CA2309604C - Compositions and methods for targeted delivery of factors - Google Patents
Compositions and methods for targeted delivery of factors Download PDFInfo
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- CA2309604C CA2309604C CA002309604A CA2309604A CA2309604C CA 2309604 C CA2309604 C CA 2309604C CA 002309604 A CA002309604 A CA 002309604A CA 2309604 A CA2309604 A CA 2309604A CA 2309604 C CA2309604 C CA 2309604C
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- 229910001415 sodium ion Inorganic materials 0.000 description 1
- 235000010339 sodium tetraborate Nutrition 0.000 description 1
- 230000009576 somatic growth Effects 0.000 description 1
- 229960004954 sparfloxacin Drugs 0.000 description 1
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- SEEPANYCNGTZFQ-UHFFFAOYSA-N sulfadiazine Chemical compound C1=CC(N)=CC=C1S(=O)(=O)NC1=NC=CC=N1 SEEPANYCNGTZFQ-UHFFFAOYSA-N 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
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- 229960002180 tetracycline Drugs 0.000 description 1
- 229930101283 tetracycline Natural products 0.000 description 1
- 235000019364 tetracycline Nutrition 0.000 description 1
- 150000003522 tetracyclines Chemical class 0.000 description 1
- 229940126585 therapeutic drug Drugs 0.000 description 1
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- 238000002054 transplantation Methods 0.000 description 1
- 230000007723 transport mechanism Effects 0.000 description 1
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
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- BSVBQGMMJUBVOD-UHFFFAOYSA-N trisodium borate Chemical compound [Na+].[Na+].[Na+].[O-]B([O-])[O-] BSVBQGMMJUBVOD-UHFFFAOYSA-N 0.000 description 1
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- 230000003827 upregulation Effects 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/241—Tumor Necrosis Factors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55505—Inorganic adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55516—Proteins; Peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55522—Cytokines; Lymphokines; Interferons
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/77—Internalization into the cell
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Oncology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Biochemistry (AREA)
- Communicable Diseases (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Virology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/966,940 US6274552B1 (en) | 1993-03-18 | 1997-11-10 | Composition and method for delivery of biologically-active factors |
| US7581198P | 1998-02-24 | 1998-02-24 | |
| US60/075,811 | 1998-02-24 | ||
| US8669698P | 1998-05-26 | 1998-05-26 | |
| US10745598P | 1998-11-06 | 1998-11-06 | |
| US08/966,940 | 1998-11-06 | ||
| US60/086,696 | 1998-11-06 | ||
| US60/107,455 | 1998-11-06 | ||
| PCT/US1998/023931 WO1999024077A2 (en) | 1997-11-10 | 1998-11-10 | Compositions and methods for targeted delivery of biologically-active factors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2309604A1 CA2309604A1 (en) | 1999-05-20 |
| CA2309604C true CA2309604C (en) | 2010-01-12 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002309604A Expired - Fee Related CA2309604C (en) | 1997-11-10 | 1998-11-10 | Compositions and methods for targeted delivery of factors |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20090035265A1 (enExample) |
| EP (1) | EP1044022B1 (enExample) |
| JP (1) | JP4620243B2 (enExample) |
| AT (1) | ATE320270T1 (enExample) |
| AU (1) | AU760035B2 (enExample) |
| CA (1) | CA2309604C (enExample) |
| DE (1) | DE69833876T2 (enExample) |
| NZ (1) | NZ504291A (enExample) |
| WO (1) | WO1999024077A2 (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20010055581A1 (en) | 1994-03-18 | 2001-12-27 | Lawrence Tamarkin | Composition and method for delivery of biologically-active factors |
| WO1999024066A2 (en) * | 1997-11-10 | 1999-05-20 | Cytimmune Sciences, Inc. | Methods and compositions for enhancing immune response and for the production of in vitro mabs |
| US6407218B1 (en) | 1997-11-10 | 2002-06-18 | Cytimmune Sciences, Inc. | Method and compositions for enhancing immune response and for the production of in vitro mabs |
| US7229841B2 (en) | 2001-04-30 | 2007-06-12 | Cytimmune Sciences, Inc. | Colloidal metal compositions and methods |
| JP2009286808A (ja) * | 1997-11-10 | 2009-12-10 | Cytimmune Sciences Inc | 生物学的に活性な因子の標的化された送達のための組成物および方法 |
| CA2448607C (en) | 2001-04-30 | 2013-01-22 | Cytimmune Sciences, Inc. | Colloidal metal compositions and methods |
