit: a probabilistic method for docking molecular fragments by sampling low energy conformational space
Verkhivker et al. A mean field model of ligand-protein interactions: implications for the structural assessment of human immunodeficiency virus type 1 protease complexes and receptor-specific binding.
Tosovic et al. Conserved water networks identification for drug design using density clustering approaches on positional and orientational data
Huang et al. Adaptation of a fast Fourier transform‐based docking algorithm for protein design
Vangone et al. Prediction of biomolecular complexes
Nakajima et al. Databases for Protein–Protein Interactions
CA2371238A1 (en) Amino acid sequence evaluation system
JP4688467B2 (ja) 受容体−リガンド安定複合体構造探索方法
Kontoyianni et al. Functional prediction of binding pockets
Li et al. Analysis of sequence–reactivity space for protein–protein interactions
Bianco et al. Reactive Docking: a computational method for high-throughput virtual screenings of reactive species

Legal Events

Date Code Title Description
FZDE Discontinued