CA2335152C - Traitement de tissus animaux implantables pour l'entreposage a sec - Google Patents
Traitement de tissus animaux implantables pour l'entreposage a sec Download PDFInfo
- Publication number
- CA2335152C CA2335152C CA002335152A CA2335152A CA2335152C CA 2335152 C CA2335152 C CA 2335152C CA 002335152 A CA002335152 A CA 002335152A CA 2335152 A CA2335152 A CA 2335152A CA 2335152 C CA2335152 C CA 2335152C
- Authority
- CA
- Canada
- Prior art keywords
- tissue component
- dimensional stabilizer
- chamber
- tissue
- interstices
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
- A61L27/3691—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment characterised by physical conditions of the treatment, e.g. applying a compressive force to the composition, pressure cycles, ultrasonic/sonication or microwave treatment, lyophilisation
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/02—Preservation of living parts
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/02—Preservation of living parts
- A01N1/0205—Chemical aspects
- A01N1/021—Preservation or perfusion media, liquids, solids or gases used in the preservation of cells, tissue, organs or bodily fluids
- A01N1/0221—Freeze-process protecting agents, i.e. substances protecting cells from effects of the physical process, e.g. cryoprotectants, osmolarity regulators like oncotic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
- A61L2/0082—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using chemical substances
- A61L2/0094—Gaseous substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/02—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using physical phenomena
- A61L2/08—Radiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/16—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using chemical substances
- A61L2/20—Gaseous substances, e.g. vapours
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/16—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using chemical substances
- A61L2/20—Gaseous substances, e.g. vapours
- A61L2/206—Ethylene oxide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2202/00—Aspects relating to methods or apparatus for disinfecting or sterilising materials or objects
- A61L2202/20—Targets to be treated
- A61L2202/21—Pharmaceuticals, e.g. medicaments, artificial body parts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/40—Preparation and treatment of biological tissue for implantation, e.g. decellularisation, cross-linking
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Molecular Biology (AREA)
- Dentistry (AREA)
- Botany (AREA)
- Dermatology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- General Chemical & Material Sciences (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Materials For Medical Uses (AREA)
Abstract
L'invention concerne un procédé pour l'entreposage à sec de dispositifs à bioprothèse comprenant un composant tissulaire. Le procédé comprend les étapes suivantes: on prépare un dispositif comprenant un composant tissulaire animal réticulé chimiquement, on traite le composant tissulaire par une solution aqueuse comprenant une molécule organique hydrosoluble biocompatible, renfermant une pluralité d'atomes de carbone et une pluralité de groupes hydroxyle pendant un temps suffisant pour que l'équilibre s'établisse entre les fluides dans les interstices du composant tissulaire et la solution aqueuse, puis on stérilise le composant tissulaire traité au moyen d'un gaz stérilisant ou de rayonnement ionisant. L'invention concerne également un composant tissulaire implantable pouvant être conservé à sec. Le composant tissulaire est fixé chimiquement et renferme, dans ses interstices, un stabiliseur dimensionnel choisi dans le groupe comprenant un alcool polyhydrique et ses dérivés, un glucide hydrosoluble et une gomme hydrosoluble. Le composant tissulaire est disposé dans la chambre d'un ensemble, cette chambre étant délimitée par un ou plusieurs éléments formés d'un matériau qui est résistant à la pénétration par des micro-organismes, notamment bactéries et champignons. La chambre et le composant tissulaire sont stériles et sensiblement exempts d'une solution d'aldéhyde. A l'exception des liquides contenus dans le composant tissulaire, la chambre est également sensiblement dépourvue de liquide.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US7897098A | 1998-05-14 | 1998-05-14 | |
US09/078,970 | 1998-05-14 | ||
PCT/US1999/010680 WO1999058082A2 (fr) | 1998-05-14 | 1999-05-14 | Traitement de tissus animaux implantables pour l'entreposage a sec |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2335152A1 CA2335152A1 (fr) | 1999-11-18 |
CA2335152C true CA2335152C (fr) | 2008-11-18 |
Family
ID=22147316
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002335152A Expired - Fee Related CA2335152C (fr) | 1998-05-14 | 1999-05-14 | Traitement de tissus animaux implantables pour l'entreposage a sec |
Country Status (3)
Country | Link |
---|---|
US (1) | US6534004B2 (fr) |
CA (1) | CA2335152C (fr) |
WO (1) | WO1999058082A2 (fr) |
Families Citing this family (61)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2764514B1 (fr) | 1997-06-13 | 1999-09-03 | Biopharmex Holding Sa | Implant injectable en sous-cutane ou intradermique a bioresorbabilite controlee pour la chirurgie reparatrice ou plastique et la dermatologie esthetique |
US6878168B2 (en) | 2002-01-03 | 2005-04-12 | Edwards Lifesciences Corporation | Treatment of bioprosthetic tissues to mitigate post implantation calcification |
US8308797B2 (en) | 2002-01-04 | 2012-11-13 | Colibri Heart Valve, LLC | Percutaneously implantable replacement heart valve device and method of making same |
BR0202221A (pt) * | 2002-05-21 | 2004-04-27 | Fundacao Zerbini | Processo de tratamento de tecidos biológico |
US20060228252A1 (en) * | 2004-04-20 | 2006-10-12 | Mills C R | Process and apparatus for treating implants comprising soft tissue |
US7648676B2 (en) * | 2004-04-20 | 2010-01-19 | Rti Biologics, Inc. | Process and apparatus for treating implants comprising soft tissue |
EP1850796B1 (fr) * | 2005-02-18 | 2015-12-09 | The Cleveland Clinic Foundation | Appareil pour le remplacement d'une valvule cardiaque |
CN101146446A (zh) * | 2005-03-21 | 2008-03-19 | 3M创新有限公司 | 氟化的流体作为保存的生物标本的储存液的应用 |
WO2006113906A1 (fr) * | 2005-04-20 | 2006-10-26 | The Cleveland Clinic Foundation | Appareil et méthode de remplacement d'une valve cardiaque |
US20070074980A1 (en) * | 2005-09-02 | 2007-04-05 | Bankoski Brian R | Implant rehydration packages and methods of use |
EP2606723B1 (fr) | 2006-10-27 | 2014-06-18 | Edwards Lifesciences Corporation | Tissu biologique pour implantation chirurgicale |
WO2008089365A2 (fr) * | 2007-01-19 | 2008-07-24 | The Cleveland Clinic Foundation | Méthode de mise en place d'une valve cardiovasculaire |
US9101691B2 (en) | 2007-06-11 | 2015-08-11 | Edwards Lifesciences Corporation | Methods for pre-stressing and capping bioprosthetic tissue |
US8357387B2 (en) | 2007-12-21 | 2013-01-22 | Edwards Lifesciences Corporation | Capping bioprosthetic tissue to reduce calcification |
NZ596179A (en) * | 2009-04-29 | 2014-05-30 | Cleveland Clinic Foundation | Apparatus and method for replacing a diseased cardiac valve |
