CA2301554A1 - Molecules d'adn codant pour des proteines receptrices nucleaires - Google Patents

Molecules d'adn codant pour des proteines receptrices nucleaires Download PDF

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Publication number
CA2301554A1
CA2301554A1 CA002301554A CA2301554A CA2301554A1 CA 2301554 A1 CA2301554 A1 CA 2301554A1 CA 002301554 A CA002301554 A CA 002301554A CA 2301554 A CA2301554 A CA 2301554A CA 2301554 A1 CA2301554 A1 CA 2301554A1
Authority
CA
Canada
Prior art keywords
human
protein
nnr2
expression vector
host cell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002301554A
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English (en)
Inventor
Fang Chen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2301554A1 publication Critical patent/CA2301554A1/fr
Abandoned legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70567Nuclear receptors, e.g. retinoic acid receptor [RAR], RXR, nuclear orphan receptors

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)

Abstract

L'invention concerne l'isolement et la caractérisation de molécules d'ADNc codant pour deux protéines réceptrices nucléaires humaines, désignées par nNR1, nNR2 et/ou nNR2-1. L'invention concerne également des vecteurs recombinants, des cellules hôtes recombinantes, des techniques de criblage permettant l'identification de modulateurs de l'activité nNR1, nNR2 et/ou nNR2-1, et la production d'antibiotiques contre nNR1, nNR2 et/ou de nNR2-1, ou des épitopes de ces derniers.
CA002301554A 1997-08-27 1998-08-27 Molecules d'adn codant pour des proteines receptrices nucleaires Abandoned CA2301554A1 (fr)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US5709097P 1997-08-27 1997-08-27
US6290297P 1997-10-21 1997-10-21
US7863398P 1998-03-19 1998-03-19
US60/078,633 1998-03-19
US60/062,902 1998-03-19
US60/057,090 1998-03-19
PCT/US1998/017826 WO1999010367A1 (fr) 1997-08-27 1998-08-27 Molecules d'adn codant pour des proteines receptrices nucleaires

Publications (1)

Publication Number Publication Date
CA2301554A1 true CA2301554A1 (fr) 1999-03-04

Family

ID=27369158

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002301554A Abandoned CA2301554A1 (fr) 1997-08-27 1998-08-27 Molecules d'adn codant pour des proteines receptrices nucleaires

Country Status (4)

Country Link
EP (1) EP1007540A4 (fr)
JP (1) JP2001513984A (fr)
CA (1) CA2301554A1 (fr)
WO (1) WO1999010367A1 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0866127A3 (fr) 1997-03-17 1999-12-22 Smithkline Beecham Plc HE8AN36, un homologue de récepteur d'hormone stéroide
WO2000042180A1 (fr) * 1999-01-14 2000-07-20 Kyowa Hakko Kogyo Co., Ltd. Nouvelle proteine
US20060148030A1 (en) * 2002-03-25 2006-07-06 Fujisawa Pharmaceutical Co., Ltd Nuclear receptor err y 3

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5071773A (en) * 1986-10-24 1991-12-10 The Salk Institute For Biological Studies Hormone receptor-related bioassays

Also Published As

Publication number Publication date
WO1999010367A1 (fr) 1999-03-04
JP2001513984A (ja) 2001-09-11
EP1007540A1 (fr) 2000-06-14
EP1007540A4 (fr) 2003-06-18

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued