CA2344050A1 - Compositions antibiotiques pour le traitement des yeux, des oreilles et du nez - Google Patents

Compositions antibiotiques pour le traitement des yeux, des oreilles et du nez Download PDF

Info

Publication number
CA2344050A1
CA2344050A1 CA002344050A CA2344050A CA2344050A1 CA 2344050 A1 CA2344050 A1 CA 2344050A1 CA 002344050 A CA002344050 A CA 002344050A CA 2344050 A CA2344050 A CA 2344050A CA 2344050 A1 CA2344050 A1 CA 2344050A1
Authority
CA
Canada
Prior art keywords
group
otic
ophthalmic
alkyl
nasal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002344050A
Other languages
English (en)
Inventor
John M. Yanni
Gerald Cagle
Robert L. Abshire
David W. Stroman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alcon Vision LLC
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2344050A1 publication Critical patent/CA2344050A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

L'invention concerne des compositions antibiotiques pour le traitement des yeux, des oreilles et du nez, renfermant une nouvelle catégorie d'antibiotiques (par exemple, moxifloxacine). De préférence, les compositions contiennent aussi un ou plusieurs anti-inflammatoires. On peut utiliser ces compositions pour traiter les affections des yeux, des oreilles et du nez, par application topique sur les tissus affectés.
CA002344050A 1998-09-30 1999-09-29 Compositions antibiotiques pour le traitement des yeux, des oreilles et du nez Abandoned CA2344050A1 (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US10251098P 1998-09-30 1998-09-30
US10251198P 1998-09-30 1998-09-30
US60/102,510 1998-09-30
US60/102,511 1998-09-30
PCT/US1999/022625 WO2000018404A1 (fr) 1998-09-30 1999-09-29 Compositions antibiotiques pour le traitement des yeux, des oreilles et du nez

Publications (1)

Publication Number Publication Date
CA2344050A1 true CA2344050A1 (fr) 2000-04-06

Family

ID=26799456

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002344050A Abandoned CA2344050A1 (fr) 1998-09-30 1999-09-29 Compositions antibiotiques pour le traitement des yeux, des oreilles et du nez

Country Status (7)

Country Link
EP (1) EP1117406A1 (fr)
JP (1) JP2002525326A (fr)
AU (1) AU6275999A (fr)
BR (1) BR9914158A (fr)
CA (1) CA2344050A1 (fr)
HK (1) HK1038692A1 (fr)
WO (1) WO2000018404A1 (fr)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6509327B1 (en) 1998-09-30 2003-01-21 Alcon Manufacturing, Ltd. Compositions and methods for treating otic, ophthalmic and nasal infections
US6395746B1 (en) 1998-09-30 2002-05-28 Alcon Manufacturing, Ltd. Methods of treating ophthalmic, otic and nasal infections and attendant inflammation
US6716830B2 (en) 1998-09-30 2004-04-06 Alcon, Inc. Ophthalmic antibiotic compositions containing moxifloxacin
PL201130B1 (pl) 1999-09-24 2009-03-31 Alcon Inc Kompozycje zawiesinowe zawierające ciprofloksacynę i deksametazon do podawania miejscowego do oczu, uszu lub nosa
AU2005202737B2 (en) * 1999-12-22 2009-01-22 Bayer Innovation Gmbh Use of chemotherapeutic agents
DE19962470A1 (de) 1999-12-22 2001-07-12 Schulz Hans Herrmann Verwendung von Chemotherapeutika
DE19962353A1 (de) 1999-12-23 2001-07-05 Henkel Ecolab Gmbh & Co Ohg Hepatitis A Viruzid
US6608078B2 (en) 2000-05-08 2003-08-19 Wockhardt Limited Antibacterial chiral 8-(substituted piperidino)-benzo [i,j] quinolizines, processes, compositions and methods of treatment
CA2412575C (fr) 2000-07-26 2009-12-29 Onkar N. Singh Procede ameliore de fabrication de compositions contenant de la ciprofloxacine et de l'hydrocortisone
US7098219B2 (en) 2000-08-01 2006-08-29 Wockhart Limited Inhibitors of cellular efflux pumps of microbes
US6964966B2 (en) * 2001-04-25 2005-11-15 Wockhardt Limited Generation triple-targeting, chiral, broad-spectrum antimicrobial 7-substituted piperidino-quinolone carboxylic acid derivatives, their preparation, compositions and use as medicaments
US6878713B2 (en) 2001-04-25 2005-04-12 Wockhardt Limited Generation triple-targeting, chiral, broad-spectrum antimicrobial 7-substituted piperidino-quinolone carboxylic acid derivatives, their preparation, compositions and use as medicaments
EP1429780B1 (fr) 2001-09-21 2005-12-21 Alcon, Inc. Procede de traitement de l'infection de l'oreille moyenne
AU2002361493A1 (en) * 2001-12-13 2003-06-23 Wockhardt Limited New generation triple-targeting, chiral, broad-spectrum antimicrobial 7-substituted piperidino-quinolone carboxylic acid derivatives, their preparation, compositions and use as medicaments
US6664267B1 (en) 2002-05-28 2003-12-16 Wockhardt Limited Crystalline fluoroquinolone arginine salt form
JP2006510657A (ja) * 2002-12-06 2006-03-30 アライバ ファーマシューティカルズ，インコーポレイティド 中耳炎の処置のための方法および組成物
EP1660495B1 (fr) 2003-09-04 2007-07-11 Wockhardt Limited Arginine tetrahydrate d'acide benzoquinolizine-2-carboxylique
US20090042936A1 (en) * 2007-08-10 2009-02-12 Ward Keith W Compositions and Methods for Treating or Controlling Anterior-Segment Inflammation
WO2012177251A1 (fr) * 2011-06-22 2012-12-27 Adeda Therapeutics Company Limited Compositions pharmaceutiques comprenant de l'iode et un stéroïde, et utilisations de celles-ci dans le traitement d'affections sinusiennes

