CA2309518A1 - Apoptotic entities for use in treatment of t-cell-mediated and inflammatory disorders - Google Patents
Apoptotic entities for use in treatment of t-cell-mediated and inflammatory disorders Download PDFInfo
- Publication number
- CA2309518A1 CA2309518A1 CA 2309518 CA2309518A CA2309518A1 CA 2309518 A1 CA2309518 A1 CA 2309518A1 CA 2309518 CA2309518 CA 2309518 CA 2309518 A CA2309518 A CA 2309518A CA 2309518 A1 CA2309518 A1 CA 2309518A1
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- Prior art keywords
- cells
- apoptotic
- cell
- patient
- treatment
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- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A61K40/00—Cellular immunotherapy
- A61K40/10—Cellular immunotherapy characterised by the cell type used
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/20—Cellular immunotherapy characterised by the effect or the function of the cells
- A61K40/22—Immunosuppressive or immunotolerising
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
- A61K40/41—Vertebrate antigens
- A61K40/416—Antigens related to auto-immune diseases; Preparations to induce self-tolerance
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/06—Antiabortive agents; Labour repressants
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- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
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- A61P17/06—Antipsoriatics
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
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- A—HUMAN NECESSITIES
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- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
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- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Dermatology (AREA)
- Diabetes (AREA)
- Neurosurgery (AREA)
- Endocrinology (AREA)
- Rheumatology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Emergency Medicine (AREA)
- Vascular Medicine (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Urology & Nephrology (AREA)
- Gynecology & Obstetrics (AREA)
- Pregnancy & Childbirth (AREA)
- Reproductive Health (AREA)
- Transplantation (AREA)
Priority Applications (14)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA 2309518 CA2309518A1 (en) | 2000-05-25 | 2000-05-25 | Apoptotic entities for use in treatment of t-cell-mediated and inflammatory disorders |
| EP20050025962 EP1669081A1 (en) | 2000-05-25 | 2001-05-25 | Apoptotic entities for use in treatment of T-cell-mediated und inflammatory disorders |
| DK01935896T DK1289534T3 (da) | 2000-05-25 | 2001-05-25 | Apoptotiske enheder til anvendelse ved behandling af T-cellemedierede og inflammatoriske lidelser |
| CA002409960A CA2409960A1 (en) | 2000-05-25 | 2001-05-25 | Apoptotic entities for use in treatment of t-cell-mediated and inflammatory disorders |
| AT01935896T ATE311191T1 (de) | 2000-05-25 | 2001-05-25 | Apoptotische körper zur verwendung in der behandlung von t-zell-vermittelten- und entzündungserkrankungen |
| PCT/CA2001/000758 WO2001089536A2 (en) | 2000-05-25 | 2001-05-25 | Apoptotic entities for use in treatment of t-cell-mediated and inflammatory disorders |
| HK03106460.5A HK1055079B (en) | 2000-05-25 | 2001-05-25 | Apoptotic entities for use in treatment of t-cell-mediated and inflammatory disorders |
| AU2001261986A AU2001261986A1 (en) | 2000-05-25 | 2001-05-25 | Apoptotic entities for use in treatment of t-cell-mediated and inflammatory disorders |
| US09/866,488 US20020051771A1 (en) | 2000-05-25 | 2001-05-25 | Apoptotic entities for use in treatment of T-cell-mediated and inflammatory disorders |
| DE2001615432 DE60115432T2 (de) | 2000-05-25 | 2001-05-25 | Apoptotische körper zur verwendung in der behandlung von t-zell-vermittelten- und entzündungserkrankungen |
| JP2001585780A JP2003534281A (ja) | 2000-05-25 | 2001-05-25 | Ｔ細胞媒介性及び炎症性疾患の治療における使用のためのアポトーシス体 |
| EP01935896A EP1289534B1 (en) | 2000-05-25 | 2001-05-25 | Apoptotic entities for use in treatment of t-cell-mediated and inflammatory disorders |
| ES01935896T ES2254424T3 (es) | 2000-05-25 | 2001-05-25 | Entidades adoptoticas que se utilizan en el tratamiento de trastornos inflamatorios en los que intervienen celulas t. |
| TW90113342A TWI249404B (en) | 2000-05-25 | 2001-06-01 | Apoptotic entities for use in treatment of T-cell-mediated and inflammatory disorders |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA 2309518 CA2309518A1 (en) | 2000-05-25 | 2000-05-25 | Apoptotic entities for use in treatment of t-cell-mediated and inflammatory disorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2309518A1 true CA2309518A1 (en) | 2001-11-25 |
Family
ID=4166254
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA 2309518 Abandoned CA2309518A1 (en) | 2000-05-25 | 2000-05-25 | Apoptotic entities for use in treatment of t-cell-mediated and inflammatory disorders |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20020051771A1 (enExample) |
