CA2352599A1 - Mediateurs nf-at de l'hypertrophie cardiaque, procedes et reactifs correspondants - Google Patents

Mediateurs nf-at de l'hypertrophie cardiaque, procedes et reactifs correspondants Download PDF

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Publication number
CA2352599A1
CA2352599A1 CA002352599A CA2352599A CA2352599A1 CA 2352599 A1 CA2352599 A1 CA 2352599A1 CA 002352599 A CA002352599 A CA 002352599A CA 2352599 A CA2352599 A CA 2352599A CA 2352599 A1 CA2352599 A1 CA 2352599A1
Authority
CA
Canada
Prior art keywords
polypeptide
antagonist
cell
cells
protein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002352599A
Other languages
English (en)
Inventor
Gerald R. Crabtree
Jeffrey P. Northrop
Steffan N. Ho
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Leland Stanford Junior University
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2352599A1 publication Critical patent/CA2352599A1/fr
Abandoned legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8103—Exopeptidase (E.C. 3.4.11-19) inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

Cette invention se rapporte à un procédé servant à traiter l'hypertrophie cardiaque ou à prévenir toute croissance de tissus cardiaques et vasculaires grâce à l'utilisation d'antagonistes NF-AT.
CA002352599A 1998-11-24 1999-11-23 Mediateurs nf-at de l'hypertrophie cardiaque, procedes et reactifs correspondants Abandoned CA2352599A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US19897798A 1998-11-24 1998-11-24
US09/198,977 1998-11-24
PCT/US1999/027862 WO2000030671A2 (fr) 1998-11-24 1999-11-23 Mediateurs nf-at de l'hypertrophie cardiaque, procedes et reactifs correspondants

Publications (1)

Publication Number Publication Date
CA2352599A1 true CA2352599A1 (fr) 2000-06-02

Family

ID=22735695

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002352599A Abandoned CA2352599A1 (fr) 1998-11-24 1999-11-23 Mediateurs nf-at de l'hypertrophie cardiaque, procedes et reactifs correspondants

Country Status (5)

Country Link
EP (1) EP1131086A2 (fr)
JP (1) JP2002530349A (fr)
CA (1) CA2352599A1 (fr)
IL (1) IL143297A0 (fr)
WO (1) WO2000030671A2 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6687428B2 (en) 2000-09-21 2004-02-03 Tera Op (Usa) Inc. Optical switch
US20130183686A1 (en) * 2008-11-11 2013-07-18 Donna Davidovich Method of evaluating immunosuppression

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6197925B1 (en) * 1991-08-22 2001-03-06 Sara Lee Corporation NF-AT polypeptides and polynucleotides
EP0656067A4 (fr) * 1991-08-22 1995-10-25 Univ Leland Stanford Junior Procedes de depistage d'agents immunosuppressifs.
US5656452A (en) * 1993-01-15 1997-08-12 President And Fellows Of Harvard College NF-ATp, ' a T lymphocyte DNA-binding protein
AU7562594A (en) * 1993-08-18 1995-03-14 Board Of Trustees Of The Leland Stanford Junior University Sequence-specific glycoconjugate transcriptional antagonists
US5612455A (en) * 1994-07-05 1997-03-18 Tularik, Inc. Nuclear factors and binding assay
CA2306448A1 (fr) * 1997-10-16 1999-04-22 Board Of Regents, The University Of Texas System Modeles et traitement de l'hypertrophie cardiaque en liaison avec la fonction nf-at3
WO1999040930A1 (fr) * 1998-02-12 1999-08-19 Center For Blood Research, Inc. Inhibiteurs specifiques d'activation des proteines nfat par la calcineurine, et utilisation dans le traitement des maladies liees a l'immunisation

Also Published As

Publication number Publication date
WO2000030671A9 (fr) 2001-05-17
WO2000030671A3 (fr) 2000-11-09
WO2000030671A2 (fr) 2000-06-02
IL143297A0 (en) 2002-04-21
EP1131086A2 (fr) 2001-09-12
JP2002530349A (ja) 2002-09-17

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Legal Events

Date Code Title Description
FZDE Discontinued