CA2353606A1 - Endoprothese comportant en surface un principe actif sous forme de cristaux - Google Patents
Endoprothese comportant en surface un principe actif sous forme de cristaux Download PDFInfo
- Publication number
- CA2353606A1 CA2353606A1 CA002353606A CA2353606A CA2353606A1 CA 2353606 A1 CA2353606 A1 CA 2353606A1 CA 002353606 A CA002353606 A CA 002353606A CA 2353606 A CA2353606 A CA 2353606A CA 2353606 A1 CA2353606 A1 CA 2353606A1
- Authority
- CA
- Canada
- Prior art keywords
- medical device
- therapeutic agent
- polymer
- coating
- crystals
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/16—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6957—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a device or a kit, e.g. stents or microdevices
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
- A61L29/08—Materials for coatings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
- A61L29/14—Materials characterised by their function or physical properties, e.g. lubricating compositions
- A61L29/16—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/08—Materials for coatings
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L75/00—Compositions of polyureas or polyurethanes; Compositions of derivatives of such polymers
- C08L75/04—Polyurethanes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/416—Anti-neoplastic or anti-proliferative or anti-restenosis or anti-angiogenic agents, e.g. paclitaxel, sirolimus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
- A61L2300/602—Type of release, e.g. controlled, sustained, slow
- A61L2300/604—Biodegradation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
- A61L2300/606—Coatings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
- A61L2300/63—Crystals
Abstract
La présente invention concerne un dispositif médical destiné à être inséré dans un corps de mammifère, le dispositif médical contenant sur sa surface un agent thérapeutique sous forme cristalline. L'invention concerne aussi une méthode d'administration d'un agent thérapeutique à un emplacement cible situé dans le corps d'un mammifère. Cette méthode consiste à placer des cristaux de l'agent thérapeutique sur un dispositif médical et à amener ce dispositif à l'emplacement cible.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US20425598A | 1998-12-03 | 1998-12-03 | |
US09/204,255 | 1998-12-03 | ||
PCT/US1999/027279 WO2000032238A1 (fr) | 1998-12-03 | 1999-11-17 | Endoprothese comportant en surface un principe actif sous forme de cristaux |
Publications (1)
Publication Number | Publication Date |
---|---|
CA2353606A1 true CA2353606A1 (fr) | 2000-06-08 |
Family
ID=22757217
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002353606A Abandoned CA2353606A1 (fr) | 1998-12-03 | 1999-11-17 | Endoprothese comportant en surface un principe actif sous forme de cristaux |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP1135165A1 (fr) |
AU (1) | AU1821200A (fr) |
CA (1) | CA2353606A1 (fr) |
WO (1) | WO2000032238A1 (fr) |
Families Citing this family (68)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20070032853A1 (en) | 2002-03-27 | 2007-02-08 | Hossainy Syed F | 40-O-(2-hydroxy)ethyl-rapamycin coated stent |
WO2001080919A2 (fr) | 2000-04-11 | 2001-11-01 | Polyzenix Gmbh | Enveloppes et films en poly-tri-fluoro-ethoxypolyphosphazene |
AU2003267309A1 (en) | 2000-11-16 | 2004-04-08 | Microspherix Llc | Flexible and/or elastic brachytherapy seed or strand |
WO2002068000A2 (fr) * | 2000-11-16 | 2002-09-06 | Microspherix Llc | Grain de brachytherapie imageable polymere |
US6746661B2 (en) | 2000-11-16 | 2004-06-08 | Microspherix Llc | Brachytherapy seed |
US9080146B2 (en) | 2001-01-11 | 2015-07-14 | Celonova Biosciences, Inc. | Substrates containing polyphosphazene as matrices and substrates containing polyphosphazene with a micro-structured surface |
DE10115740A1 (de) | 2001-03-26 | 2002-10-02 | Ulrich Speck | Zubereitung für die Restenoseprophylaxe |
ES2220247T3 (es) * | 2001-05-07 | 2007-11-16 | Cornell Research Foundation, Inc. | Copolimeros biodegradables enlazados a un segmento con una pluralidad de grupos funcionales. |
EP1432380B1 (fr) | 2001-08-17 | 2006-09-27 | Polyzenix GmbH | Dispositif a base de nitinol comportant un revetement polyphosphate |
CA2484383C (fr) | 2002-07-12 | 2016-05-31 | Cook Incorporated | Appareil medical recouvert d'un agent bioactif |
DE10244847A1 (de) | 2002-09-20 | 2004-04-01 | Ulrich Prof. Dr. Speck | Medizinische Vorrichtung zur Arzneimittelabgabe |
US20050118344A1 (en) | 2003-12-01 | 2005-06-02 | Pacetti Stephen D. | Temperature controlled crimping |
US8551512B2 (en) | 2004-03-22 | 2013-10-08 | Advanced Cardiovascular Systems, Inc. | Polyethylene glycol/poly(butylene terephthalate) copolymer coated devices including EVEROLIMUS |
US20210299056A9 (en) | 2004-10-25 | 2021-09-30 | Varian Medical Systems, Inc. | Color-Coded Polymeric Particles of Predetermined Size for Therapeutic and/or Diagnostic Applications and Related Methods |
US9114162B2 (en) | 2004-10-25 | 2015-08-25 | Celonova Biosciences, Inc. | Loadable polymeric particles for enhanced imaging in clinical applications and methods of preparing and using the same |
US9107850B2 (en) | 2004-10-25 | 2015-08-18 | Celonova Biosciences, Inc. | Color-coded and sized loadable polymeric particles for therapeutic and/or diagnostic applications and methods of preparing and using the same |
WO2007011707A2 (fr) | 2005-07-15 | 2007-01-25 | Micell Technologies, Inc. | Enrobages polymeres renfermant de la poudre de medicament a morphologie commandee |
WO2007011708A2 (fr) | 2005-07-15 | 2007-01-25 | Micell Technologies, Inc. | Stent a revetement polymere renfermant de la rapamycine amorphe |
AU2011256902B2 (en) * | 2005-07-15 | 2015-03-12 | Micell Technologies, Inc. | Polymer coatings containing drug powder of controlled morphology |
US7842312B2 (en) | 2005-12-29 | 2010-11-30 | Cordis Corporation | Polymeric compositions comprising therapeutic agents in crystalline phases, and methods of forming the same |
US7919108B2 (en) * | 2006-03-10 | 2011-04-05 | Cook Incorporated | Taxane coatings for implantable medical devices |
US7875284B2 (en) | 2006-03-10 | 2011-01-25 | Cook Incorporated | Methods of manufacturing and modifying taxane coatings for implantable medical devices |
ES2540059T3 (es) | 2006-04-26 | 2015-07-08 | Micell Technologies, Inc. | Recubrimientos que contienen múltiples fármacos |
WO2008033199A1 (fr) * | 2006-09-12 | 2008-03-20 | Boston Scientific Limited | Dépôt de masque liquide pour le revêtement sélectif d'une endoprothèse vasculaire |
EP2111184B1 (fr) | 2007-01-08 | 2018-07-25 | Micell Technologies, Inc. | Stents comportant des couches biodégradables |
US11426494B2 (en) | 2007-01-08 | 2022-08-30 | MT Acquisition Holdings LLC | Stents having biodegradable layers |
DE102007003184A1 (de) * | 2007-01-22 | 2008-07-24 | Orlowski, Michael, Dr. | Verfahren zur Beladung von strukturierten Oberflächen |
US9433516B2 (en) | 2007-04-17 | 2016-09-06 | Micell Technologies, Inc. | Stents having controlled elution |
US8802184B2 (en) | 2007-05-30 | 2014-08-12 | Abbott Cardiovascular Systems Inc. | Medical devices containing biobeneficial particles |
US9192697B2 (en) | 2007-07-03 | 2015-11-24 | Hemoteq Ag | Balloon catheter for treating stenosis of body passages and for preventing threatening restenosis |
US8679519B2 (en) | 2007-10-23 | 2014-03-25 | Abbott Cardiovascular Systems Inc. | Coating designs for the tailored release of dual drugs from polymeric coatings |
AU2009251504B2 (en) | 2008-04-17 | 2013-09-05 | Micell Technologies, Inc. | Stents having bioabsorbable layers |
US9533078B2 (en) | 2008-06-25 | 2017-01-03 | Boston Scientific Scimed, Inc. | Medical devices containing therapeutic agents |
AU2009270849B2 (en) | 2008-07-17 | 2013-11-21 | Micell Technologies, Inc. | Drug delivery medical device |
WO2011009096A1 (fr) | 2009-07-16 | 2011-01-20 | Micell Technologies, Inc. | Dispositif médical distributeur de médicament |
US8500687B2 (en) | 2008-09-25 | 2013-08-06 | Abbott Cardiovascular Systems Inc. | Stent delivery system having a fibrous matrix covering with improved stent retention |
IT1394522B1 (it) * | 2009-01-09 | 2012-07-05 | Invatec Technology Ct Gmbh | Dispositivo medicale con rilascio di farmaco |
US20120231037A1 (en) | 2009-02-02 | 2012-09-13 | Yissum Research Development Companyof the Hebrew U | Crystalline drug-containing coatings |
JP2012522589A (ja) | 2009-04-01 | 2012-09-27 | ミシェル テクノロジーズ,インコーポレイテッド | 被覆ステント |
WO2011005421A2 (fr) * | 2009-07-10 | 2011-01-13 | Boston Scientific Scimed, Inc. | Utilisation de nanocristaux pour un ballonnet de distribution de médicament |
JP5933434B2 (ja) | 2009-07-17 | 2016-06-08 | ボストン サイエンティフィック サイムド,インコーポレイテッドBoston Scientific Scimed,Inc. | 薬剤送達バルーンの製造方法 |
EP2501431B1 (fr) | 2009-11-19 | 2020-01-08 | Wellinq Medical B.V. | Cathéter médical à ballonet extensible, libérant une composition et de profil étroit |
