CA2328892A1 - Suppresseur de tumeur - Google Patents

Suppresseur de tumeur Download PDF

Info

Publication number
CA2328892A1
CA2328892A1 CA002328892A CA2328892A CA2328892A1 CA 2328892 A1 CA2328892 A1 CA 2328892A1 CA 002328892 A CA002328892 A CA 002328892A CA 2328892 A CA2328892 A CA 2328892A CA 2328892 A1 CA2328892 A1 CA 2328892A1
Authority
CA
Canada
Prior art keywords
tusup
polynucleotide
sequence
polypeptide
seq
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002328892A
Other languages
English (en)
Inventor
Y. Tom Tang
Neil C. Corley
Chandra Patterson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Incyte Corp
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2328892A1 publication Critical patent/CA2328892A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4738—Cell cycle regulated proteins, e.g. cyclin, CDC, INK-CCR
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C07K14/4703—Inhibitors; Suppressors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cell Biology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La présente invention concerne un suppresseur de tumeurs humain (TUSUP) et des polynucléotides qui identifient ce suppresseur (TUSUP) et codent pour ce dernier. L'invention concerne également des vecteurs d'expression, des cellules hôtes, des anticorps, des agonistes et des antagonistes ainsi que des méthodes de diagnostic, de traitement et de prévention des troubles associés avec l'expression dudit suppresseur de tumeurs.
CA002328892A 1998-05-28 1999-05-20 Suppresseur de tumeur Abandoned CA2328892A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US8635998A 1998-05-28 1998-05-28
US09/086,359 1998-05-28
PCT/US1999/011136 WO1999061612A1 (fr) 1998-05-28 1999-05-20 Suppresseur de tumeur

Publications (1)

Publication Number Publication Date
CA2328892A1 true CA2328892A1 (fr) 1999-12-02

Family

ID=22198077

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002328892A Abandoned CA2328892A1 (fr) 1998-05-28 1999-05-20 Suppresseur de tumeur

Country Status (5)

Country Link
EP (1) EP1082424A1 (fr)
JP (1) JP2002516099A (fr)
AU (1) AU4089699A (fr)
CA (1) CA2328892A1 (fr)
WO (1) WO1999061612A1 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2319668C (fr) 1998-02-03 2007-04-10 Otsuka Pharmaceutical Co., Ltd. Genes humains tsc403 et ing1l
KR100426455B1 (ko) * 2000-04-25 2004-04-13 김진우 인간 암 억제 유전자, 이에 의해 코딩되는 단백질, 이를포함하는 발현 벡터 및 이 벡터로 형질전환된 세포

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6117633A (en) * 1995-12-08 2000-09-12 University Technologies International Inc. DNA sequence encoding the tumor suppressor gene ING1
CA2319668C (fr) * 1998-02-03 2007-04-10 Otsuka Pharmaceutical Co., Ltd. Genes humains tsc403 et ing1l

Also Published As

Publication number Publication date
AU4089699A (en) 1999-12-13
WO1999061612A1 (fr) 1999-12-02
EP1082424A1 (fr) 2001-03-14
JP2002516099A (ja) 2002-06-04

Similar Documents

Publication Publication Date Title
CA2328905A1 (fr) Proteines de membrane associees a la croissance de la prostate
WO1999051640A1 (fr) Recepteur de lipoproteines de faible poids moleculaire (ldl) oxydees de l'etre humain
EP1076711A2 (fr) Proteines associees a l'apoptose humaine
US6391580B1 (en) Ras proteins
EP1095142A2 (fr) Molecules associees a une proliferation cellulaire
US5942399A (en) Amino acid permease homolog
US6080848A (en) Human brain associated protein
US20020106373A1 (en) Proteins associated with EGF signaling
CA2298766A1 (fr) Homologues proteiques d'assurance de longevite humaine
US6077693A (en) Polynucleotide encoding a promonocyte associated protein
US6071720A (en) Delayed rectifier potassium channel subunit
US6180342B1 (en) Vacuolar proton ATPase subunits
CA2328892A1 (fr) Suppresseur de tumeur
US20040086923A1 (en) Carbamoyl phosphate synthase homolog
US5846777A (en) Two cDNAs encoding WD-40 proteins
US20020192787A1 (en) Human nucleic acid methylases
US20020102708A1 (en) SH3-containing proteins
EP1080190A1 (fr) Proteine associee a la calmoduline
WO1999064593A2 (fr) Proteines de regulation du cycle cellulaire
US20020090712A1 (en) Rab proteins
WO1998044115A2 (fr) Regulateurs du processus de signalement de la proteine g
WO1999000500A1 (fr) Phosphoproteine fixatrice de calcium
WO2000005368A1 (fr) Proteines humaines de regulation du calcium
WO1999054469A1 (fr) Proteine liee au facteur de croissance des lymphocytes b
EP1097206A1 (fr) Proteines humaines de regulation du calcium

Legal Events

Date Code Title Description
FZDE Dead