CA2305528A1 - Methods and compositions for reducing bacterial tolerance of disinfectants and organic solvents - Google Patents
Methods and compositions for reducing bacterial tolerance of disinfectants and organic solvents Download PDFInfo
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- CA2305528A1 CA2305528A1 CA002305528A CA2305528A CA2305528A1 CA 2305528 A1 CA2305528 A1 CA 2305528A1 CA 002305528 A CA002305528 A CA 002305528A CA 2305528 A CA2305528 A CA 2305528A CA 2305528 A1 CA2305528 A1 CA 2305528A1
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- 239000004067 bulking agent Substances 0.000 description 1
- 150000004657 carbamic acid derivatives Chemical class 0.000 description 1
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- 239000012895 dilution Substances 0.000 description 1
- SWSQBOPZIKWTGO-UHFFFAOYSA-N dimethylaminoamidine Natural products CN(C)C(N)=N SWSQBOPZIKWTGO-UHFFFAOYSA-N 0.000 description 1
- NAGJZTKCGNOGPW-UHFFFAOYSA-N dithiophosphoric acid Chemical class OP(O)(S)=S NAGJZTKCGNOGPW-UHFFFAOYSA-N 0.000 description 1
- 229960001484 edetic acid Drugs 0.000 description 1
- 238000001952 enzyme assay Methods 0.000 description 1
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- 239000013604 expression vector Substances 0.000 description 1
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- 238000001502 gel electrophoresis Methods 0.000 description 1
- 102000034356 gene-regulatory proteins Human genes 0.000 description 1
- 108091006104 gene-regulatory proteins Proteins 0.000 description 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 238000001727 in vivo Methods 0.000 description 1
- 238000011534 incubation Methods 0.000 description 1
- 230000003834 intracellular effect Effects 0.000 description 1
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- 230000006506 pH homeostasis Effects 0.000 description 1
- 150000002960 penicillins Chemical class 0.000 description 1
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- 125000002467 phosphate group Chemical group [H]OP(=O)(O[H])O[*] 0.000 description 1
- 150000008298 phosphoramidates Chemical class 0.000 description 1
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- 239000001267 polyvinylpyrrolidone Substances 0.000 description 1
- 229920000036 polyvinylpyrrolidone Polymers 0.000 description 1
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 description 1
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- 238000002360 preparation method Methods 0.000 description 1
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- 229940007042 proteus vulgaris Drugs 0.000 description 1
- 230000005180 public health Effects 0.000 description 1
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- 125000002652 ribonucleotide group Chemical group 0.000 description 1
- 125000000548 ribosyl group Chemical group C1([C@H](O)[C@H](O)[C@H](O1)CO)* 0.000 description 1
- 229960001860 salicylate Drugs 0.000 description 1
- YGSDEFSMJLZEOE-UHFFFAOYSA-M salicylate Chemical compound OC1=CC=CC=C1C([O-])=O YGSDEFSMJLZEOE-UHFFFAOYSA-M 0.000 description 1
- 238000012163 sequencing technique Methods 0.000 description 1
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- 239000011780 sodium chloride Substances 0.000 description 1
- 239000001509 sodium citrate Substances 0.000 description 1
- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 description 1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/18—Testing for antimicrobial activity of a material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
- C07K14/245—Escherichia (G)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06078—Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Communicable Diseases (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Oncology (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US6089897P | 1997-10-03 | 1997-10-03 | |
| US60/060,898 | 1997-10-03 | ||
| PCT/US1998/005671 WO1999017791A1 (en) | 1997-10-03 | 1998-03-20 | Methods and compositions for reducing bacterial tolerance of disinfectants and organic solvents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2305528A1 true CA2305528A1 (en) | 1999-04-15 |
