CA2345710A1 - Preparation de composes haloaromatiques radiomarques au moyen d'intermediaires a liaison polymere - Google Patents

Preparation de composes haloaromatiques radiomarques au moyen d'intermediaires a liaison polymere Download PDF

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Publication number
CA2345710A1
CA2345710A1 CA002345710A CA2345710A CA2345710A1 CA 2345710 A1 CA2345710 A1 CA 2345710A1 CA 002345710 A CA002345710 A CA 002345710A CA 2345710 A CA2345710 A CA 2345710A CA 2345710 A1 CA2345710 A1 CA 2345710A1
Authority
CA
Canada
Prior art keywords
preparation
radiolabelled
haloaromatics
via polymer
bound intermediates
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002345710A
Other languages
English (en)
Other versions
CA2345710C (fr
Inventor
Duncan H. Hunter
Xizhen Zhu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Western Ontario
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2345710A1 publication Critical patent/CA2345710A1/fr
Application granted granted Critical
Publication of CA2345710C publication Critical patent/CA2345710C/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00—Chemical modification by after-treatment
    • C08F8/30—Introducing nitrogen atoms or nitrogen-containing groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
    • C07B59/001—Acyclic or carbocyclic compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C277/00—Preparation of guanidine or its derivatives, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C277/08—Preparation of guanidine or its derivatives, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups of substituted guanidines
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00—Chemical modification by after-treatment
    • C08F8/42—Introducing metal atoms or metal-containing groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
CA002345710A 1997-10-02 1998-10-02 Preparation de composes haloaromatiques radiomarques au moyen d'intermediaires a liaison polymere Expired - Lifetime CA2345710C (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US6088697P 1997-10-02 1997-10-02
US60/060,886 1997-10-02
PCT/CA1998/000933 WO1999018053A1 (fr) 1997-10-02 1998-10-02 Preparation de composes haloaromatiques radiomarques au moyen d'intermediaires a liaison polymere

Publications (2)

Publication Number Publication Date
CA2345710A1 true CA2345710A1 (fr) 1999-04-15
CA2345710C CA2345710C (fr) 2008-12-30

Family

ID=22032357

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002345710A Expired - Lifetime CA2345710C (fr) 1997-10-02 1998-10-02 Preparation de composes haloaromatiques radiomarques au moyen d'intermediaires a liaison polymere

Country Status (2)

Country Link
CA (1) CA2345710C (fr)
WO (1) WO1999018053A1 (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7273601B2 (en) 2000-07-18 2007-09-25 The University Of Western Ontario Preparation of radiolabelled haloaromatics via polymer-bound intermediates
AU2002258100B2 (en) 2001-03-02 2007-03-01 University Of Western Ontario Polymer precursors of radiolabeled compounds, and methods of making and using the same
AU2003301432B2 (en) * 2002-10-18 2008-11-06 Mcmaster University Methods for purifying radiolabelled compounds
GB0229686D0 (en) * 2002-12-20 2003-01-29 Amersham Plc Solid-phase fluorination of benzothiazoles
JP5265869B2 (ja) * 2003-05-02 2013-08-14 ザ ユニバーシティー オブ ウェスタン オンタリオ 放射性医薬化合物の合成に有用な補欠分子族
EP1571150A1 (fr) * 2004-03-02 2005-09-07 Aventis Pharma Deutschland GmbH Procédé pour la prparation des inhibiteurs de tryptase
GB0410448D0 (en) * 2004-05-11 2004-06-16 Hammersmith Imanet Ltd Purification methods
EP2474526A3 (fr) * 2006-12-26 2012-07-25 Lantheus Medical Imaging, Inc. Ligands pour l'imagerie de l'innervation cardiaque
BR122020018194B1 (pt) 2010-05-11 2021-07-27 Lantheus Medical Imaging, Inc. Composições e métodos de síntese de agentes de imagiologia
EP2891657A1 (fr) 2014-01-07 2015-07-08 Centre National de la Recherche Scientifique (CNRS) Réactifs organostannane supportés par un liquide ionique pour la fabrication de composés radiopharmaceutiques
EP3131877B1 (fr) 2014-04-17 2023-07-19 Immunomet Therapeutics Inc. Composés à base de biguanide

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5565185A (en) * 1994-07-20 1996-10-15 Merck Frosst Canada, Inc. Process for the preparation of radiolabeled meta-halobenzylguanidine

Also Published As

Publication number Publication date
CA2345710C (fr) 2008-12-30
WO1999018053A1 (fr) 1999-04-15

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EEER Examination request
MKEX Expiry

Effective date: 20181002