| EP1694301A4 (en) * | 2003-12-02 | 2009-11-18 | Cytimmune Sciences Inc | METHOD AND COMPOSITIONS FOR THE PRODUCTION OF MONOCLONAL ANTIBODIES |
| GB0417487D0 (en) | 2004-08-05 | 2004-09-08 | Novartis Ag | Organic compound |
| US8877156B2 (en) | 2007-06-26 | 2014-11-04 | New York University | Contrast agents anchored by thiols on nanoparticles |
| EP2200932A4 (en) * | 2007-09-21 | 2014-09-10 | Cytimmune Sciences Inc | NANOTHERAPEUTIC COLLOIDAL METAL COMPOSITIONS AND METHODS |
| EP2219458B1 (en) | 2007-11-08 | 2015-07-15 | Cytimmune Sciences, Inc. | Compositions and methods for generating antibodies |
| WO2009140408A2 (en) | 2008-05-13 | 2009-11-19 | University Of Kansas | Metal abstraction peptide (map) tag and associated methods |
| WO2013181461A2 (en) | 2012-06-01 | 2013-12-05 | University Of Kansas | Metal abstraction peptide with superoxide dismutase activity |
| US10064940B2 (en) | 2013-12-11 | 2018-09-04 | Siva Therapeutics Inc. | Multifunctional radiation delivery apparatus and method |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4963354A (en) * | 1987-01-21 | 1990-10-16 | Genentech, Inc. | Use of tumor necrosis factor (TNF) as an adjuvant |
| US5047523A (en) * | 1988-08-02 | 1991-09-10 | Ortho Diagnostic Systems Inc. | Nucleic acid probe for detection of neisseria gonorrhoea |
| US5248772A (en) * | 1992-01-29 | 1993-09-28 | Coulter Corporation | Formation of colloidal metal dispersions using aminodextrans as reductants and protective agents |
| CA2158475C (en) * | 1993-03-18 | 2009-06-02 | Lawrence Tamarkin | Composition and method for reducing toxicity of biologically-active factors |
| JPH07227299A (ja) * | 1994-02-14 | 1995-08-29 | Kyoto Daiichi Kagaku:Kk | Ｄｎａの特定塩基配列の検出方法及びその装置 |
| US5521289A (en) * | 1994-07-29 | 1996-05-28 | Nanoprobes, Inc. | Small organometallic probes |
| US5686578A (en) * | 1994-08-05 | 1997-11-11 | Immunomedics, Inc. | Polyspecific immunoconjugates and antibody composites for targeting the multidrug resistant phenotype |
| WO1996040245A1 (en) * | 1995-06-07 | 1996-12-19 | Immunomedics, Inc. | Improved delivery of diagnostic and therapeutic agents to a target site |
| AU2610097A (en) * | 1996-04-10 | 1997-10-29 | Sangstat Medical Corporation | Cytomodulating conjugates of members of specific binding pairs |
| DE19622628A1 (de) * | 1996-06-05 | 1997-12-11 | Boehringer Mannheim Gmbh | Stabilisierung von Metallkonjugaten |
| US6294378B1 (en) * | 1996-07-26 | 2001-09-25 | Sloan-Kettering Institute For Cancer Research | Method and reagents for genetic immunization |
| US6395276B1 (en) * | 1997-05-02 | 2002-05-28 | Immunomedics, Inc. | Immunotoxins directed against malignant cells |
| DE19726186A1 (de) * | 1997-06-20 | 1998-12-24 | Boehringer Ingelheim Int | Komplexe für den Transport von Nukleinsäure in höhere eukaryotische Zellen |
| WO2005072893A1 (en) * | 2004-01-28 | 2005-08-11 | Cytimmune Sciences, Inc. | Functionalized colloidal metal compositions and methods |
| US20060185027A1 (en) * | 2004-12-23 | 2006-08-17 | David Bartel | Systems and methods for identifying miRNA targets and for altering miRNA and target expression |
-
1998
- 1998-11-10 AU AU13940/99A patent/AU760035B2/en not_active Ceased
- 1998-11-10 EP EP98957757A patent/EP1044022B1/en not_active Expired - Lifetime
- 1998-11-10 WO PCT/US1998/023931 patent/WO1999024077A2/en not_active Ceased
- 1998-11-10 JP JP2000520162A patent/JP4620243B2/ja not_active Expired - Fee Related
- 1998-11-10 DE DE69833876T patent/DE69833876T2/de not_active Expired - Lifetime
- 1998-11-10 AT AT98957757T patent/ATE320270T1/de active
- 1998-11-10 CA CA002309604A patent/CA2309604C/en not_active Expired - Fee Related
- 1998-11-10 NZ NZ504291A patent/NZ504291A/xx not_active IP Right Cessation
-
2008
- 2008-10-13 US US12/250,126 patent/US20090035265A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| ATE320270T1 (de) | 2006-04-15 |
| AU760035B2 (en) | 2003-05-08 |
| EP1044022B1 (en) | 2006-03-15 |
| AU1394099A (en) | 1999-05-31 |
| JP4620243B2 (ja) | 2011-01-26 |
| WO1999024077A3 (en) | 1999-10-07 |
| EP1044022A2 (en) | 2000-10-18 |
| CA2309604A1 (en) | 1999-05-20 |
| NZ504291A (en) | 2002-10-25 |
| DE69833876D1 (de) | 2006-05-11 |
| WO1999024077A2 (en) | 1999-05-20 |
| DE69833876T2 (de) | 2007-05-24 |
| US20090035265A1 (en) | 2009-02-05 |
| JP2001522818A (ja) | 2001-11-20 |
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| Date | Code | Title | Description |
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| EEER | Examination request | ||
| MKLA | Lapsed |
Effective date: 20151110 |