Family
ID=22032436
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002305528A Abandoned CA2305528A1 (en) | 1997-10-03 | 1998-03-20 | Methods and compositions for reducing bacterial tolerance of disinfectants and organic solvents |
Country Status (6)
| Country | Link |
|---|---|
| US (3) | US6068972A (enExample) |
| EP (1) | EP1019076A4 (enExample) |
| JP (1) | JP2001518514A (enExample) |
| AU (1) | AU751014B2 (enExample) |
| CA (1) | CA2305528A1 (enExample) |
| WO (1) | WO1999017791A1 (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1077718B1 (en) * | 1998-05-18 | 2002-08-14 | PHARMACIA & UPJOHN COMPANY | Enhancement of oxazolidinone antibacterial agents activity by arginine derivatives |
| US6346391B1 (en) | 1999-07-22 | 2002-02-12 | Trustees Of Tufts College | Methods of reducing microbial resistance to drugs |
| US20020132798A1 (en) | 2000-06-16 | 2002-09-19 | Nelson Mark L. | 7-phenyl-substituted tetracycline compounds |
| WO2002016940A2 (en) * | 2000-08-23 | 2002-02-28 | Genome Therapeutics Corporation | Genomics-assisted rapid identification of targets |
| US7713472B2 (en) * | 2001-01-12 | 2010-05-11 | Board Of Regents, The University Of Texas System | Antiseptic derivatives with broad spectrum antimicrobial activity for the impregnation of surfaces |
| US7075582B2 (en) | 2001-07-13 | 2006-07-11 | Paratek Pharmaceuticals, Inc. | Methods for identifying and using MarR family polypeptide binding compounds |
| WO2003006626A2 (en) * | 2001-07-13 | 2003-01-23 | Trustees Of Tufts College | CRYSTAL STRUCTURE OF A MarR FAMILY POLYPEPTIDE |
| US20060084678A1 (en) * | 2001-07-13 | 2006-04-20 | Paratek Pharmaceuticals, Inc. | Methods for identifying and using MarR family polypeptide binding compounds |
| US20050255538A1 (en) * | 2002-03-15 | 2005-11-17 | Buxser Stephen E | Methods for screening for AcrAB efflux pump inhibitors |
| WO2004062674A2 (en) * | 2003-01-07 | 2004-07-29 | Paratek Pharmaceuticals, Inc. | Substituted polyamines as inhibitors of bacterial efflux pumps |
| PL1644024T3 (pl) | 2003-06-06 | 2020-03-31 | Board Of Regents, The University Of Texas System | Przeciwdrobnoustrojowe roztwory do płukania |
| US7652040B2 (en) * | 2003-06-19 | 2010-01-26 | Janssen Pharmaceutica N.V. | Aminosulfonyl substituted 4-(aminomethyl)-piperidine benzamides as 5HT4-antagonists |
| JP2007522835A (ja) * | 2004-01-20 | 2007-08-16 | ボード・オブ・リージエンツ，ザ・ユニバーシテイ・オブ・テキサス・システム | 医療装置に消毒組成物をコーティングする、および含浸させる方法 |
| US20070154621A1 (en) | 2005-11-18 | 2007-07-05 | Issam Raad | Methods for coating surfaces with antimicrobial agents |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW318189B (enExample) * | 1991-12-06 | 1997-10-21 | American Cyanamid Co | |
| US5384259A (en) * | 1991-12-06 | 1995-01-24 | American Cyanamid Company | Construct and method for expression of tetracycline resistance genes in E. Coli |
| EP0658213B1 (en) * | 1992-08-28 | 1998-11-18 | Trustees Of Tufts College | Multiple antibiotic resistance operon assays |
| US5989832A (en) * | 1995-04-21 | 1999-11-23 | Microcide Pharmaceuticals, Inc. | Method for screening for non-tetracycline efflux pump inhibitors |
-
1997
- 1997-10-07 US US08/946,225 patent/US6068972A/en not_active Expired - Lifetime
-
1998
- 1998-03-20 JP JP2000514662A patent/JP2001518514A/ja active Pending
- 1998-03-20 EP EP98911949A patent/EP1019076A4/en not_active Withdrawn
- 1998-03-20 WO PCT/US1998/005671 patent/WO1999017791A1/en not_active Ceased
- 1998-03-20 CA CA002305528A patent/CA2305528A1/en not_active Abandoned
- 1998-03-20 AU AU65785/98A patent/AU751014B2/en not_active Ceased
-
2000
- 2000-02-29 US US09/515,705 patent/US6448006B1/en not_active Expired - Fee Related
-
2002
- 2002-07-24 US US10/205,591 patent/US20030171317A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US6448006B1 (en) | 2002-09-10 |
| AU751014B2 (en) | 2002-08-08 |
| EP1019076A4 (en) | 2002-01-23 |
| JP2001518514A (ja) | 2001-10-16 |
| US6068972A (en) | 2000-05-30 |
| WO1999017791A1 (en) | 1999-04-15 |
| US20030171317A1 (en) | 2003-09-11 |
| EP1019076A1 (en) | 2000-07-19 |
| AU6578598A (en) | 1999-04-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| FZDE | Discontinued |