CA2336546A1 - Method for determining polynucleotide sequence variations - Google Patents

Method for determining polynucleotide sequence variations Download PDF

Info

Publication number
CA2336546A1
CA2336546A1 CA002336546A CA2336546A CA2336546A1 CA 2336546 A1 CA2336546 A1 CA 2336546A1 CA 002336546 A CA002336546 A CA 002336546A CA 2336546 A CA2336546 A CA 2336546A CA 2336546 A1 CA2336546 A1 CA 2336546A1
Authority
CA
Canada
Prior art keywords
label
terminator
primer
labeled
polynucleotide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002336546A
Other languages
English (en)
French (fr)
Inventor
John Atlas Phillips Iii
Elliott P. Dawson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BioVentures Inc
Vanderbilt University
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2336546A1 publication Critical patent/CA2336546A1/en
Abandoned legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Error Detection And Correction (AREA)
CA002336546A 1998-08-19 1999-08-19 Method for determining polynucleotide sequence variations Abandoned CA2336546A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US9713698P 1998-08-19 1998-08-19
US60/097,136 1998-08-19
PCT/US1999/018965 WO2000011221A1 (en) 1998-08-19 1999-08-19 Method for determining polynucleotide sequence variations

Publications (1)

Publication Number Publication Date
CA2336546A1 true CA2336546A1 (en) 2000-03-02

Family

ID=22261392

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002336546A Abandoned CA2336546A1 (en) 1998-08-19 1999-08-19 Method for determining polynucleotide sequence variations

Country Status (12)

Country Link
US (2) US6322988B1 (https=)
EP (1) EP1105537B1 (https=)
JP (1) JP3949378B2 (https=)
CN (1) CN1197975C (https=)
AT (1) ATE310103T1 (https=)
AU (1) AU737087C (https=)
CA (1) CA2336546A1 (https=)
DE (1) DE69928409D1 (https=)
IL (1) IL141329A (https=)
IS (1) IS5847A (https=)
WO (1) WO2000011221A1 (https=)
ZA (1) ZA200100124B (https=)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040121394A1 (en) * 1998-08-19 2004-06-24 Dawson Elliott P. Method for determining polynucleotide sequence variations
US20030138834A1 (en) * 1998-08-19 2003-07-24 Dawson Elliott P. Method for determining polynucleotide sequence variations
EP1368497A4 (en) * 2001-03-12 2007-08-15 California Inst Of Techn METHODS AND APPARATUS FOR ANALYZING ASYNCHRONOUS BASE EXTENSION POLYNUCLEOTIDE SEQUENCES
US9261460B2 (en) 2002-03-12 2016-02-16 Enzo Life Sciences, Inc. Real-time nucleic acid detection processes and compositions
EP2184369A1 (en) 2001-07-11 2010-05-12 Applied Biosystems, LLC Method for normalisation in electrophoresis
JP2005508196A (ja) 2001-11-07 2005-03-31 アプレラ コーポレイション 核酸分析の汎用ヌクレオチド
US9353405B2 (en) 2002-03-12 2016-05-31 Enzo Life Sciences, Inc. Optimized real time nucleic acid detection processes
US7189512B2 (en) * 2003-02-20 2007-03-13 Noga Porat Methods for variation detection
EP1766075B1 (en) * 2004-06-10 2010-03-17 Amersham Biosciences Corp. Method for nucleic acid analysis
EP1798291B1 (en) * 2005-12-13 2011-05-18 Institut Curie Methods and compositions for assaying mutations and/or large scale alterations in nucleic acids and their uses in diagnosis of genetic diseases and cancers
IT1397110B1 (it) * 2008-12-29 2012-12-28 St Microelectronics Rousset Microreattore autosigillante e metodo per eseguire una reazione
WO2015062184A1 (en) * 2013-11-01 2015-05-07 Accurascience, Llc Method and apparatus for calling single-nucleotide variations and other variations
CN114724628B (zh) * 2022-04-24 2022-11-08 华中农业大学 一种对多物种进行多核苷酸变异鉴定和注释的方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5683869A (en) * 1993-09-03 1997-11-04 Duke University Method of nucleic acid sequencing
WO1995034573A1 (en) * 1994-06-03 1995-12-21 Brigham And Women's Hospital Identification of polycystic kidney disease gene, diagnostics and treatment
US5830657A (en) * 1996-05-01 1998-11-03 Visible Genetics Inc. Method for single-tube sequencing of nucleic acid polymers
US6432634B1 (en) * 1996-04-18 2002-08-13 Visible Genetics Inc. Method, apparatus and kits for sequencing of nucleic acids using multiple dyes
US5847162A (en) * 1996-06-27 1998-12-08 The Perkin Elmer Corporation 4, 7-Dichlororhodamine dyes
US5928906A (en) 1996-05-09 1999-07-27 Sequenom, Inc. Process for direct sequencing during template amplification
US5846727A (en) * 1996-06-06 1998-12-08 Board Of Supervisors Of Louisiana State University And Agricultural & Mechanical College Microsystem for rapid DNA sequencing

Also Published As

Publication number Publication date
IL141329A (en) 2005-07-25
EP1105537A1 (en) 2001-06-13
US6322988B1 (en) 2001-11-27
WO2000011221A1 (en) 2000-03-02
AU5681399A (en) 2000-03-14
AU737087C (en) 2005-05-12
EP1105537A4 (en) 2002-08-14
ZA200100124B (en) 2001-08-03
DE69928409D1 (de) 2005-12-22
IL141329A0 (en) 2002-03-10
AU737087B2 (en) 2001-08-09
ATE310103T1 (de) 2005-12-15
IS5847A (is) 2001-02-16
JP2002523062A (ja) 2002-07-30
US20020164606A1 (en) 2002-11-07
CN1197975C (zh) 2005-04-20
HK1040265A1 (en) 2002-05-31
EP1105537B1 (en) 2005-11-16
CN1312859A (zh) 2001-09-12
JP3949378B2 (ja) 2007-07-25

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued