CA2339639C - Programmable one-pot oligosaccharide synthesis - Google Patents

Programmable one-pot oligosaccharide synthesis Download PDF

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Publication number
CA2339639C
CA2339639C CA2339639A CA2339639A CA2339639C CA 2339639 C CA2339639 C CA 2339639C CA 2339639 A CA2339639 A CA 2339639A CA 2339639 A CA2339639 A CA 2339639A CA 2339639 C CA2339639 C CA 2339639C
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CA
Canada
Prior art keywords
glycosyl
donor
acceptors
protected
donors
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2339639A
Other languages
English (en)
French (fr)
Other versions
CA2339639A1 (en
Inventor
Chi-Huey Wong
Zhiyuan Zhang
Ian Ollmann
Timor Baasov
Xin-Shan Ye
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Scripps Research Institute
Original Assignee
Scripps Research Institute
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Scripps Research Institute filed Critical Scripps Research Institute
Publication of CA2339639A1 publication Critical patent/CA2339639A1/en
Application granted granted Critical
Publication of CA2339639C publication Critical patent/CA2339639C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
    • C07H3/06—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16C—COMPUTATIONAL CHEMISTRY; CHEMOINFORMATICS; COMPUTATIONAL MATERIALS SCIENCE
    • G16C20/00—Chemoinformatics, i.e. ICT specially adapted for the handling of physicochemical or structural data of chemical particles, elements, compounds or mixtures
    • G16C20/10—Analysis or design of chemical reactions, syntheses or processes
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16C—COMPUTATIONAL CHEMISTRY; CHEMOINFORMATICS; COMPUTATIONAL MATERIALS SCIENCE
    • G16C20/00—Chemoinformatics, i.e. ICT specially adapted for the handling of physicochemical or structural data of chemical particles, elements, compounds or mixtures
    • G16C20/90—Programming languages; Computing architectures; Database systems; Data warehousing
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Computing Systems (AREA)
  • Theoretical Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Software Systems (AREA)
  • Databases & Information Systems (AREA)
  • Analytical Chemistry (AREA)
  • Saccharide Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
CA2339639A 1998-08-10 1999-08-10 Programmable one-pot oligosaccharide synthesis Expired - Fee Related CA2339639C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US9600198P 1998-08-10 1998-08-10
US60/096,001 1998-08-10
PCT/US1999/018151 WO2000009527A1 (en) 1998-08-10 1999-08-10 Programmable one-pot oligosaccharide synthesis

Publications (2)

Publication Number Publication Date
CA2339639A1 CA2339639A1 (en) 2000-02-24
CA2339639C true CA2339639C (en) 2010-09-28

Family

ID=22254590

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2339639A Expired - Fee Related CA2339639C (en) 1998-08-10 1999-08-10 Programmable one-pot oligosaccharide synthesis

Country Status (5)

Country Link
EP (1) EP1104433A4 (ja)
JP (1) JP2002522598A (ja)
AU (1) AU773115B2 (ja)
CA (1) CA2339639C (ja)
WO (1) WO2000009527A1 (ja)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011522805A (ja) * 2008-05-30 2011-08-04 モメンタ ファーマシューティカルズ インコーポレイテッド 糖構造ならびにそのような構造を作製および使用する方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5463564A (en) * 1994-09-16 1995-10-31 3-Dimensional Pharmaceuticals, Inc. System and method of automatically generating chemical compounds with desired properties
GB9517661D0 (en) * 1995-08-30 1995-11-01 Smithkline Beecham Plc Novel compounds

Also Published As

Publication number Publication date
WO2000009527A1 (en) 2000-02-24
AU773115B2 (en) 2004-05-20
CA2339639A1 (en) 2000-02-24
EP1104433A1 (en) 2001-06-06
EP1104433A4 (en) 2005-06-15
AU5672099A (en) 2000-03-06
JP2002522598A (ja) 2002-07-23

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Effective date: 20150810