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4551456A (en) * 1983-11-14 1985-11-05 Merck & Co., Inc. Ophthalmic use of norfloxacin and related antibiotics
JP2549285B2 (ja) * 1987-02-02 1996-10-30 第一製薬株式会社 鼻用噴霧剤
US5591744A (en) * 1987-04-16 1997-01-07 Otsuka Pharmaceutical Company, Limited Benzoheterocyclic compounds
AU4201189A (en) * 1988-08-26 1990-03-23 Alcon Laboratories, Inc. Combination of quinolone antibiotics and steroids for topical ophthalmic use
ES2173287T3 (es) * 1995-06-06 2002-10-16 Bayer Ag Composiciones oticas antibacterianas no irritantes, no sensibilizantes y no ototoxicas.
JPH10130148A (ja) * 1996-09-04 1998-05-19 Senju Pharmaceut Co Ltd ネブライザー用組成物

Also Published As

Publication number Publication date
EP1117406A1 (fr) 2001-07-25
JP2002525326A (ja) 2002-08-13
HK1038692A1 (zh) 2002-03-28
WO2000018404A1 (fr) 2000-04-06
AU6275999A (en) 2000-04-17
BR9914158A (pt) 2001-06-26

Similar Documents

Publication Publication Date Title
US6716830B2 (en) Ophthalmic antibiotic compositions containing moxifloxacin
CA2342211C (fr) Compositions antibiotiques pour le traitement des yeux, des oreilles et du nez
US6395746B1 (en) Methods of treating ophthalmic, otic and nasal infections and attendant inflammation
CA2344050A1 (fr) Compositions antibiotiques pour le traitement des yeux, des oreilles et du nez
US20020142999A1 (en) Antibiotic compositions for treatment of the eye, ear and nose
AU2003248033B2 (en) Antibiotic Compositions for Treatment of the Eye, Ear and Nose
MXPA01003294A (en) Antibiotic compositions for treatment of the eye, ear and nose
MXPA01003295A (en) Antibiotic compositions for treatment of the eye, ear and nose
ZA200101752B (en) Methods of treating or preventing ophthalmi infections with moxifloxacin.
MXPA01003293A (en) Antibiotic compositions for treatment of the eye, ear and nose
AU2007201610A1 (en) Antibiotic compositions for treatment of the eye, ear and nose

Legal Events

Date Code Title Description
FZDE Dead