CA2316033A1 - Recombinant rhabdovirus containing a heterologous fusion protein - Google Patents
Recombinant rhabdovirus containing a heterologous fusion protein Download PDFInfo
- Publication number
- CA2316033A1 CA2316033A1 CA002316033A CA2316033A CA2316033A1 CA 2316033 A1 CA2316033 A1 CA 2316033A1 CA 002316033 A CA002316033 A CA 002316033A CA 2316033 A CA2316033 A CA 2316033A CA 2316033 A1 CA2316033 A1 CA 2316033A1
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- protein
- rhabdovirus
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- cells
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Classifications
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/20011—Rhabdoviridae
- C12N2760/20211—Vesiculovirus, e.g. vesicular stomatitis Indiana virus
- C12N2760/20222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/20011—Rhabdoviridae
- C12N2760/20211—Vesiculovirus, e.g. vesicular stomatitis Indiana virus
- C12N2760/20241—Use of virus, viral particle or viral elements as a vector
- C12N2760/20243—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2810/00—Vectors comprising a targeting moiety
- C12N2810/50—Vectors comprising as targeting moiety peptide derived from defined protein
- C12N2810/80—Vectors comprising as targeting moiety peptide derived from defined protein from vertebrates
- C12N2810/85—Vectors comprising as targeting moiety peptide derived from defined protein from vertebrates mammalian
- C12N2810/855—Vectors comprising as targeting moiety peptide derived from defined protein from vertebrates mammalian from receptors; from cell surface antigens; from cell surface determinants
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2810/00—Vectors comprising a targeting moiety
- C12N2810/50—Vectors comprising as targeting moiety peptide derived from defined protein
- C12N2810/80—Vectors comprising as targeting moiety peptide derived from defined protein from vertebrates
- C12N2810/85—Vectors comprising as targeting moiety peptide derived from defined protein from vertebrates mammalian
- C12N2810/859—Vectors comprising as targeting moiety peptide derived from defined protein from vertebrates mammalian from immunoglobulins
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2840/00—Vectors comprising a special translation-regulating system
- C12N2840/20—Vectors comprising a special translation-regulating system translation of more than one cistron
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
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- Genetics & Genomics (AREA)
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- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Zoology (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Virology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
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- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
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- General Chemical & Material Sciences (AREA)
- Plant Pathology (AREA)
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- Physics & Mathematics (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US6847297P | 1997-12-22 | 1997-12-22 | |
| US60/068,472 | 1997-12-22 | ||
| PCT/US1998/026084 WO1999032648A1 (en) | 1997-12-22 | 1998-12-22 | Recombinant rhabdovirus containing a heterologous fusion protein |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2316033A1 true CA2316033A1 (en) | 1999-07-01 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002316033A Abandoned CA2316033A1 (en) | 1997-12-22 | 1998-12-22 | Recombinant rhabdovirus containing a heterologous fusion protein |
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| Country | Link |
|---|---|
| US (2) | US6497873B1 (enExample) |
| EP (1) | EP1040198B1 (enExample) |
| JP (1) | JP4544497B2 (enExample) |
| AP (1) | AP1968A (enExample) |
| AT (1) | ATE451466T1 (enExample) |
| AU (2) | AU752004B2 (enExample) |
| BR (1) | BR9814370A (enExample) |
| CA (1) | CA2316033A1 (enExample) |
| DE (1) | DE69841372D1 (enExample) |
| IL (2) | IL136905A0 (enExample) |
| MX (1) | MXPA00006184A (enExample) |
| NZ (1) | NZ505312A (enExample) |
| OA (1) | OA11432A (enExample) |
| WO (1) | WO1999032648A1 (enExample) |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| ES2320239T3 (es) * | 1999-09-17 | 2009-05-20 | Wellstat Biologics Corporation | Virus oncolitico. |
| WO2002016437A2 (en) * | 2000-08-24 | 2002-02-28 | Thomas Jefferson University | Rhabdovirus-based vectors to express high levels of functional human antibodies |
| JP2004537279A (ja) * | 2001-03-09 | 2004-12-16 | ザ・レジェンツ・オブ・ザ・ユニバーシティ・オブ・カリフォルニア | 感染性ｃ型肝炎ウイルス合成のための細胞培養システム |
