CA2273192A1 - Therapie de l'infection a virus de l'immunodeficience humaine (vih) par inactivation de co-recepteurs du vih - Google Patents

Therapie de l'infection a virus de l'immunodeficience humaine (vih) par inactivation de co-recepteurs du vih Download PDF

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Publication number
CA2273192A1
CA2273192A1 CA002273192A CA2273192A CA2273192A1 CA 2273192 A1 CA2273192 A1 CA 2273192A1 CA 002273192 A CA002273192 A CA 002273192A CA 2273192 A CA2273192 A CA 2273192A CA 2273192 A1 CA2273192 A1 CA 2273192A1
Authority
CA
Canada
Prior art keywords
chemokine
receptor
hiv
expression
cell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002273192A
Other languages
English (en)
Inventor
Si-Yi Chen
An-Gang Yang
Xuefan Bai
Ji-Dai Chen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wake Forest University
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2273192A1 publication Critical patent/CA2273192A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/521—Chemokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Abstract

Cette invention a trait à des compositions ainsi qu'aux méthodes afférentes visant au traitement et/ou à la prévention de l'infection à virus de l'immunodéficience humaine (VIH). On fait notamment appel, dans le cadre de cette invention, à de nouvelles compositions afin d'empêcher l'expression cellulaire en surface d'un co-récepteur nécessaire à la fixation du virus VIH à ses cellules cibles et l'on applique, pour ce faire, les méthodes afférentes.
CA002273192A 1996-12-02 1997-12-02 Therapie de l'infection a virus de l'immunodeficience humaine (vih) par inactivation de co-recepteurs du vih Abandoned CA2273192A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US3227796P 1996-12-02 1996-12-02
US60/032,277 1996-12-02
PCT/US1997/022198 WO1998024923A1 (fr) 1996-12-02 1997-12-02 Therapie de l'infection a virus de l'immunodeficience humaine (vih) par inactivation de co-recepteurs du vih

Publications (1)

Publication Number Publication Date
CA2273192A1 true CA2273192A1 (fr) 1998-06-11

Family

ID=21864069

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002273192A Abandoned CA2273192A1 (fr) 1996-12-02 1997-12-02 Therapie de l'infection a virus de l'immunodeficience humaine (vih) par inactivation de co-recepteurs du vih

Country Status (6)

Country Link
EP (1) EP0963441A4 (fr)
JP (1) JP2001505055A (fr)
AU (1) AU721121B2 (fr)
CA (1) CA2273192A1 (fr)
IL (2) IL130160A0 (fr)
WO (1) WO1998024923A1 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001042308A2 (fr) * 1999-12-08 2001-06-14 Novartis Ag Methodes et compositions utiles pour l'inhibition de l'infection, dependante de ccr5, de cellules par vhi-1
USRE47770E1 (en) 2002-07-18 2019-12-17 Merus N.V. Recombinant production of mixtures of antibodies
ES2368733T3 (es) 2002-07-18 2011-11-21 Merus B.V. Producción recombinante de mezclas de anticuerpos.
CA2527694C (fr) 2003-05-30 2015-07-14 Hendricus Renerus Jacobus Mattheus Hoogenboom Banque de fab pour la preparation de fab anti-vegf et antirabique
US20100069614A1 (en) 2008-06-27 2010-03-18 Merus B.V. Antibody producing non-human mammals
MX360109B (es) 2012-04-20 2018-10-23 Merus Nv Metodos y medios para la produccion de moleculas de tipo ig.

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69521331T2 (de) * 1994-11-01 2001-09-20 Winfried Wels Nukleinsäure-einbringungssystem
CA2271291A1 (fr) * 1996-11-06 1998-05-14 The Government Of The United States Of America, Represented By The Secre Tary, Department Of Health And Human Services Proproteines similaires a l'exotoxine de pseudomonas, pouvant etre activees par une protease
US6100387A (en) * 1997-02-28 2000-08-08 Genetics Institute, Inc. Chimeric polypeptides containing chemokine domains
US6214540B1 (en) * 1997-03-26 2001-04-10 University Of Maryland Biotechnology Institute Chemokines that inhibit immunodeficiency virus infection and methods based thereon
GB9718609D0 (en) * 1997-09-02 1997-11-05 Imp College Innovations Ltd Fusion protein
MXPA00003885A (es) * 1997-10-22 2004-04-23 Inst Genetics Llc Quimiocinas con modificiaciones de la terminacion amino.
US6110695A (en) * 1997-12-02 2000-08-29 The Regents Of The University Of California Modulating the interaction of the chemokine, B Lymphocyte Hemoattractant, and its Receptor, BLR1

Also Published As

Publication number Publication date
AU721121B2 (en) 2000-06-22
IL130160A0 (en) 2000-06-01
WO1998024923A1 (fr) 1998-06-11
AU5372498A (en) 1998-06-29
EP0963441A1 (fr) 1999-12-15
IL130160A (en) 2007-07-04
EP0963441A4 (fr) 2002-10-02
JP2001505055A (ja) 2001-04-17

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued