CA2316282A1 - Sequences d'adn regulatrices du gene de la sous-unite telomerase catalytique humaine et leur utilisation a des fins diagnostiques et therapeutiques - Google Patents
Sequences d'adn regulatrices du gene de la sous-unite telomerase catalytique humaine et leur utilisation a des fins diagnostiques et therapeutiques Download PDFInfo
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- CA2316282A1 CA2316282A1 CA002316282A CA2316282A CA2316282A1 CA 2316282 A1 CA2316282 A1 CA 2316282A1 CA 002316282 A CA002316282 A CA 002316282A CA 2316282 A CA2316282 A CA 2316282A CA 2316282 A1 CA2316282 A1 CA 2316282A1
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1241—Nucleotidyltransferases (2.7.7)
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
L'invention concerne des séquences d'ADN régulatrices, contenant des séquences promoteurs, ainsi que des séquences interposées, pour le gène de la sous-unité télomérase catalytique humaine. L'invention concerne en outre l'utilisation de ces séquences d'ADN à des fins pharmaceutiques, diagnostiques et thérapeutiques, avant tout pour traiter le cancer et le vieillissement.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE1997157984 DE19757984A1 (de) | 1997-12-24 | 1997-12-24 | Regulatorische DNA-Sequenzen aus der 5'-Region vom Gen der humanen katalytischen Telomerase-Untereinheit udn deren diagnostische und therapeutische Verwendung |
| DE19757984.1 | 1997-12-24 | ||
| PCT/EP1998/008216 WO1999033998A2 (fr) | 1997-12-24 | 1998-12-22 | Sequences d'adn regulatrices du gene de la sous-unite telomerase catalytique humaine et leur utilisation a des fins diagnostiques et therapeutiques |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2316282A1 true CA2316282A1 (fr) | 1999-07-08 |
Family
ID=7853458
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002316282A Abandoned CA2316282A1 (fr) | 1997-12-24 | 1998-12-22 | Sequences d'adn regulatrices du gene de la sous-unite telomerase catalytique humaine et leur utilisation a des fins diagnostiques et therapeutiques |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP1040195A2 (fr) |
| JP (1) | JP2003519462A (fr) |
| AU (1) | AU742489B2 (fr) |
| CA (1) | CA2316282A1 (fr) |
| DE (1) | DE19757984A1 (fr) |
| WO (1) | WO1999033998A2 (fr) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6475789B1 (en) | 1996-10-01 | 2002-11-05 | University Technology Corporation | Human telomerase catalytic subunit: diagnostic and therapeutic methods |
| US6777203B1 (en) | 1997-11-19 | 2004-08-17 | Geron Corporation | Telomerase promoter driving expression of therapeutic gene sequences |
| US7585622B1 (en) | 1996-10-01 | 2009-09-08 | Geron Corporation | Increasing the proliferative capacity of cells using telomerase reverse transcriptase |
| US6808880B2 (en) | 1996-10-01 | 2004-10-26 | Geron Corporation | Method for detecting polynucleotides encoding telomerase |
| US6261836B1 (en) | 1996-10-01 | 2001-07-17 | Geron Corporation | Telomerase |
| US6610839B1 (en) | 1997-08-14 | 2003-08-26 | Geron Corporation | Promoter for telomerase reverse transcriptase |
| ATE245194T1 (de) | 1996-10-01 | 2003-08-15 | Geron Corp | Katalytische untereinheit der menschlichen telomerase |
| US6093809A (en) | 1996-10-01 | 2000-07-25 | University Technology Corporation | Telomerase |
| US7622549B2 (en) | 1997-04-18 | 2009-11-24 | Geron Corporation | Human telomerase reverse transcriptase polypeptides |
| US7413864B2 (en) | 1997-04-18 | 2008-08-19 | Geron Corporation | Treating cancer using a telomerase vaccine |
| WO2000046355A2 (fr) * | 1999-02-04 | 2000-08-10 | Geron Corporation | Sequences de regulation transcriptionnelle de la transcriptase inverse de la telomerase |
| US7378244B2 (en) | 1997-10-01 | 2008-05-27 | Geron Corporation | Telomerase promoters sequences for screening telomerase modulators |
| DE19947668A1 (de) | 1999-10-04 | 2001-04-19 | Univ Eberhard Karls | Tumorspezifischer Vektor für die Gentherapie |
| DE10019195B4 (de) * | 2000-04-17 | 2006-03-09 | Heart Biosystems Gmbh | Reversible Immortalisierung |
| US6686159B2 (en) | 2000-08-24 | 2004-02-03 | Sierra Sciences, Inc. | Methods and compositions for modulating telomerase reverse transcriptase (TERT) expression |
| US6576464B2 (en) | 2000-11-27 | 2003-06-10 | Geron Corporation | Methods for providing differentiated stem cells |
| US6713055B2 (en) | 2000-11-27 | 2004-03-30 | Geron Corporation | Glycosyltransferase vectors for treating cancer |
| WO2003000916A2 (fr) | 2001-06-21 | 2003-01-03 | Sierra Sciences, Inc. | Proteines represseurs d'expression de la telomerase et leurs procedes d'utilisation |
| AU2002363231A1 (en) * | 2001-10-29 | 2003-05-12 | Baylor College Of Medicine | Human telomerase reverse transcriptase as a class-ii restricted tumor-associated antigen |
| US8163892B2 (en) | 2002-07-08 | 2012-04-24 | Oncolys Biopharma, Inc. | Oncolytic virus replicating selectively in tumor cells |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE245194T1 (de) * | 1996-10-01 | 2003-08-15 | Geron Corp | Katalytische untereinheit der menschlichen telomerase |
-
1997
- 1997-12-24 DE DE1997157984 patent/DE19757984A1/de not_active Withdrawn
-
1998
- 1998-12-22 WO PCT/EP1998/008216 patent/WO1999033998A2/fr not_active Application Discontinuation
- 1998-12-22 CA CA002316282A patent/CA2316282A1/fr not_active Abandoned
- 1998-12-22 JP JP2000526653A patent/JP2003519462A/ja not_active Withdrawn
- 1998-12-22 EP EP98966334A patent/EP1040195A2/fr not_active Withdrawn
- 1998-12-22 AU AU22729/99A patent/AU742489B2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| EP1040195A2 (fr) | 2000-10-04 |
| AU2272999A (en) | 1999-07-19 |
| WO1999033998A2 (fr) | 1999-07-08 |
| AU742489B2 (en) | 2002-01-03 |
| JP2003519462A (ja) | 2003-06-24 |
| DE19757984A1 (de) | 1999-07-01 |
| WO1999033998A3 (fr) | 1999-08-19 |
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