WO2011002996A2 (fr) * | 2009-07-02 | 2011-01-06 | The Cleveland Clinic Foundation | Appareil et procédé de remplacement d'une valvule cardiaque malade |
US8869982B2 (en) | 2009-12-18 | 2014-10-28 | Edwards Lifesciences Corporation | Prosthetic heart valve packaging and deployment system |
US8839957B2 (en) * | 2010-02-15 | 2014-09-23 | Michael C. Murad | Prosthetic heart valve packaging system |
EP3028672A1 (fr) | 2010-03-01 | 2016-06-08 | Colibri Heart Valve LLC | Valvule cardiaque pouvant être posée par voie percutanée et procédés associés |
AU2013204420B2 (en) * | 2010-03-01 | 2014-07-31 | Colibri Heart Valve Llc | Percutaneously deliverable heart valve and methods associated therewith |
US8679404B2 (en) * | 2010-03-05 | 2014-03-25 | Edwards Lifesciences Corporation | Dry prosthetic heart valve packaging system |
EP2656863B1 (fr) | 2010-03-23 | 2019-09-18 | Edwards Lifesciences Corporation | Procédés de conditionnement de tissus bioprothétiques en feuille |
US8906601B2 (en) | 2010-06-17 | 2014-12-09 | Edwardss Lifesciences Corporation | Methods for stabilizing a bioprosthetic tissue by chemical modification of antigenic carbohydrates |
SG186835A1 (en) | 2010-06-28 | 2013-02-28 | Colibri Heart Valve Llc | Method and apparatus for the endoluminal delivery of intravascular devices |
US9351829B2 (en) | 2010-11-17 | 2016-05-31 | Edwards Lifesciences Corporation | Double cross-linkage process to enhance post-implantation bioprosthetic tissue durability |
JP2014507179A (ja) | 2010-12-14 | 2014-03-27 | コリブリ ハート バルブ エルエルシー | 統合された弁尖を伴う折り畳まれた膜の心臓弁膜尖を含む経皮的にデリバリー可能な心臓弁 |
US9498317B2 (en) | 2010-12-16 | 2016-11-22 | Edwards Lifesciences Corporation | Prosthetic heart valve delivery systems and packaging |
US9155619B2 (en) * | 2011-02-25 | 2015-10-13 | Edwards Lifesciences Corporation | Prosthetic heart valve delivery apparatus |
US8968394B2 (en) | 2011-05-12 | 2015-03-03 | Edwards Lifesciences Corporation | Mitral heart valve holder and storage system |
CA2841573A1 (fr) * | 2011-07-11 | 2013-01-17 | The Children's Hospital Of Philadelphia | Tissus bioprothetiques resistant a l'oxydation et leur preparation |
WO2013147299A1 (fr) | 2012-03-31 | 2013-10-03 | 学校法人早稲田大学 | Tissu biologique et son procédé de traitement |
RU2665366C2 (ru) | 2012-05-11 | 2018-08-29 | АрТиАй СЕРДЖИКАЛ, ИНК. | Ксеногенные имплантаты мягких тканей и способы изготовления и использования |
US9301835B2 (en) | 2012-06-04 | 2016-04-05 | Edwards Lifesciences Corporation | Pre-assembled bioprosthetic valve and sealed conduit |
US9693862B2 (en) | 2012-07-31 | 2017-07-04 | Edwards Lifesciences Corporation | Holders for prosthetic heart valves |
US10238771B2 (en) | 2012-11-08 | 2019-03-26 | Edwards Lifesciences Corporation | Methods for treating bioprosthetic tissue using a nucleophile/electrophile in a catalytic system |
EP2967863B1 (fr) | 2013-03-15 | 2018-01-31 | Edwards Lifesciences Corporation | Conduits aortiques à valvule |
US9615922B2 (en) | 2013-09-30 | 2017-04-11 | Edwards Lifesciences Corporation | Method and apparatus for preparing a contoured biological tissue |
US10959839B2 (en) | 2013-10-08 | 2021-03-30 | Edwards Lifesciences Corporation | Method for directing cellular migration patterns on a biological tissue |
US20150122687A1 (en) | 2013-11-06 | 2015-05-07 | Edwards Lifesciences Corporation | Bioprosthetic heart valves having adaptive seals to minimize paravalvular leakage |
US10195025B2 (en) | 2014-05-12 | 2019-02-05 | Edwards Lifesciences Corporation | Prosthetic heart valve |
CN106190949B (zh) * | 2015-05-08 | 2020-04-10 | 上海微创心通医疗科技有限公司 | 一种干态动物源性胶原纤维组织材料及其制备方法和生物假体 |
