CA2315273A1 - Molecules d'adn codant le recepteur proteique nucleaire nnr4 de vertebres - Google Patents

Molecules d'adn codant le recepteur proteique nucleaire nnr4 de vertebres Download PDF

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Publication number
CA2315273A1
CA2315273A1 CA002315273A CA2315273A CA2315273A1 CA 2315273 A1 CA2315273 A1 CA 2315273A1 CA 002315273 A CA002315273 A CA 002315273A CA 2315273 A CA2315273 A CA 2315273A CA 2315273 A1 CA2315273 A1 CA 2315273A1
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CA
Canada
Prior art keywords
nnr4
protein
expression vector
host cell
recombinant
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002315273A
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English (en)
Inventor
Fang Chen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2315273A1 publication Critical patent/CA2315273A1/fr
Abandoned legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70567Nuclear receptors, e.g. retinoic acid receptor [RAR], RXR, nuclear orphan receptors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

La présente invention concerne l'isolement et la caractérisation de molécules d'ADNc codant un nouveau membre de la superfamille des récepteurs nucléaires humains, à savoir nNR4. L'invention concerne également des vecteurs recombinés, des cellules hôtes recombinées, des méthodes de criblage de modulateurs de l'activité de nNR4, et la production d'anticorps contre nNR4, ou d'épitopes de ces anticorps.
CA002315273A 1997-12-12 1998-12-11 Molecules d'adn codant le recepteur proteique nucleaire nnr4 de vertebres Abandoned CA2315273A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US6814497P 1997-12-12 1997-12-12
US60/068,144 1997-12-12
PCT/US1998/026446 WO1999029722A1 (fr) 1997-12-12 1998-12-11 MOLECULES D'ADN CODANT LE RECEPTEUR PROTEIQUE NUCLEAIRE nNR4 DE VERTEBRES

Publications (1)

Publication Number Publication Date
CA2315273A1 true CA2315273A1 (fr) 1999-06-17

Family

ID=22080682

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002315273A Abandoned CA2315273A1 (fr) 1997-12-12 1998-12-11 Molecules d'adn codant le recepteur proteique nucleaire nnr4 de vertebres

Country Status (4)

Country Link
EP (1) EP1037912A1 (fr)
JP (1) JP2001525196A (fr)
CA (1) CA2315273A1 (fr)
WO (1) WO1999029722A1 (fr)

Also Published As

Publication number Publication date
EP1037912A1 (fr) 2000-09-27
JP2001525196A (ja) 2001-12-11
WO1999029722A1 (fr) 1999-06-17

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Legal Events

Date Code Title Description
FZDE Discontinued