CA2314611A1 - Nouveau candida albicans kre9 et ses utilisations - Google Patents
Nouveau candida albicans kre9 et ses utilisations Download PDFInfo
- Publication number
- CA2314611A1 CA2314611A1 CA002314611A CA2314611A CA2314611A1 CA 2314611 A1 CA2314611 A1 CA 2314611A1 CA 002314611 A CA002314611 A CA 002314611A CA 2314611 A CA2314611 A CA 2314611A CA 2314611 A1 CA2314611 A1 CA 2314611A1
- Authority
- CA
- Canada
- Prior art keywords
- cakre9
- gene
- thr
- glucan
- kre9
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
- C12Q1/6895—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for plants, fungi or algae
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/37—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
- C07K14/39—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from yeasts
- C07K14/40—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from yeasts from Candida
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Mycology (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Botany (AREA)
- Physics & Mathematics (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
L'invention concerne un ADN isolé codant pour un gène essentiel à la synthèse de glucane de la paroi cellulaire de Candida albicans, ce gène étant désigné CaKRE9, la séquence de cet ADN étant illustrée par la figure 1. Elle concerne des méthodes de criblage antifongique in vitro et in vivo servant à identifier des composés inhibant la synthèse, l'assemblage et/ou la régulation de .beta.1,6-glucane. Elle concerne également un procédé in vitro servant à diagnostiquer des maladies provoquées par une infection fongique chez un malade.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA002314611A CA2314611A1 (fr) | 1997-12-12 | 1998-12-10 | Nouveau candida albicans kre9 et ses utilisations |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA2,218,446 | 1997-12-12 | ||
CA002218446A CA2218446A1 (fr) | 1997-12-12 | 1997-12-12 | Nouveau candida albicans kre9 et applications |
PCT/CA1998/001151 WO1999031269A2 (fr) | 1997-12-12 | 1998-12-10 | Nouveau candida albicans kre9 et ses utilisations |
CA002314611A CA2314611A1 (fr) | 1997-12-12 | 1998-12-10 | Nouveau candida albicans kre9 et ses utilisations |
Publications (1)
Publication Number | Publication Date |
---|---|
CA2314611A1 true CA2314611A1 (fr) | 1999-06-24 |
Family
ID=25679731
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002314611A Abandoned CA2314611A1 (fr) | 1997-12-12 | 1998-12-10 | Nouveau candida albicans kre9 et ses utilisations |
Country Status (1)
Country | Link |
---|---|
CA (1) | CA2314611A1 (fr) |
-
1998
- 1998-12-10 CA CA002314611A patent/CA2314611A1/fr not_active Abandoned
Similar Documents
Publication | Publication Date | Title |
---|---|---|
Martinez-Lopez et al. | The GPI-anchored protein CaEcm33p is required for cell wall integrity, morphogenesis and virulence in Candida albicans | |
Bulawa | Genetics and molecular biology of chitin synthesis in fungi | |
Nakano et al. | The small GTP‐binding protein Rho1 is a multifunctional protein that regulates actin localization, cell polarity, and septum formation in the fission yeast Schizosaccharomyces pombe | |
Yue et al. | The STE12α homolog is required for haploid filamentation but largely dispensable for mating and virulence in Cryptococcus neoformans | |
Gu et al. | Protein kinase FgSch 9 serves as a mediator of the target of rapamycin and high osmolarity glycerol pathways and regulates multiple stress responses and secondary metabolism in F usarium graminearum | |
Jiang et al. | CWH41 encodes a novel endoplasmic reticulum membrane N-glycoprotein involved in beta 1, 6-glucan assembly | |
US6582911B1 (en) | Candida albicans KRE9 and uses thereof | |
KR20010032245A (ko) | 균류의 유전자 발현의 조절 | |
Monod et al. | Secreted proteinases and other virulence mechanisms of Candida albicans | |
JP2001513622A (ja) | 抗菌剤の同定のためのアッセイおよび試薬、並びにそれらに関連する利用 | |
Xu et al. | Genetical and O-glycoproteomic analyses reveal the roles of three protein O-mannosyltransferases in phytopathogen Fusarium oxysporum f. sp. cucumerinum | |
Hsueh et al. | A homolog of Ste6, the a-factor transporter in Saccharomyces cerevisiae, is required for mating but not for monokaryotic fruiting in Cryptococcus neoformans | |
Ma et al. | BsTup1 is required for growth, conidiogenesis, stress response and pathogenicity of Bipolaris sorokiniana | |
Kim et al. | Subunits of the vacuolar H+-ATPase complex, Vma4 and Vma10, are essential for virulence and represent potential drug targets in Candida albicans | |
KR20020097180A (ko) | 약물 표적 발견을 위한 유전자 분열 방법 | |
Atanasova et al. | The GPI-anchored GH76 protein Dfg5 affects hyphal morphology and osmoregulation in the mycoparasite Trichoderma atroviride and is interconnected with MAPK signaling | |
WO1998057978A1 (fr) | Procedes et compositions pour la purification rapide de proteasomes et procedes d'utilisation des composants de ces proteasomes | |
CA2314611A1 (fr) | Nouveau candida albicans kre9 et ses utilisations | |
JP4842440B2 (ja) | カンジダ・アルビカンス(Candida albicans)必須真菌特異的遺伝子の同定および抗真菌薬剤の発見におけるそれらの使用 | |
EP0678578A2 (fr) | Gène de la résistance multiple aux drogues d'auréobasidium pullulans | |
US6153376A (en) | Screening using S. cerevisiae mannosyltransferase encoding genes | |
WO2000039342A2 (fr) | UTILISATION DE GENES ET DE POLYPEPTIDES ESSENTIELS DE $i(SACCHAROMYCES) | |
US5691187A (en) | Anti-fungal agents and methods of identifying and using the same | |
WO1998044148A1 (fr) | Dosage d'histidine kinase | |
Köhler | Specific ubiquitin-dependent protein degradation requires a trimeric CandA complex in Aspergillus nidulans |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
FZDE | Discontinued |