US10350047B2 (en) | 2015-09-02 | 2019-07-16 | Edwards Lifesciences Corporation | Method and system for packaging and preparing a prosthetic heart valve and associated delivery system |
US10357351B2 (en) | 2015-12-04 | 2019-07-23 | Edwards Lifesciences Corporation | Storage assembly for prosthetic valve |
US20170173214A1 (en) * | 2015-12-21 | 2017-06-22 | Medtronic Vascular, Inc. | Methods for preparing dry cross-linked tissue |
WO2017189941A1 (fr) * | 2016-04-29 | 2017-11-02 | St. Jude Medical, Cardiology Division, Inc. | Procédé de traitement de tissu biologique |
CN107007887B (zh) * | 2017-02-27 | 2020-10-02 | 杭州启明医疗器械股份有限公司 | 一种交联人工生物瓣膜及其制备方法 |
WO2018160513A1 (fr) * | 2017-02-28 | 2018-09-07 | St. Jude Medical, Cardiology Division, Inc. | Tissu traité à la cellulose séché pour dosages d'activation de complément in vitro et kits de diagnostic |
US10631968B2 (en) | 2017-03-06 | 2020-04-28 | Edwards Lifesciences Corporation | Humidity-management packaging systems and methods |
WO2018167536A1 (fr) * | 2017-03-15 | 2018-09-20 | Sorin Group Italia S.R.L. | Matériau implantable et procédé de conservation |
CA3062547A1 (fr) | 2017-05-31 | 2018-12-06 | Edwards Lifesciences Corporation | Fibres de collagene et articles formes a partir desdites fibres de collagene |
EP4344679A2 (fr) | 2017-06-29 | 2024-04-03 | St. Jude Medical, Cardiology Division, Inc. | Procédé de préparation de tissu bioprothétique résistant à la calcification |
WO2019051476A1 (fr) | 2017-09-11 | 2019-03-14 | Incubar, LLC | Dispositif d'étanchéité destiné à être utilisé comme implant vasculaire de conduit pour réduire l'endofuite |
CN107802889B (zh) * | 2017-12-08 | 2019-11-01 | 上海微创心通医疗科技有限公司 | 一种干态动物源性胶原纤维组织材料及其制备方法 |
US11504231B2 (en) | 2018-05-23 | 2022-11-22 | Corcym S.R.L. | Cardiac valve prosthesis |
CN109260517B (zh) * | 2018-09-19 | 2020-10-30 | 杭州启明医疗器械股份有限公司 | 一种可预装干燥生物心脏瓣膜及其制备方法 |
WO2020092205A1 (fr) | 2018-11-01 | 2020-05-07 | Edwards Lifesciences Corporation | Valve régénérative pulmonaire transcathéter |
EP3693030A1 (fr) | 2019-02-07 | 2020-08-12 | P+F Products + Features GmbH | Procédé de préparation de tissu biologique pour implantation chirurgicale |
AU2020399770A1 (en) | 2019-12-09 | 2022-01-06 | Edwards Lifesciences Corporation | Bioprosthetic tissue preparation |
WO2021119391A1 (fr) | 2019-12-12 | 2021-06-17 | Edwards Lifesciences Corporation | Anneau d'annuloplastie hybride |
WO2024054610A1 (fr) | 2022-09-09 | 2024-03-14 | Edwards Lifesciences Corporation | Système et méthode d'emballage à sec d'une valve cardiaque |
WO2024118297A1 (fr) | 2022-11-28 | 2024-06-06 | Edwards Lifesciences Corporation | Tissu bioprothétique et traitement antimicrobien prothétique |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5336616A (en) * | 1990-09-12 | 1994-08-09 | Lifecell Corporation | Method for processing and preserving collagen-based tissues for transplantation |
US6312474B1 (en) * | 1999-09-15 | 2001-11-06 | Bio-Vascular, Inc. | Resorbable implant materials |
-
1999
- 1999-05-14 CA CA002335152A patent/CA2335152C/fr not_active Expired - Fee Related
- 1999-05-14 WO PCT/US1999/010680 patent/WO1999058082A2/fr active Application Filing
-
2000
- 2000-12-28 US US09/752,313 patent/US6534004B2/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
CA2335152A1 (fr) | 1999-11-18 |
US6534004B2 (en) | 2003-03-18 |
WO1999058082A2 (fr) | 1999-11-18 |
US20010023372A1 (en) | 2001-09-20 |
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Legal Events
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EEER | Examination request | ||
MKLA | Lapsed |