CA2349451A1 - Composes diazaanthracene substitues d'utilite pharmaceutique - Google Patents

Composes diazaanthracene substitues d'utilite pharmaceutique Download PDF

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Publication number
CA2349451A1
CA2349451A1 CA002349451A CA2349451A CA2349451A1 CA 2349451 A1 CA2349451 A1 CA 2349451A1 CA 002349451 A CA002349451 A CA 002349451A CA 2349451 A CA2349451 A CA 2349451A CA 2349451 A1 CA2349451 A1 CA 2349451A1
Authority
CA
Canada
Prior art keywords
compound
diazaanthracene
daa
dimethyl
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002349451A
Other languages
English (en)
Inventor
Michael John Zaworotko
Subramanian Sethuraman Iyer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Diazans Ltd
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2349451A1 publication Critical patent/CA2349451A1/fr
Abandoned legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

L'invention concerne des diazaanthracènes des formules (I) et (II). La ligne en pointillé dans le noyau central indique que le noyau central est aromatiquement insaturé et, en l'occurrence, soit R?3¿, soit H est absent de la position 10, soit R?4¿, soit H est absent de la position 5. Autre possibilité, le noyau central est saturé et, par conséquent, R?3¿ et H, et R?4¿ et H sont présents. Les 5,10-diones, N-oxydes, N-halogénures, N-amine, sels, dimères, composés d'addition Diels-Alder, composés d'addition carbène et complexes correspondants avec composés métalliques de transition présentent de précieuses propriétés antibactériennes, anticancéreuses et antifongiques. Les composés des formules (I) et (II), dans lesquelles R?1¿ et R?2¿ sont tous deux des groupes méthyle, peuvent être obtenus en soumettant 3,5-lutidine à l'action d'un puissant agent de réduction, par exemple du sodium fondu.
CA002349451A 1999-09-03 1999-09-03 Composes diazaanthracene substitues d'utilite pharmaceutique Abandoned CA2349451A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/CA1999/000812 WO2001017997A1 (fr) 1999-09-03 1999-09-03 Composes diazaanthracene substitues d'utilite pharmaceutique

Publications (1)

Publication Number Publication Date
CA2349451A1 true CA2349451A1 (fr) 2001-03-15

Family

ID=4173383

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002349451A Abandoned CA2349451A1 (fr) 1999-09-03 1999-09-03 Composes diazaanthracene substitues d'utilite pharmaceutique

Country Status (3)

Country Link
AU (1) AU5500699A (fr)
CA (1) CA2349451A1 (fr)
WO (1) WO2001017997A1 (fr)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4335130A (en) * 1981-05-12 1982-06-15 Morton-Norwich Products, Inc. Antifungal composition

Also Published As

Publication number Publication date
WO2001017997A1 (fr) 2001-03-15
AU5500699A (en) 2001-04-10

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