CA2304368A1 - Reactifs et procedes utiles pour detecter des maladies de la prostate, du sein et des ovaires - Google Patents

Reactifs et procedes utiles pour detecter des maladies de la prostate, du sein et des ovaires Download PDF

Info

Publication number
CA2304368A1
CA2304368A1 CA002304368A CA2304368A CA2304368A1 CA 2304368 A1 CA2304368 A1 CA 2304368A1 CA 002304368 A CA002304368 A CA 002304368A CA 2304368 A CA2304368 A CA 2304368A CA 2304368 A1 CA2304368 A1 CA 2304368A1
Authority
CA
Canada
Prior art keywords
sequence
polynucleotide
polypeptide
breast
prostate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002304368A
Other languages
English (en)
Inventor
Patricia A. Billing-Medel
Maurice Cohen
Tracey L. Colpitts
Paula N. Friedman
Julian Gordon
Edward N. Granados
Steven C. Hodges
Michael R. Klass
Jon D. Kratochvil
Barbara T. Merchant
John C. Russell
Stephen D. Stroupe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2304368A1 publication Critical patent/CA2304368A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3015—Breast
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3069—Reproductive system, e.g. ovaria, uterus, testes, prostate
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/136—Screening for pharmacological compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Physics & Mathematics (AREA)
  • Hospice & Palliative Care (AREA)
  • Biotechnology (AREA)
  • Reproductive Health (AREA)
  • Pregnancy & Childbirth (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)

Abstract

L'invention concerne un ensemble de séquences contiguës et se recouvrant partiellement d'ADNc et des polypeptides codés par lesdites séquences, désignées PS214 et transcrites depuis le tissu de la prostate, du sein et de l'ovaire. Ces séquences sont utiles pour effectuer la détection, le diagnostic, la stadification, le contrôle, le pronostic, l'imagerie in vivo, la prévention et le traitement de maladies et de pathologies de la prostate, du sein ou des ovaires, telles que le cancer de la prostate, du sein ou des ovaires, ou pour déterminer la prédisposition d'un individu à ces maladies et à ces pathologies. Elle concerne également des anticorps se fixant de façon spécifique au polypeptide ou à la protéine codés par PS214, ainsi que des agonistes ou des inhibiteurs empêchant l'action du polypeptide de PS214 spécifique pour le tissu, ces molécules étant utiles pour le traitement thérapeutique des maladies, des tumeurs ou des métastases de la prostate, du sein ou des ovaires.
CA002304368A 1997-09-19 1998-09-18 Reactifs et procedes utiles pour detecter des maladies de la prostate, du sein et des ovaires Abandoned CA2304368A1 (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US93838397A 1997-09-19 1997-09-19
US08/938,383 1997-09-19
US99707497A 1997-12-23 1997-12-23
US08/997,074 1997-12-23
PCT/US1998/019496 WO1999014357A2 (fr) 1997-09-19 1998-09-18 Reactifs et procedes utiles pour detecter des maladies de la prostate, du sein et des ovaires

Publications (1)

Publication Number Publication Date
CA2304368A1 true CA2304368A1 (fr) 1999-03-25

Family

ID=27130111

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002304368A Abandoned CA2304368A1 (fr) 1997-09-19 1998-09-18 Reactifs et procedes utiles pour detecter des maladies de la prostate, du sein et des ovaires

Country Status (3)

Country Link
EP (1) EP1015625A2 (fr)
CA (1) CA2304368A1 (fr)
WO (1) WO1999014357A2 (fr)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5861248A (en) * 1996-03-29 1999-01-19 Urocor, Inc. Biomarkers for detection of prostate cancer
US5919638A (en) * 1996-10-08 1999-07-06 Abbott Laboratories Reagents and methods useful for detecting prostate tumors

Also Published As

Publication number Publication date
WO1999014357A9 (fr) 1999-07-08
EP1015625A2 (fr) 2000-07-05
WO1999014357A3 (fr) 1999-05-27
WO1999014357A2 (fr) 1999-03-25

Similar Documents

Publication Publication Date Title
US6465181B2 (en) Reagents and methods useful for detecting diseases of the prostate
US20060154291A1 (en) Reagents and methods useful for detecting diseases of the breast
EP1032706A1 (fr) Reactifs et procedes utiles pour detecter des maladies de la poitrine
WO1999002714A1 (fr) Reactifs et procedes utilises pour detecter les maladies du sein
US6770435B1 (en) Reagents and methods useful for detecting diseases of the breast
EP1003779A1 (fr) Reactifs et methodes utiles pour detecter des pathologies mammaires
US6538119B2 (en) Reagents and methods useful for detecting diseases of the breast
US20060029963A1 (en) Reagents and methods useful for detecting diseases of the breast
US20020018990A1 (en) Reagents and methods useful for detecting diseases of the breast
US20020037503A1 (en) Reagents and methods useful for detecting diseases of the breast
EP1027457A1 (fr) Reactifs et procedes utiles pour detecter des maladies du sein
CA2303404A1 (fr) Reactifs et methodes servant a detecter les maladies de la prostate
US20020045165A1 (en) Reagents and methods useful for detecting diseases of the breast
CA2358748A1 (fr) Reactifs et procedes utiles a la detection des pathologies mammaires
US20020188115A1 (en) Reagents and methods useful for detecting diseases of the breast
CA2304368A1 (fr) Reactifs et procedes utiles pour detecter des maladies de la prostate, du sein et des ovaires
US20040072210A1 (en) Reagents and methods useful for detecting diseases of the breast

Legal Events

Date Code Title Description
FZDE Discontinued