CA2276087A1 - Transgenic plants with modified sterol biosynthetic pathways - Google Patents

Transgenic plants with modified sterol biosynthetic pathways Download PDF

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Publication number
CA2276087A1
CA2276087A1 CA002276087A CA2276087A CA2276087A1 CA 2276087 A1 CA2276087 A1 CA 2276087A1 CA 002276087 A CA002276087 A CA 002276087A CA 2276087 A CA2276087 A CA 2276087A CA 2276087 A1 CA2276087 A1 CA 2276087A1
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CA
Canada
Prior art keywords
sterol
plant
delta
smt
dna
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002276087A
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English (en)
French (fr)
Inventor
W. David Nes
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2276087A1 publication Critical patent/CA2276087A1/en
Abandoned legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/1003Transferases (2.) transferring one-carbon groups (2.1)
    • C12N9/1007Methyltransferases (general) (2.1.1.)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8261Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
    • C12N15/8271Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
    • C12N15/8279Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8261Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
    • C12N15/8271Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
    • C12N15/8279Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance
    • C12N15/8286Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance for insect resistance
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P33/00Preparation of steroids
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A40/00Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
    • Y02A40/10Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in agriculture
    • Y02A40/146Genetically Modified [GMO] plants, e.g. transgenic plants

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Nutrition Science (AREA)
  • Medicinal Chemistry (AREA)
  • Insects & Arthropods (AREA)
  • Pest Control & Pesticides (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
CA002276087A 1996-12-26 1997-12-24 Transgenic plants with modified sterol biosynthetic pathways Abandoned CA2276087A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US3392396P 1996-12-26 1996-12-26
US60/033,923 1996-12-26
PCT/US1997/023495 WO1998045457A1 (en) 1996-12-26 1997-12-24 Transgenic plants with modified sterol biosynthetic pathways

Publications (1)

Publication Number Publication Date
CA2276087A1 true CA2276087A1 (en) 1998-10-15

Family

ID=21873233

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002276087A Abandoned CA2276087A1 (en) 1996-12-26 1997-12-24 Transgenic plants with modified sterol biosynthetic pathways

Country Status (6)

Country Link
EP (1) EP0958370A1 (pt)
CN (1) CN1247569A (pt)
AU (1) AU724046B2 (pt)
BR (1) BR9714439A (pt)
CA (1) CA2276087A1 (pt)
WO (1) WO1998045457A1 (pt)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000008190A2 (en) * 1998-08-03 2000-02-17 Arizona Board Of Regents On Behalf Of The University Of Arizona Sterol methyltransferase gene
ATE446370T1 (de) 1999-04-12 2009-11-15 Monsanto Technology Llc Öl, das brassicastanol enthält
AU7617600A (en) * 1999-09-30 2001-04-30 E.I. Du Pont De Nemours And Company Genes encoding sterol delta-15 reductase in plants
WO2001031027A1 (en) * 1999-10-27 2001-05-03 Unilever N.V Process for modifying plants
GB9925453D0 (en) * 1999-10-27 1999-12-29 Univ Bristol Increasing isoprenoid biosynthesis
BR0109953A (pt) * 2000-04-14 2003-05-27 Unilever Nv Semente de tabaco, canola, girassol, colza ou soja, uso de um gene que expressa um smt1, método para obter sementes, sementes, método de obtenção de óleo que compreende esteróis, produto alimentìcio, método para aumentar o nìvel de esteróis nas sementes de plantas e/ou diminuir o nìvel de colesterol em sementes de plantas
EP1335985A2 (en) * 2000-11-24 2003-08-20 Unilever N.V. Process for increasing the level of sterols in plants
US6822142B2 (en) 2001-01-05 2004-11-23 Monsanto Company Transgenic plants containing altered levels of steroid compounds
DE10203352A1 (de) * 2002-01-29 2003-07-31 Basf Ag Verfahren zur Herstellung von 7-Dehydrocholesterol und/oder dessen biosynthetischen Zwischen- und/oder Folgeprodukten in transgenen Organismen
EP2216405A1 (en) 2002-05-03 2010-08-11 Monsanto Technology LLC Speed specific USP promoters for expressing genes in plants
BR0312325A (pt) * 2002-07-16 2005-04-12 Unilever Nv Método de aumento do nìvel de 4-desmetil esteróis e método de transformação de planta
CA2598792A1 (en) 2005-03-02 2006-09-08 Metanomics Gmbh Process for the production of fine chemicals
JP5174430B2 (ja) * 2007-11-06 2013-04-03 花王株式会社 2−フェニルエチルアルコールの製造方法
US8927812B2 (en) 2009-12-09 2015-01-06 Basf Plant Science Company Gmbh Methods for increasing the resistance of plants to fungi by silencing the fungal SMT1-gene
AR086406A1 (es) * 2011-05-16 2013-12-11 Basf Plant Science Co Gmbh Plantas transgenicas resistentes a nematodos
ES2842501T5 (es) 2015-09-21 2023-04-13 Modern Meadow Inc Materiales compuestos de tejido reforzados con fibras
WO2017142896A1 (en) 2016-02-15 2017-08-24 Modern Meadow, Inc. Method for making a biofabricated material containing collagen fibrils
CA3008850A1 (en) 2017-06-29 2018-12-29 Modern Meadow, Inc. Yeast strains and methods for producing collagen
AU2018253595A1 (en) 2017-11-13 2019-05-30 Modern Meadow, Inc. Biofabricated leather articles having zonal properties
CA3121853A1 (en) 2019-01-17 2020-07-23 Modern Meadow, Inc. Layered collagen materials and methods of making the same
CN111500624B (zh) * 2020-06-30 2020-10-30 中国农业科学院生物技术研究所 CrSMT基因在提高植物对于生物胁迫以及非生物胁迫抗性中的用途

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5306862A (en) * 1990-10-12 1994-04-26 Amoco Corporation Method and composition for increasing sterol accumulation in higher plants
CA2258571A1 (en) * 1996-06-21 1997-12-24 The General Hospital Corporation Plant sterol reductases and uses thereof

Also Published As

Publication number Publication date
CN1247569A (zh) 2000-03-15
AU5709998A (en) 1998-10-30
EP0958370A1 (en) 1999-11-24
WO1998045457A1 (en) 1998-10-15
AU724046B2 (en) 2000-09-07
BR9714439A (pt) 2000-03-21

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Legal Events

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FZDE Discontinued
FZDE Discontinued

Effective date: 20031224