US11369498B2 (en) | 2010-02-02 | 2022-06-28 | MT Acquisition Holdings LLC | Stent and stent delivery system with improved deliverability |
US10232092B2 (en) | 2010-04-22 | 2019-03-19 | Micell Technologies, Inc. | Stents and other devices having extracellular matrix coating |
EP2593039B1 (fr) | 2010-07-16 | 2022-11-30 | Micell Technologies, Inc. | Dispositif médical d'administration de médicament |
US8889211B2 (en) | 2010-09-02 | 2014-11-18 | Boston Scientific Scimed, Inc. | Coating process for drug delivery balloons using heat-induced rewrap memory |
CA2841360A1 (fr) | 2011-07-15 | 2013-01-24 | Micell Technologies, Inc. | Dispositif medical d'administration de medicament |
US9056152B2 (en) | 2011-08-25 | 2015-06-16 | Boston Scientific Scimed, Inc. | Medical device with crystalline drug coating |
US10188772B2 (en) | 2011-10-18 | 2019-01-29 | Micell Technologies, Inc. | Drug delivery medical device |
US10850076B2 (en) | 2012-10-26 | 2020-12-01 | Urotronic, Inc. | Balloon catheters for body lumens |
US11938287B2 (en) | 2012-10-26 | 2024-03-26 | Urotronic, Inc. | Drug-coated balloon catheters for body lumens |
US11504450B2 (en) | 2012-10-26 | 2022-11-22 | Urotronic, Inc. | Drug-coated balloon catheters for body lumens |
JP2015536709A (ja) | 2012-10-26 | 2015-12-24 | ウロトロニック・インコーポレイテッドUrotronic, Inc. | 非血管狭窄のための薬物被覆バルーンカテーテル |
US10898700B2 (en) | 2012-10-26 | 2021-01-26 | Urotronic, Inc. | Balloon catheters for body lumens |
US10806830B2 (en) | 2012-10-26 | 2020-10-20 | Urotronic, Inc. | Drug-coated balloon catheters for body lumens |
US10881839B2 (en) | 2012-10-26 | 2021-01-05 | Urotronic, Inc. | Drug-coated balloon catheters for body lumens |
AU2014248508B2 (en) | 2013-03-12 | 2018-11-08 | Micell Technologies, Inc. | Bioabsorbable biomedical implants |
AU2014265460B2 (en) | 2013-05-15 | 2018-10-18 | Micell Technologies, Inc. | Bioabsorbable biomedical implants |
DE102013014821A1 (de) * | 2013-09-10 | 2015-03-12 | Alexander Rübben | Gefäßendoprothesenbeschichtung |
DE102013110294B4 (de) | 2013-09-18 | 2016-07-07 | Innora Gmbh | Limus-Depot-Formulierung auf Ballonkathetern |
US20150196489A1 (en) * | 2013-12-18 | 2015-07-16 | Massachusetts Institute Of Technology | Polymer matrices for controlling crystallization |
WO2015181826A1 (fr) | 2014-05-27 | 2015-12-03 | Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. | Revêtement cristallin et libération d'agents bioactifs |
US11241520B2 (en) | 2014-08-07 | 2022-02-08 | Cook Medical Technologies Llc | Compositions and devices incorporating water-insoluble therapeutic agents and methods of the use thereof |
US9655998B2 (en) | 2014-08-07 | 2017-05-23 | Cook Medical Technologies Llc | Encapsulated drug compositions and methods of use thereof |
US9180226B1 (en) | 2014-08-07 | 2015-11-10 | Cook Medical Technologies Llc | Compositions and devices incorporating water-insoluble therapeutic agents and methods of the use thereof |
US11904072B2 (en) | 2015-04-24 | 2024-02-20 | Urotronic, Inc. | Drug coated balloon catheters for nonvascular strictures |
US10888640B2 (en) | 2015-04-24 | 2021-01-12 | Urotronic, Inc. | Drug coated balloon catheters for nonvascular strictures |
EP3927410A1 (fr) | 2019-02-22 | 2021-12-29 | Urotronic, Inc. | Cathéters à ballonnet revêtus de médicament pour lumières corporelles |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6515009B1 (en) * | 1991-09-27 | 2003-02-04 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
ES2290074T3 (es) * | 1993-07-19 | 2008-02-16 | Angiotech Pharmaceuticals, Inc. | Composiciones anti-angiogenicas que contienen taxol y un vehiculo no biodegradable y su uso. |
ES2226120T3 (es) * | 1997-03-31 | 2005-03-16 | Boston Scientific Limited | Inhibidor terapeutico de celulas del musculo liso vascular. |
-
1999
- 1999-11-17 EP EP99961692A patent/EP1135165A1/fr not_active Withdrawn
- 1999-11-17 CA CA002353606A patent/CA2353606A1/fr not_active Abandoned
- 1999-11-17 WO PCT/US1999/027279 patent/WO2000032238A1/fr not_active Application Discontinuation
- 1999-11-17 AU AU18212/00A patent/AU1821200A/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
AU1821200A (en) | 2000-06-19 |
EP1135165A1 (fr) | 2001-09-26 |
WO2000032238A9 (fr) | 2000-12-07 |
WO2000032238A1 (fr) | 2000-06-08 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FZDE | Discontinued | ||
FZDE | Discontinued |
Effective date: 20031117 |