CA2328138A1 - A novel method of diagnosing, monitoring, and staging lung cancer - Google Patents

A novel method of diagnosing, monitoring, and staging lung cancer Download PDF

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Publication number
CA2328138A1
CA2328138A1 CA002328138A CA2328138A CA2328138A1 CA 2328138 A1 CA2328138 A1 CA 2328138A1 CA 002328138 A CA002328138 A CA 002328138A CA 2328138 A CA2328138 A CA 2328138A CA 2328138 A1 CA2328138 A1 CA 2328138A1
Authority
CA
Canada
Prior art keywords
lsg
levels
cancer
lung
patient
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002328138A
Other languages
English (en)
French (fr)
Inventor
Fei Yang
Roberto A. Macina
Yongming Sun
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Diadexus Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2328138A1 publication Critical patent/CA2328138A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57423—Specifically defined cancers of lung
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/112—Disease subtyping, staging or classification

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pathology (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Genetics & Genomics (AREA)
  • Cell Biology (AREA)
  • Biophysics (AREA)
  • General Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CA002328138A 1998-05-21 1999-05-12 A novel method of diagnosing, monitoring, and staging lung cancer Abandoned CA2328138A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US8621298P 1998-05-21 1998-05-21
US60/086,212 1998-05-21
PCT/US1999/010344 WO1999060160A1 (en) 1998-05-21 1999-05-12 A novel method of diagnosing, monitoring, and staging lung cancer

Publications (1)

Publication Number Publication Date
CA2328138A1 true CA2328138A1 (en) 1999-11-25

Family

ID=22197037

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002328138A Abandoned CA2328138A1 (en) 1998-05-21 1999-05-12 A novel method of diagnosing, monitoring, and staging lung cancer

Country Status (4)

Country Link
EP (1) EP1082459A4 (de)
JP (1) JP3688585B2 (de)
CA (1) CA2328138A1 (de)
WO (1) WO1999060160A1 (de)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030130182A1 (en) * 1997-11-05 2003-07-10 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
US7291712B2 (en) 1998-06-25 2007-11-06 Genentech, Inc. Interleukin-8 homologous polypeptides and therapeutic uses thereof
JP3524061B2 (ja) * 1998-08-04 2004-04-26 ダイアデクスアス・インコーポレーテッド 肺がんを診断し、モニターし、病期決定し、画像化し、そして処置する新規な方法
PT1109937E (pt) * 1998-09-02 2009-02-10 Diadexus Inc Um novo método de diagnóstico, monitorização, identificação de estágio, imagiologia e tratamento de vários cancros
US20020004206A1 (en) * 1999-04-09 2002-01-10 Berger Barry M. Methods of screening for disease
US20030211510A1 (en) 1999-06-30 2003-11-13 Corixa Corporation Compositions and methods for the therapy and diagnosis of lung cancer
WO2001053349A2 (en) * 2000-01-21 2001-07-26 Ludwig Institute For Cancer Research Small cell lung cancer associated antigens and uses therefor
WO2001061055A2 (en) * 2000-02-17 2001-08-23 Diadexus, Inc. Methods for diagnosing, monitoring, staging, imaging and treating lung cancer via lung cancer specific genes
AU2001251084A1 (en) * 2000-03-29 2001-10-08 Diadexus, Inc. Polynucleotides and polypeptides as well as methods for diagnosing and treating lung cancer
WO2002008278A2 (en) * 2000-07-21 2002-01-31 Diadexus, Inc. Compositions and methods relating to lung specific genes
EP1328635A2 (de) * 2000-08-28 2003-07-23 Diadexus, Inc. Zusammensetzungen und verfahren mit bezug zu lungenspezifischen genen
WO2002077236A2 (en) * 2000-10-26 2002-10-03 Diadexus, Inc. Compositions and methods relating to lung specific genes and proteins
WO2002068633A2 (en) * 2000-11-22 2002-09-06 Diadexus, Inc. Compositions and methods relating to lung specific genes and proteins
EP1873245A1 (de) * 2001-02-28 2008-01-02 Genentech, Inc. Interleukin-8-homologe Polypeptide und ihre therapeutische Verwendung
CA2456334A1 (en) 2001-08-16 2003-02-27 The United States Of America As Represented By The Secretary Department Of Health And Human Services Molecular characteristics of non-small cell lung cancer
DE10254601A1 (de) * 2002-11-22 2004-06-03 Ganymed Pharmaceuticals Ag Differentiell in Tumoren exprimierte Genprodukte und deren Verwendung
WO2006013012A2 (en) * 2004-08-04 2006-02-09 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with napsin 1 (nap1)
US9109256B2 (en) 2004-10-27 2015-08-18 Esoterix Genetic Laboratories, Llc Method for monitoring disease progression or recurrence
EP3770278A1 (de) 2005-04-14 2021-01-27 The Trustees of Boston University Diagnose für lungenerkrankungen mittels klassenvorhersage
US9777314B2 (en) 2005-04-21 2017-10-03 Esoterix Genetic Laboratories, Llc Analysis of heterogeneous nucleic acid samples
EP2605018A1 (de) 2006-03-09 2013-06-19 The Trustees of the Boston University Diagnose- und Prognoseverfahren für Lungenerkrankungen mittels Genexpressionsprofilen aus Nasenepithelzellen
US20090186951A1 (en) 2007-09-19 2009-07-23 Brody Jerome S Identification of novel pathways for drug development for lung disease
US9495515B1 (en) 2009-12-09 2016-11-15 Veracyte, Inc. Algorithms for disease diagnostics
WO2014186036A1 (en) 2013-03-14 2014-11-20 Allegro Diagnostics Corp. Methods for evaluating copd status
US11976329B2 (en) 2013-03-15 2024-05-07 Veracyte, Inc. Methods and systems for detecting usual interstitial pneumonia
EP3770274A1 (de) 2014-11-05 2021-01-27 Veracyte, Inc. Systeme und verfahren zur diagnose von idiopathischer pulmonaler fibrose auf transbronchialen biopsien mit maschinellem lernen und hochdimensionalen transkriptionsdaten
US10927417B2 (en) 2016-07-08 2021-02-23 Trustees Of Boston University Gene expression-based biomarker for the detection and monitoring of bronchial premalignant lesions

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2221798A1 (en) * 1995-06-06 1996-12-12 Human Genome Sciences, Inc. Colon specific genes and proteins
WO1998020143A1 (en) * 1996-11-05 1998-05-14 Abbott Laboratories Reagents and methods useful for detecting diseases of the lung
JP2001522225A (ja) * 1997-01-31 2001-11-13 アボツト・ラボラトリーズ 肺の疾患の検出に有用な試薬及び方法
US6203979B1 (en) * 1998-01-16 2001-03-20 Incyte Pharmaceuticals, Inc. Human protease molecules
CA2331386A1 (en) * 1998-06-26 2000-01-06 Incyte Pharmaceuticals, Inc. Human signal peptide-containing proteins

Also Published As

Publication number Publication date
JP2002515262A (ja) 2002-05-28
WO1999060160A1 (en) 1999-11-25
EP1082459A1 (de) 2001-03-14
JP3688585B2 (ja) 2005-08-31
EP1082459A4 (de) 2002-09-25

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