CA2353802C - Nouvel antigene protecteur de streptococci du groupe a - Google Patents
Nouvel antigene protecteur de streptococci du groupe a Download PDFInfo
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- CA2353802C CA2353802C CA2353802A CA2353802A CA2353802C CA 2353802 C CA2353802 C CA 2353802C CA 2353802 A CA2353802 A CA 2353802A CA 2353802 A CA2353802 A CA 2353802A CA 2353802 C CA2353802 C CA 2353802C
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Communicable Diseases (AREA)
- General Chemical & Material Sciences (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Genetics & Genomics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
La présente invention concerne la découverte d'un nouvel antigène protecteur de Streptococcus (désigné sous le nom de Spa) qui a été identifié et isolé des Streptococci. Le Spa est un antigène de surface distinct de la protéine M qui évoque des anticorps opsoniques qui servent de protection contre de multiples sérotypes de streptococci. L'invention concerne également des polypeptides, des protéines, des peptides Spa isolés, et des anticorps contre ces derniers, ainsi que des acides nucléiques codant les antigènes peptides et polypeptides Spa. L'invention concerne en outre des méthodes d'identification et d'isolement d'un polypeptide Spa, des compositions thérapeutiques comprenant des antigènes ou des anticorps Spa et des méthodes d'utilisation de ces derniers visant à protéger un animal contre une infection de Streptococcus.
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11379498P | 1998-12-22 | 1998-12-22 | |
| US60/113,794 | 1998-12-22 | ||
| US11473098P | 1998-12-31 | 1998-12-31 | |
| US60/114,730 | 1998-12-31 | ||
| PCT/US1999/030807 WO2000037648A1 (fr) | 1998-12-22 | 1999-12-22 | Antigene protecteur de streptococci de groupe a (spa) |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2353802A1 CA2353802A1 (fr) | 2000-06-29 |
| CA2353802C true CA2353802C (fr) | 2013-10-01 |
Family
ID=26811487
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2353802A Expired - Fee Related CA2353802C (fr) | 1998-12-22 | 1999-12-22 | Nouvel antigene protecteur de streptococci du groupe a |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP1141311A1 (fr) |
| JP (1) | JP2002533084A (fr) |
| AU (1) | AU762100B2 (fr) |
| CA (1) | CA2353802C (fr) |
| WO (1) | WO2000037648A1 (fr) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6716433B1 (en) | 1997-09-12 | 2004-04-06 | University Of Tennessee Research Foundation | Group a streptococcal vaccines |
| CA2464527A1 (fr) | 2001-10-26 | 2003-08-14 | Id Biomedical Corporation Of Washington | Compositions de vaccins multivalents a base de streptocoques et procedes d'utilisation |
| US7255867B2 (en) | 2002-11-15 | 2007-08-14 | Id Biomedical Corporation Of Quebec | Vaccine |
| JP2006523142A (ja) | 2003-04-10 | 2006-10-12 | プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ | 流体種の形成および制御 |
| WO2005021151A1 (fr) | 2003-08-27 | 2005-03-10 | President And Fellows Of Harvard College | Controle electronique d'especes fluidiques |
| EP2292644A3 (fr) * | 2006-07-07 | 2011-05-25 | Intercell AG | Petits antigènes pyogènes streptococcus et leur utilisation |
| ES2648231T3 (es) | 2008-11-05 | 2017-12-29 | Wyeth Llc | Composición inmunogénica de múltiples componentes para la prevención de la enfermedad por estreptococos beta hemolíticos (EBH) |
| CA2838981C (fr) * | 2011-06-17 | 2020-09-08 | University Of Tennessee Research Foundation | Vaccin multivalent contre un streptocoque du groupe a |
| WO2014124446A1 (fr) | 2013-02-11 | 2014-08-14 | University Of Tennessee Research Foundation | Protéines apparentées à m de streptocoque de groupe a et leurs procédés d'utilisation |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1994006421A1 (fr) * | 1992-09-16 | 1994-03-31 | The University Of Tennessee Research Corporation | Vaccin a proteine m multivalente recombinee |
| AU5128593A (en) * | 1992-09-16 | 1994-04-12 | University Of Tennessee Research Corporation, The | Antigen of hybrid m protein and carrier for group a streptococcal vaccine |
| IES960488A2 (en) * | 1996-07-03 | 1997-11-19 | Trinity College Dublin | Subunit Vaccine for Streptococcus Equi |
-
1999
- 1999-12-22 JP JP2000589702A patent/JP2002533084A/ja active Pending
- 1999-12-22 EP EP99967585A patent/EP1141311A1/fr not_active Withdrawn
- 1999-12-22 AU AU23846/00A patent/AU762100B2/en not_active Ceased
- 1999-12-22 CA CA2353802A patent/CA2353802C/fr not_active Expired - Fee Related
- 1999-12-22 WO PCT/US1999/030807 patent/WO2000037648A1/fr active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| EP1141311A1 (fr) | 2001-10-10 |
| AU2384600A (en) | 2000-07-12 |
| AU762100B2 (en) | 2003-06-19 |
| JP2002533084A (ja) | 2002-10-08 |
| CA2353802A1 (fr) | 2000-06-29 |
| WO2000037648A1 (fr) | 2000-06-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| MKLA | Lapsed |
Effective date: 20181224 |