CA2341754A1 - Cellules souches portant a leur surface un recepteur fgf - Google Patents
Cellules souches portant a leur surface un recepteur fgf Download PDFInfo
- Publication number
- CA2341754A1 CA2341754A1 CA002341754A CA2341754A CA2341754A1 CA 2341754 A1 CA2341754 A1 CA 2341754A1 CA 002341754 A CA002341754 A CA 002341754A CA 2341754 A CA2341754 A CA 2341754A CA 2341754 A1 CA2341754 A1 CA 2341754A1
- Authority
- CA
- Canada
- Prior art keywords
- cells
- fgfr
- stem cells
- lin
- composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0662—Stem cells
- C12N5/0663—Bone marrow mesenchymal stem cells (BM-MSC)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0647—Haematopoietic stem cells; Uncommitted or multipotent progenitors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0662—Stem cells
- C12N5/0665—Blood-borne mesenchymal stem cells, e.g. from umbilical cord blood
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/069—Vascular Endothelial cells
- C12N5/0692—Stem cells; Progenitor cells; Precursor cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Developmental Biology & Embryology (AREA)
- Hematology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Cell Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Engineering & Computer Science (AREA)
- Rheumatology (AREA)
- Immunology (AREA)
- Surgery (AREA)
- Diabetes (AREA)
- Vascular Medicine (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Composition de cellules souches pluripotentes sensiblement purifiées présentant un récepteur du facteur de croissance des fibroblastes (FGFR) et un phénotype indiquant un état primitif telles que des cellules souches CD34?+¿, CD34?-¿lin?-¿, Thy-1?+¿, AC133?+¿ ou c-kit?+¿. L'état de cellule souche embryonnaire est également un phénotype qui indique un état primitif. Cette population peut également être définie par des sous-populations de cette dernière portant un autre marqueur qui indique des cellules endothéliales, telles que des cellules TIE-1?+¿, TEK?+¿, CD31?+¿, VE-Cadhérine?+¿ ou VEGFR?+¿ ou qui indique des cellules de stroma, telles que des cellules STRO-1?+¿.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US9848098P | 1998-08-31 | 1998-08-31 | |
US60/098,480 | 1998-08-31 | ||
PCT/US1999/019730 WO2000012683A2 (fr) | 1998-08-31 | 1999-08-31 | Cellules souches portant a leur surface un recepteur fgf |
Publications (1)
Publication Number | Publication Date |
---|---|
CA2341754A1 true CA2341754A1 (fr) | 2000-03-09 |
Family
ID=22269466
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002341754A Abandoned CA2341754A1 (fr) | 1998-08-31 | 1999-08-31 | Cellules souches portant a leur surface un recepteur fgf |
Country Status (7)
Country | Link |
---|---|
EP (1) | EP1117765A2 (fr) |
JP (1) | JP2002523085A (fr) |
AU (1) | AU774581B2 (fr) |
CA (1) | CA2341754A1 (fr) |
IL (1) | IL141683A0 (fr) |
WO (1) | WO2000012683A2 (fr) |
ZA (1) | ZA200101622B (fr) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20030125615A1 (en) * | 1998-02-05 | 2003-07-03 | Yitzhack Schwartz | Homing of autologous cells to a target zone in tissue using active therapeutics or substances |
DE60037007T2 (de) * | 1999-02-12 | 2008-08-21 | Stemcells California, Inc., Palo Alto | Angereicherte zentralnervensystem-zellpopulationen |
US7217565B2 (en) | 1999-02-12 | 2007-05-15 | Stemcells California, Inc. | Enriched central nervous system stem cell and progenitor cell populations, and methods for identifying, isolating and enriching for such populations |
US7037719B1 (en) | 1999-02-12 | 2006-05-02 | Stemcells California, Inc. | Enriched central nervous system stem cell and progenitor cell populations, and methods for identifying, isolating and enriching for such populations |
US6468794B1 (en) | 1999-02-12 | 2002-10-22 | Stemcells, Inc. | Enriched central nervous system stem cell and progenitor cell populations, and methods for identifying, isolating and enriching for such populations |
US7105150B2 (en) | 1999-02-12 | 2006-09-12 | Stemcells California, Inc. | In vivo screening methods using enriched neural stem cells |
FR2808803B1 (fr) * | 2000-05-11 | 2004-12-10 | Agronomique Inst Nat Rech | Cellules es modifiees et gene specifique de cellules es |
KR100947577B1 (ko) * | 2000-06-26 | 2010-03-15 | 엔씨 메디컬 리서치 가부시키가이샤 | 신경계 세포로 분화할 수 있는 세포를 포함하는 세포분획 |
AU8617301A (en) | 2000-08-01 | 2002-02-13 | Yissum Res Dev Co | Directed differentiation of embryonic cells |
US7247477B2 (en) * | 2002-04-16 | 2007-07-24 | Technion Research & Development Foundation Ltd. | Methods for the in-vitro identification, isolation and differentiation of vasculogenic progenitor cells |
US7470538B2 (en) | 2002-12-05 | 2008-12-30 | Case Western Reserve University | Cell-based therapies for ischemia |
ITNA20040043A1 (it) * | 2004-07-28 | 2004-10-28 | Francesco Carinci | Tecnica di ingegneria tissutale ottenibile mediante isolamento di una nuova sottopopolazione di cellule staminali mbp-shed ed mbp-dpsc, isolate da polpa di denti decidui e permanenti in grado di produrre in vitro tessuto osseo umano. |
US20110076255A1 (en) | 2005-11-07 | 2011-03-31 | Pecora Andrew L | Compositions and methods for treating progressive myocardial injury due to a vascular insufficiency |
US8637005B2 (en) | 2005-11-07 | 2014-01-28 | Amorcyte, Inc. | Compositions and methods of vascular injury repair |
SI2441461T1 (sl) | 2005-11-07 | 2014-09-30 | Amorcyte, Inc. | Sestavki in postopki za reparacijo vaskularne poškodbe |
BRPI0920976A2 (pt) | 2008-12-03 | 2015-08-18 | Amorcyte Inc | Composições que melhoram a perfusão da area de infarto e metodos de restauração da lesão vascular. |
EP2559509B1 (fr) | 2011-08-16 | 2014-12-31 | Seco Tools Ab | Insert de découpe indexable à double face et outil de découpe incluant un tel insert |
CN107362357B (zh) | 2013-02-06 | 2021-04-27 | Nc医学研究公司 | 用于治疗神经变性的细胞疗法 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5690926A (en) * | 1992-10-08 | 1997-11-25 | Vanderbilt University | Pluripotential embryonic cells and methods of making same |
US5505908A (en) * | 1994-09-01 | 1996-04-09 | Halozone Technologies, Inc. | Recycling and recovery of methyl bromide fumigant |
ATE273384T1 (de) * | 1995-04-06 | 2004-08-15 | Regeneron Pharma | Tie-2 liganden, herstellungsverfahren und verwendung |
JP4018142B2 (ja) * | 1996-01-23 | 2007-12-05 | インデバス ファーマシューティカルズ,インコーポレーテッド | 造血発生を刺激するためのobese遺伝子およびその産物の使用方法 |
FR2756570B1 (fr) * | 1996-12-03 | 2002-09-27 | Commissariat Energie Atomique | Promoteur de la ve-cadherine et ses utilisations |
-
1999
- 1999-08-31 IL IL14168399A patent/IL141683A0/xx unknown
- 1999-08-31 AU AU56967/99A patent/AU774581B2/en not_active Ceased
- 1999-08-31 JP JP2000567670A patent/JP2002523085A/ja active Pending
- 1999-08-31 WO PCT/US1999/019730 patent/WO2000012683A2/fr not_active Application Discontinuation
- 1999-08-31 CA CA002341754A patent/CA2341754A1/fr not_active Abandoned
- 1999-08-31 EP EP99943982A patent/EP1117765A2/fr not_active Withdrawn
-
2001
- 2001-02-27 ZA ZA200101622A patent/ZA200101622B/xx unknown
Also Published As
Publication number | Publication date |
---|---|
WO2000012683A2 (fr) | 2000-03-09 |
WO2000012683A3 (fr) | 2000-06-29 |
AU774581B2 (en) | 2004-07-01 |
ZA200101622B (en) | 2001-09-17 |
JP2002523085A (ja) | 2002-07-30 |
EP1117765A2 (fr) | 2001-07-25 |
AU5696799A (en) | 2000-03-21 |
IL141683A0 (en) | 2002-03-10 |
WO2000012683A9 (fr) | 2000-07-27 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
FZDE | Discontinued |