| EP (2) | EP1669081A1 (enExample) |
| JP (1) | JP2003534281A (enExample) |
| AT (1) | ATE311191T1 (enExample) |
| AU (1) | AU2001261986A1 (enExample) |
| CA (1) | CA2309518A1 (enExample) |
| DE (1) | DE60115432T2 (enExample) |
| DK (1) | DK1289534T3 (enExample) |
| ES (1) | ES2254424T3 (enExample) |
| TW (1) | TWI249404B (enExample) |
| WO (1) | WO2001089536A2 (enExample) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2309424A1 (en) * | 2000-05-25 | 2001-11-25 | Vasogen Ireland Limited | Apoptotic entities for use in treatment of neurodegenerative and other neurological disorders |
| CA2327631A1 (en) * | 2000-12-05 | 2002-06-05 | Vasogen Ireland Limited | Inflammatory cytokine secretion inhibition |
| US7727523B2 (en) * | 2001-08-13 | 2010-06-01 | Yale University | Method for suppressing immune system response to transplanted tissue or cells |
| WO2003015850A1 (en) * | 2001-08-13 | 2003-02-27 | Edelson Richard Leslie | Method for inducing selectively suppressed immune response |
| EP1469733A4 (en) * | 2001-11-29 | 2008-07-23 | Therakos Inc | METHOD FOR PRE-TREATING A PATIENT WITH EXTRACORPORAL PHOTOPHERESIS AND / OR APOPTOTIC CELLS |
| US8524495B2 (en) | 2007-05-16 | 2013-09-03 | Yale University | Methods for inducing the differentiation of blood monocytes into functional dendritic cells |
| JP6483023B2 (ja) * | 2012-12-06 | 2019-03-13 | エンリヴェックス セラピューティクス リミテッド | 治療用アポトーシス細胞調製物、その製造方法及びその使用 |
| US11512289B2 (en) * | 2015-02-18 | 2022-11-29 | Enlivex Therapeutics Rdo Ltd | Combination immune therapy and cytokine control therapy for cancer treatment |
| US11000548B2 (en) | 2015-02-18 | 2021-05-11 | Enlivex Therapeutics Ltd | Combination immune therapy and cytokine control therapy for cancer treatment |
| US11497767B2 (en) | 2015-02-18 | 2022-11-15 | Enlivex Therapeutics R&D Ltd | Combination immune therapy and cytokine control therapy for cancer treatment |
| US11304976B2 (en) | 2015-02-18 | 2022-04-19 | Enlivex Therapeutics Ltd | Combination immune therapy and cytokine control therapy for cancer treatment |
| US11318163B2 (en) | 2015-02-18 | 2022-05-03 | Enlivex Therapeutics Ltd | Combination immune therapy and cytokine control therapy for cancer treatment |
| US11596652B2 (en) | 2015-02-18 | 2023-03-07 | Enlivex Therapeutics R&D Ltd | Early apoptotic cells for use in treating sepsis |
| US10857181B2 (en) | 2015-04-21 | 2020-12-08 | Enlivex Therapeutics Ltd | Therapeutic pooled blood apoptotic cell preparations and uses thereof |
| CA3014885A1 (en) * | 2016-02-18 | 2017-08-24 | Enlivex Therapeutics Ltd. | Combination immune therapy and cytokine control therapy for cancer treatment |
| WO2023209709A1 (en) * | 2022-04-27 | 2023-11-02 | Enlivex Therapeutics Rdo Ltd | Apoptotic cell - chemotherapy combination therapy |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5980954A (en) * | 1992-02-07 | 1999-11-09 | Vasogen Ireland Limited | Treatment of autoimmune diseases |
| CA2309424A1 (en) * | 2000-05-25 | 2001-11-25 | Vasogen Ireland Limited | Apoptotic entities for use in treatment of neurodegenerative and other neurological disorders |
| CA2309417A1 (en) * | 2000-05-25 | 2001-11-25 | Anthony E. Bolton | Apoptotic entities for use in treatment of endothelium dysfunction disorders |
| EP1469733A4 (en) * | 2001-11-29 | 2008-07-23 | Therakos Inc | METHOD FOR PRE-TREATING A PATIENT WITH EXTRACORPORAL PHOTOPHERESIS AND / OR APOPTOTIC CELLS |
-
2000
- 2000-05-25 CA CA 2309518 patent/CA2309518A1/en not_active Abandoned
-
2001
- 2001-05-25 DK DK01935896T patent/DK1289534T3/da active
- 2001-05-25 DE DE2001615432 patent/DE60115432T2/de not_active Expired - Fee Related
- 2001-05-25 JP JP2001585780A patent/JP2003534281A/ja not_active Withdrawn
- 2001-05-25 AU AU2001261986A patent/AU2001261986A1/en not_active Abandoned
- 2001-05-25 ES ES01935896T patent/ES2254424T3/es not_active Expired - Lifetime
- 2001-05-25 US US09/866,488 patent/US20020051771A1/en not_active Abandoned
- 2001-05-25 WO PCT/CA2001/000758 patent/WO2001089536A2/en not_active Ceased
- 2001-05-25 AT AT01935896T patent/ATE311191T1/de not_active IP Right Cessation
- 2001-05-25 EP EP20050025962 patent/EP1669081A1/en not_active Withdrawn
- 2001-05-25 EP EP01935896A patent/EP1289534B1/en not_active Expired - Lifetime
- 2001-06-01 TW TW90113342A patent/TWI249404B/zh not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| AU2001261986A1 (en) | 2001-12-03 |
| WO2001089536A2 (en) | 2001-11-29 |
| WO2001089536A3 (en) | 2002-08-01 |
| ES2254424T3 (es) | 2006-06-16 |
| TWI249404B (en) | 2006-02-21 |
| DK1289534T3 (da) | 2006-03-20 |
| HK1055079A1 (en) | 2003-12-24 |
| EP1289534A2 (en) | 2003-03-12 |
| EP1669081A1 (en) | 2006-06-14 |
| DE60115432D1 (de) | 2006-01-05 |
| US20020051771A1 (en) | 2002-05-02 |
| EP1289534B1 (en) | 2005-11-30 |
| JP2003534281A (ja) | 2003-11-18 |
| ATE311191T1 (de) | 2005-12-15 |
| DE60115432T2 (de) | 2006-08-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Discontinued |