CA2234042A1 - Nouveaux agonistes du recepteur du g-csf - Google Patents

Nouveaux agonistes du recepteur du g-csf Download PDF

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Publication number
CA2234042A1
CA2234042A1 CA002234042A CA2234042A CA2234042A1 CA 2234042 A1 CA2234042 A1 CA 2234042A1 CA 002234042 A CA002234042 A CA 002234042A CA 2234042 A CA2234042 A CA 2234042A CA 2234042 A1 CA2234042 A1 CA 2234042A1
Authority
CA
Canada
Prior art keywords
leu
ala
gln
ser
gly
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002234042A
Other languages
English (en)
Inventor
Linda L. Zurfluh
Barbara K. Klein
Charles A. Mcwherter
Yiqing Feng
John P. Mckearn
Sarah Ruth Braford-Goldberg
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GD Searle LLC
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2234042A1 publication Critical patent/CA2234042A1/fr
Abandoned legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/53—Colony-stimulating factor [CSF]
    • C07K14/535—Granulocyte CSF; Granulocyte-macrophage CSF
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La présente invention concerne des protéines agonistes du récepteur du G-CSF, des ADN codant les protéines agonistes du récepteur hématopoïétique du G-CSF, des procédés de production de protéines agonistes du récepteur hématopoïétique du G-CSF, et des procédés d'utilisation de protéines agonistes du récepteur hématopoïétique du G-CSF.
CA002234042A 1995-10-05 1996-10-04 Nouveaux agonistes du recepteur du g-csf Abandoned CA2234042A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US60/004,382 1995-09-27
US483295P 1995-10-05 1995-10-05

Publications (1)

Publication Number Publication Date
CA2234042A1 true CA2234042A1 (fr) 1997-04-10

Family

ID=21712745

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002234042A Abandoned CA2234042A1 (fr) 1995-10-05 1996-10-04 Nouveaux agonistes du recepteur du g-csf

Country Status (4)

Country Link
EP (1) EP0859843A1 (fr)
AU (1) AU717733B2 (fr)
CA (1) CA2234042A1 (fr)
WO (1) WO1997012977A1 (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5581476A (en) 1993-01-28 1996-12-03 Amgen Inc. Computer-based methods and articles of manufacture for preparing G-CSF analogs
EP1073683B1 (fr) * 1998-04-30 2005-12-28 Tanox, Inc. Anticorps agonistes pour le recepteur g-fsc et procede de criblage associe
AU6246599A (en) * 1998-09-25 2000-04-17 G.D. Searle & Co. Method of producing permuteins by scanning permutagenesis
DE19860801A1 (de) * 1998-12-30 2000-07-06 Rhein Biotech Proz & Prod Gmbh Rekombinanter Wachstumsfaktor mit der biologischen Aktivität eines G-CSF (Granulocyte Colony Stimulating Factor)
US6646110B2 (en) 2000-01-10 2003-11-11 Maxygen Holdings Ltd. G-CSF polypeptides and conjugates
US6831158B2 (en) 2000-01-10 2004-12-14 Maxygen Holdings Ltd. G-CSF conjugates
US6555660B2 (en) 2000-01-10 2003-04-29 Maxygen Holdings Ltd. G-CSF conjugates
CA2421760A1 (fr) * 2000-09-08 2002-03-14 Massachusetts Institute Of Technology Composition d'analogue du g-csf et procede associe
GB0022877D0 (en) * 2000-09-18 2000-11-01 Isis Innovation Analogues
WO2006067170A1 (fr) 2004-12-23 2006-06-29 Laboratoires Serono S.A. Polypeptides g-csf et leurs utilisations
CN101193658B (zh) 2005-06-01 2011-08-31 马克西根控股公司 聚乙二醇化g-csf多肽及其产生方法
CN107412737A (zh) 2010-01-19 2017-12-01 韩美科学株式会社 长效g‑csf缀合物的液体制剂

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0396158A1 (fr) * 1985-08-23 1990-11-07 Kirin-Amgen, Inc. Production du facteur de stimulation de colonies de granulocytes pluriactifs
ZA885101B (en) * 1987-07-17 1989-03-29 Schering Biotech Corp Human granulocyte macrophage colony stimulating factor and muteins thereof
US5635599A (en) * 1994-04-08 1997-06-03 The United States Of America As Represented By The Department Of Health And Human Services Fusion proteins comprising circularly permuted ligands

Also Published As

Publication number Publication date
EP0859843A1 (fr) 1998-08-26
AU7390096A (en) 1997-04-28
WO1997012977A1 (fr) 1997-04-10
AU717733B2 (en) 2000-03-30

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued
FZDE Discontinued

Effective date: 20081006