CA2366862A1 - Transdermal therapeutic system and process for its production - Google Patents

Transdermal therapeutic system and process for its production Download PDF

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Publication number
CA2366862A1
CA2366862A1 CA002366862A CA2366862A CA2366862A1 CA 2366862 A1 CA2366862 A1 CA 2366862A1 CA 002366862 A CA002366862 A CA 002366862A CA 2366862 A CA2366862 A CA 2366862A CA 2366862 A1 CA2366862 A1 CA 2366862A1
Authority
CA
Canada
Prior art keywords
active agent
therapy system
deposit
production
therapeutic system
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002366862A
Other languages
French (fr)
Other versions
CA2366862C (en
Inventor
Robert-Peter Klein
Reinhold Meconi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
LTS Lohmann Therapie Systeme AG
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19912477A external-priority patent/DE19912477A1/en
Application filed by Individual filed Critical Individual
Publication of CA2366862A1 publication Critical patent/CA2366862A1/en
Application granted granted Critical
Publication of CA2366862C publication Critical patent/CA2366862C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Materials For Medical Uses (AREA)

Abstract

The invention relates to a transdermal therapy system (TTS) which comprises the following essential characteristics: a back layer which faces away from the skin and is impermeable to the active agent, at least one active agent deposit, a matrix which is connected to said active agent deposit and which controls the release of the active agent;
and an adhesive fixing device for fixing the therapy system on the skin. The deposit and/or the matrix also contain support materials consisting of paper. The invention also relates to a method for producing the inventive transdermal therapy system and to the use of the same.
CA002366862A 1999-03-18 2000-03-09 Transdermal therapeutic system and process for its production Expired - Lifetime CA2366862C (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US12495799P 1999-03-18 1999-03-18
US60/124,957 1999-03-18
DE19912477A DE19912477A1 (en) 1999-03-19 1999-03-19 Self-adhesive transdermal therapeutic system for e.g. drug or hormone delivery, comprises an active agent deposit and a connected matrix, including a paper substrate
DE19912477.9 1999-03-19
PCT/EP2000/002042 WO2000056290A1 (en) 1999-03-18 2000-03-09 Transdermal therapy system and method for producing the same

Publications (2)

Publication Number Publication Date
CA2366862A1 true CA2366862A1 (en) 2000-09-28
CA2366862C CA2366862C (en) 2008-05-20

Family

ID=26052471

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002366862A Expired - Lifetime CA2366862C (en) 1999-03-18 2000-03-09 Transdermal therapeutic system and process for its production

Country Status (8)

Country Link
EP (1) EP1161230B1 (en)
KR (1) KR100594666B1 (en)
AT (1) ATE252895T1 (en)
AU (1) AU777992B2 (en)
CA (1) CA2366862C (en)
ES (1) ES2208294T3 (en)
TR (1) TR200102732T2 (en)
WO (1) WO2000056290A1 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8383149B2 (en) 2005-09-23 2013-02-26 Alza Corporation High enhancer-loading polyacrylate formulation for transdermal applications
US9056061B2 (en) 2005-09-23 2015-06-16 Alza Corporation Transdermal nicotine salt delivery system

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ591834A (en) 2008-10-02 2011-12-22 Mylan Inc Method of making a multilayer adhesive laminate
EP2946775A1 (en) * 2014-05-20 2015-11-25 LTS LOHMANN Therapie-Systeme AG Transdermal therapeutic system containing lavender oil

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB845841A (en) * 1957-12-19 1960-08-24 Friedrich Meyer Percutaneous administration of physiologically active agents
JPS55160717A (en) * 1979-06-01 1980-12-13 Toyo Ink Mfg Co Ltd Preparation of application
US4879119A (en) * 1984-02-21 1989-11-07 Yamanouchi Pharmaceutical Co., Ltd. Patch
DE3727214A1 (en) * 1987-08-14 1989-02-23 Lohmann Therapie Syst Lts TAMPON PRINTING DEVICE FOR TRANSMITTING DEFINED QUANTITIES OF PRINTING MEDIUM PER AREA UNIT
DE4230589C1 (en) * 1992-09-12 1994-02-03 Lohmann Therapie Syst Lts Dosing process for volatile or thermolabile substances in liquid form for the production of i.a. flat pharmaceutical forms, in particular for the production of transdermal or dermal therapeutic systems
CA2250025C (en) * 1996-03-25 2006-10-31 Lts Lohmann Therapie-Systeme Gmbh Transdermal therapeutic system with small application-area thickness and great flexibility, and production process
ES2177962T3 (en) * 1996-03-25 2002-12-16 Lohmann Therapie Syst Lts TRANSDERMAL ADMINISTRATION SYSTEM OF REDUCED APPLICATION THICKNESS AND HIGH FLEXIBILITY, AND MANUFACTURING PROCESS OF THE SAME.

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8383149B2 (en) 2005-09-23 2013-02-26 Alza Corporation High enhancer-loading polyacrylate formulation for transdermal applications
US8758808B2 (en) 2005-09-23 2014-06-24 Alza Corporation Method of making a high enhancer-loading polyacrylate formulation for transdermal applications
US9056061B2 (en) 2005-09-23 2015-06-16 Alza Corporation Transdermal nicotine salt delivery system
US9205090B2 (en) 2005-09-23 2015-12-08 Alza Corporation High enhancer-loading polyacrylate formulation for transdermal applications
US9446004B2 (en) 2005-09-23 2016-09-20 Alza Corporation Transdermal nicotine salt delivery system

Also Published As

Publication number Publication date
ATE252895T1 (en) 2003-11-15
AU777992B2 (en) 2004-11-11
KR20010112346A (en) 2001-12-20
CA2366862C (en) 2008-05-20
KR100594666B1 (en) 2006-07-03
EP1161230A1 (en) 2001-12-12
AU3809600A (en) 2000-10-09
WO2000056290A1 (en) 2000-09-28
TR200102732T2 (en) 2002-04-22
EP1161230B1 (en) 2003-10-29
ES2208294T3 (en) 2004-06-16

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EEER Examination request
MKEX Expiry

Effective date: 20200309