CA2298828A1 - Passive, non-invasive method to quantify objectively the level and density of a neural blockade - Google Patents

Passive, non-invasive method to quantify objectively the level and density of a neural blockade Download PDF

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Publication number
CA2298828A1
CA2298828A1 CA002298828A CA2298828A CA2298828A1 CA 2298828 A1 CA2298828 A1 CA 2298828A1 CA 002298828 A CA002298828 A CA 002298828A CA 2298828 A CA2298828 A CA 2298828A CA 2298828 A1 CA2298828 A1 CA 2298828A1
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CA
Canada
Prior art keywords
density
level
passive
neural
blockade
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002298828A
Other languages
French (fr)
Other versions
CA2298828C (en
Inventor
Wayne I. Sternberger
Robert S. Greenberg
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Johns Hopkins University
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/918,446 external-priority patent/US6002960A/en
Application filed by Individual filed Critical Individual
Publication of CA2298828A1 publication Critical patent/CA2298828A1/en
Application granted granted Critical
Publication of CA2298828C publication Critical patent/CA2298828C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/103—Detecting, measuring or recording devices for testing the shape, pattern, colour, size or movement of the body or parts thereof, for diagnostic purposes
    • A61B5/11—Measuring movement of the entire body or parts thereof, e.g. head or hand tremor, mobility of a limb
    • A61B5/1104—Measuring movement of the entire body or parts thereof, e.g. head or hand tremor, mobility of a limb induced by stimuli or drugs
    • A61B5/1106—Measuring movement of the entire body or parts thereof, e.g. head or hand tremor, mobility of a limb induced by stimuli or drugs to assess neuromuscular blockade, e.g. to estimate depth of anaesthesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316—Modalities, i.e. specific diagnostic methods
    • A61B5/389—Electromyography [EMG]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/18—Shielding or protection of sensors from environmental influences, e.g. protection from mechanical damage
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/024—Detecting, measuring or recording pulse rate or heart rate
    • A61B5/0245—Detecting, measuring or recording pulse rate or heart rate by using sensing means generating electric signals, i.e. ECG signals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7203—Signal processing specially adapted for physiological signals or for diagnostic purposes for noise prevention, reduction or removal
    • A61B5/7207—Signal processing specially adapted for physiological signals or for diagnostic purposes for noise prevention, reduction or removal of noise induced by motion artifacts
    • A61B5/721—Signal processing specially adapted for physiological signals or for diagnostic purposes for noise prevention, reduction or removal of noise induced by motion artifacts using a separate sensor to detect motion or using motion information derived from signals other than the physiological signal to be measured
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7203—Signal processing specially adapted for physiological signals or for diagnostic purposes for noise prevention, reduction or removal
    • A61B5/7217—Signal processing specially adapted for physiological signals or for diagnostic purposes for noise prevention, reduction or removal of noise originating from a therapeutic or surgical apparatus, e.g. from a pacemaker

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physics & Mathematics (AREA)
  • Public Health (AREA)
  • Pathology (AREA)
  • Anesthesiology (AREA)
  • Neurology (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Physiology (AREA)
  • Dentistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Measuring And Recording Apparatus For Diagnosis (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
  • Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)

Abstract

Electromyogram, temperature and heart rate measurement which correlate to the dermatome level, and density of neural blokade are obtained in a passive manner, i.e., the patient is not stimulated, or exposed to any sensor that requires an active conduction in order to make a measurement. No active patient participation or response is required. The measurements obtained provide objective and quantitative indications of, for example, epidural blockade with local anesthetics thus allowing objective real time assessment of density, and level of neural blockade.
CA002298828A 1997-08-26 1998-08-25 Passive, non-invasive method to quantify objectively the level and density of a neural blockade Expired - Fee Related CA2298828C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/918,446 1997-08-26
US08/918,446 US6002960A (en) 1996-08-27 1997-08-26 Passive, non-invasive method to quantify objectively the level and density of a neural blockade
PCT/US1998/017529 WO1999009885A1 (en) 1997-08-26 1998-08-25 Passive, non-invasive method to quantify objectively the level and density of a neural blockade

Publications (2)

Publication Number Publication Date
CA2298828A1 true CA2298828A1 (en) 1999-03-04
CA2298828C CA2298828C (en) 2003-11-18

Family

ID=25440400

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002298828A Expired - Fee Related CA2298828C (en) 1997-08-26 1998-08-25 Passive, non-invasive method to quantify objectively the level and density of a neural blockade

Country Status (5)

Country Link
EP (1) EP1009279A4 (en)
JP (1) JP2001513386A (en)
AU (1) AU731669B2 (en)
CA (1) CA2298828C (en)
WO (1) WO1999009885A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5221086B2 (en) * 2007-09-07 2013-06-26 フクダ電子株式会社 Biological information monitor and biological information monitor control program
DE102009003897A1 (en) * 2009-01-03 2010-07-15 Andreas Dr. Penno Apparatus and method for monitoring the success of spinal anesthesia
KR101232492B1 (en) * 2011-02-10 2013-02-12 성균관대학교산학협력단 Anaesthsia depth and facial nerve monitoring apparatus using emg signal and method thereof
KR101658680B1 (en) * 2011-02-23 2016-09-21 사회복지법인 삼성생명공익재단 Apparatus and method for monitoring facial nerve
CN113729644A (en) * 2021-09-06 2021-12-03 中山大学 Method for detecting regional nerve block anesthesia effect by using temperature sensing array

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4570640A (en) * 1981-08-06 1986-02-18 Barsa John E Sensory monitoring apparatus and method
US5131401A (en) * 1990-09-10 1992-07-21 Axon Medical Inc. Method and apparatus for monitoring neuromuscular blockage
US5195531A (en) * 1991-03-01 1993-03-23 Bennett Henry L Anesthesia adequacy monitor and method
US5320109A (en) * 1991-10-25 1994-06-14 Aspect Medical Systems, Inc. Cerebral biopotential analysis system and method
US5772591A (en) * 1995-06-06 1998-06-30 Patient Comfort, Inc. Electrode assembly for signaling a monitor

Also Published As

Publication number Publication date
EP1009279A1 (en) 2000-06-21
CA2298828C (en) 2003-11-18
AU9118198A (en) 1999-03-16
JP2001513386A (en) 2001-09-04
EP1009279A4 (en) 2004-05-12
WO1999009885A1 (en) 1999-03-04
AU731669B2 (en) 2001-04-05

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