CA2320624A1 - Mutants d'il-16, leurs procedes de production et d'utilisation - Google Patents
Mutants d'il-16, leurs procedes de production et d'utilisation Download PDFInfo
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- CA2320624A1 CA2320624A1 CA002320624A CA2320624A CA2320624A1 CA 2320624 A1 CA2320624 A1 CA 2320624A1 CA 002320624 A CA002320624 A CA 002320624A CA 2320624 A CA2320624 A CA 2320624A CA 2320624 A1 CA2320624 A1 CA 2320624A1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C07K14/5446—IL-16
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
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- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Toxicology (AREA)
- Genetics & Genomics (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Transplantation (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Virology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pulmonology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Abstract
L'invention porte sur un acide nucléique qui peut être utilisé pour exprimer un mutant d'IL-16 (Interleukine-16) dans une cellule hôte procaryotique ou eucaryotique. Cet acide nucléique code pour un polypeptide avec une séquence d'acides aminés commençant par les acides aminés 1 à 5 et se terminant par les acides aminés 93 à 107 du NO ID SEQ: 2, et est approprié pour produire des mutants d'IL-16 à activité améliorée.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP98101232 | 1998-01-24 | ||
| EP98101232.1 | 1998-01-24 | ||
| PCT/EP1999/000428 WO1999037781A1 (fr) | 1998-01-24 | 1999-01-22 | Mutants d'il-16, leurs procedes de production et d'utilisation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2320624A1 true CA2320624A1 (fr) | 1999-07-29 |
Family
ID=8231307
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002320624A Abandoned CA2320624A1 (fr) | 1998-01-24 | 1999-01-22 | Mutants d'il-16, leurs procedes de production et d'utilisation |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP1049782A1 (fr) |
| JP (1) | JP2002500889A (fr) |
| AU (1) | AU2424399A (fr) |
| BR (1) | BR9907216A (fr) |
| CA (1) | CA2320624A1 (fr) |
| EA (1) | EA200000769A1 (fr) |
| MX (1) | MXPA00006059A (fr) |
| WO (1) | WO1999037781A1 (fr) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6699466B1 (en) * | 1999-08-05 | 2004-03-02 | Research Corporation Technologies, Inc. | IL-16 antagonist peptides and DNA encoding the peptides |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1994028134A1 (fr) * | 1993-05-21 | 1994-12-08 | The Trustees Of Boston University | Facteur chimiotactique des lymphocytes et utilisations de celui-ci |
| WO1997023616A1 (fr) * | 1995-12-22 | 1997-07-03 | BUNDESREPUBLIK DEUTSCHLAND, vertreten durch den BUNDESMINISTER FÜR GESUNDHEIT | Polypeptide a activite d'il-16, son procede de fabrication et son utilisation |
| DE19617202A1 (de) * | 1996-04-30 | 1997-11-06 | Boehringer Mannheim Gmbh | Prozessierte Polypeptide mit IL-16-Aktivität, Verfahren zu ihrer Herstellung und Verwendung |
| US6444202B1 (en) * | 1996-11-25 | 2002-09-03 | Bundesrepublic Deutschland, Vertreten Durch Den Bundesminister Fur Gesundheit | Processed polypeptides with IL-16 activity, processes for their production and their use |
-
1999
- 1999-01-22 AU AU24243/99A patent/AU2424399A/en not_active Abandoned
- 1999-01-22 MX MXPA00006059A patent/MXPA00006059A/es unknown
- 1999-01-22 BR BR9907216-5A patent/BR9907216A/pt not_active IP Right Cessation
- 1999-01-22 JP JP2000528688A patent/JP2002500889A/ja not_active Ceased
- 1999-01-22 EA EA200000769A patent/EA200000769A1/ru unknown
- 1999-01-22 EP EP99903675A patent/EP1049782A1/fr not_active Withdrawn
- 1999-01-22 CA CA002320624A patent/CA2320624A1/fr not_active Abandoned
- 1999-01-22 WO PCT/EP1999/000428 patent/WO1999037781A1/fr not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| JP2002500889A (ja) | 2002-01-15 |
| EA200000769A1 (ru) | 2001-02-26 |
| MXPA00006059A (es) | 2003-08-01 |
| EP1049782A1 (fr) | 2000-11-08 |
| BR9907216A (pt) | 2000-10-24 |
| WO1999037781A1 (fr) | 1999-07-29 |
| AU2424399A (en) | 1999-08-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| FZDE | Discontinued |