| US20030044386A1 (en) * | 2001-07-11 | 2003-03-06 | Barber Glen N. | Recombinant VSV for the treatment of tumor cells |
| US7820435B2 (en) * | 2002-02-06 | 2010-10-26 | Expression Technologies Inc. | De novo synthesized plasmid, methods of making and use thereof |
| ES2319424T3 (es) | 2003-03-27 | 2009-05-07 | Ottawa Health Research Institute | Virus mutantes de la estomatitis vesivular y sus usos. |
| US7731974B2 (en) | 2003-03-27 | 2010-06-08 | Ottawa Hospital Research Institute | Mutant vesicular stomatitis viruses and uses thereof |
| WO2005016961A1 (en) * | 2003-06-05 | 2005-02-24 | Wyeth Holdings Corporation | Immunogenic compositions comprising venezuelan equine encephalitis virus replicon vectors and paramyxovirus protein antigens |
| AU2004250129A1 (en) | 2003-06-09 | 2004-12-29 | Wyeth | Improved method for the recovery of non-segmented, negative-stranded RNA viruses from cDNA |
| EP2064229B1 (en) * | 2006-09-15 | 2015-08-12 | Ottawa Hospital Research Institute | Oncolytic rhabdovirus |
| WO2009014878A2 (en) * | 2007-07-06 | 2009-01-29 | Boyce Thompson Institute For Plant Research | Baculoviruses with enhanced virion production and a method for the production of baculoviruses |
| US8703469B2 (en) | 2007-07-06 | 2014-04-22 | Boyce Thompson Institute For Plant Research | Baculoviruses with enhanced virion production and a method for the production of baculoviruses |
| US20100215691A1 (en) * | 2009-02-20 | 2010-08-26 | Parks Christopher L | Recombinant viral vectors |
| AU2012216792A1 (en) | 2011-09-12 | 2013-03-28 | International Aids Vaccine Initiative | Immunoselection of recombinant vesicular stomatitis virus expressing HIV-1 proteins by broadly neutralizing antibodies |
| EP2586461A1 (en) | 2011-10-27 | 2013-05-01 | Christopher L. Parks | Viral particles derived from an enveloped virus |
| US9347065B2 (en) | 2012-03-29 | 2016-05-24 | International Aids Vaccine Initiative | Methods to improve vector expression and genetic stability |
| WO2013158263A1 (en) | 2012-04-18 | 2013-10-24 | Mayo Foundation For Medical Education And Research | Replication-competent vesicular stomatitis viruses |
| FR2996856B1 (fr) * | 2012-10-15 | 2015-06-05 | Agronomique Inst Nat Rech | Novirhabdovirus recombinant utilisable comme vecteur d'antigenes |
| KR20200003160A (ko) * | 2017-05-03 | 2020-01-08 | 바이오마린 파머수티컬 인크. | 조혈모세포의 형질도입을 위한 개선된 렌티바이러스 |
| IL263979B2 (en) | 2017-05-10 | 2023-09-01 | Wellstat Immuno Therapeutics Llc | Viruses with an envelope resistant to the immune system for cancer treatment |
| JP2023513135A (ja) * | 2020-02-06 | 2023-03-30 | ベーリンガー インゲルハイム フェトメディカ ゲーエムベーハー | 抗ラブドウイルス抗体を検出するのに有用なポリペプチド |
| WO2023051607A1 (zh) * | 2021-09-29 | 2023-04-06 | 上海行深生物科技有限公司 | 病毒培养方法 |
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1998
- 1998-12-22 NZ NZ505312A patent/NZ505312A/xx unknown
- 1998-12-22 AT AT98963811T patent/ATE451466T1/de not_active IP Right Cessation
- 1998-12-22 JP JP2000525566A patent/JP4544497B2/ja not_active Expired - Fee Related
- 1998-12-22 AU AU19056/99A patent/AU752004B2/en not_active Ceased
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- 1998-12-22 DE DE69841372T patent/DE69841372D1/de not_active Expired - Lifetime
- 1998-12-22 CA CA002316033A patent/CA2316033A1/en not_active Abandoned
- 1998-12-22 US US09/217,967 patent/US6497873B1/en not_active Expired - Fee Related
- 1998-12-22 WO PCT/US1998/026084 patent/WO1999032648A1/en not_active Ceased
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- 1998-12-22 AP APAP/P/2000/001852A patent/AP1968A/en active
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2000
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2002
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- 2002-10-23 US US10/277,997 patent/US20030138457A1/en not_active Abandoned
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| EP1040198B1 (en) | 2009-12-09 |
| AU1905699A (en) | 1999-07-12 |
| JP2001526901A (ja) | 2001-12-25 |
| AU752004B2 (en) | 2002-09-05 |
| AP1968A (en) | 2009-04-30 |
| WO1999032648A1 (en) | 1999-07-01 |
| AP2000001852A0 (en) | 2000-06-30 |
| US6497873B1 (en) | 2002-12-24 |
| NZ505312A (en) | 2003-01-31 |
| US20030138457A1 (en) | 2003-07-24 |
| MXPA00006184A (es) | 2003-02-11 |
| ATE451466T1 (de) | 2009-12-15 |
| DE69841372D1 (de) | 2010-01-21 |
| AU2002300207B2 (en) | 2006-07-13 |
| IL136905A (en) | 2007-10-31 |
| BR9814370A (pt) | 2000-10-10 |
| EP1040198A1 (en) | 2000-10-04 |
| OA11432A (en) | 2004-04-26 |
| JP4544497B2 (ja) | 2010-09-15 |
| IL136905A0 (en) | 2001-06-14 |
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| EEER | Examination request | ||
| FZDE | Discontinued |