CA2271582A1 - Procede d'administration d'agents therapeutiques, incluant l'anti-sens avec dosage repetitif - Google Patents

Procede d'administration d'agents therapeutiques, incluant l'anti-sens avec dosage repetitif Download PDF

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Publication number
CA2271582A1
CA2271582A1 CA 2271582 CA2271582A CA2271582A1 CA 2271582 A1 CA2271582 A1 CA 2271582A1 CA 2271582 CA2271582 CA 2271582 CA 2271582 A CA2271582 A CA 2271582A CA 2271582 A1 CA2271582 A1 CA 2271582A1
Authority
CA
Canada
Prior art keywords
lipid
antisense
nucleic acid
peg
particle
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA 2271582
Other languages
English (en)
Inventor
Sean C. Semple
Sandra K. Klimuk
Troy Harasym
Michael J. Hope
Steven M. Ansell
Pieter R. Cullis
Peter Scherrer
Wilson W. K. Mok
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of British Columbia
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2271582A1 publication Critical patent/CA2271582A1/fr
Abandoned legal-status Critical Current

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
CA 2271582 1998-05-14 1999-05-13 Procede d'administration d'agents therapeutiques, incluant l'anti-sens avec dosage repetitif Abandoned CA2271582A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US7895598A 1998-05-14 1998-05-14
US09/078,955 1998-05-14

Publications (1)

Publication Number Publication Date
CA2271582A1 true CA2271582A1 (fr) 1999-11-14

Family

ID=29709302

Family Applications (1)

Application Number Title Priority Date Filing Date
CA 2271582 Abandoned CA2271582A1 (fr) 1998-05-14 1999-05-13 Procede d'administration d'agents therapeutiques, incluant l'anti-sens avec dosage repetitif

Country Status (1)

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CA (1) CA2271582A1 (fr)

Cited By (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001080900A2 (fr) * 2000-04-20 2001-11-01 The University Of British Columbia Procedes permettant d'ameliorer la transfection a mediation splp (particule plasmide-lipide stabilisee) au moyen de destabilisateurs de la membrane endosomale
WO2005026372A1 (fr) * 2003-09-15 2005-03-24 Protiva Biotherapeutics, Inc. Composes conjugues lipidiques polyethyleneglycol-dialkyloxypropyle et utilisations de ces composes
US7189705B2 (en) 2000-04-20 2007-03-13 The University Of British Columbia Methods of enhancing SPLP-mediated transfection using endosomal membrane destabilizers
WO2009153888A1 (fr) 2008-06-19 2009-12-23 日本新薬株式会社 Vecteur de médicament
US7982027B2 (en) 2003-07-16 2011-07-19 Protiva Biotherapeutics, Inc. Lipid encapsulated interfering RNA
US8492359B2 (en) 2008-04-15 2013-07-23 Protiva Biotherapeutics, Inc. Lipid formulations for nucleic acid delivery
US8569256B2 (en) 2009-07-01 2013-10-29 Protiva Biotherapeutics, Inc. Cationic lipids and methods for the delivery of therapeutic agents
US9006417B2 (en) 2010-06-30 2015-04-14 Protiva Biotherapeutics, Inc. Non-liposomal systems for nucleic acid delivery
US9018187B2 (en) 2009-07-01 2015-04-28 Protiva Biotherapeutics, Inc. Cationic lipids and methods for the delivery of therapeutic agents
US9181545B2 (en) 2004-06-07 2015-11-10 Protiva Biotherapeutics, Inc. Lipid encapsulating interfering RNA
US9492386B2 (en) 2002-06-28 2016-11-15 Protiva Biotherapeutics, Inc. Liposomal apparatus and manufacturing methods
US9878042B2 (en) 2009-07-01 2018-01-30 Protiva Biotherapeutics, Inc. Lipid formulations for delivery of therapeutic agents to solid tumors
CN112285247A (zh) * 2020-12-30 2021-01-29 南京广祺医药科技有限公司 一种定量测定血浆中PEGylated-IL-2(1A)的方法及应用
CN114209829A (zh) * 2021-12-17 2022-03-22 中国科学技术大学 负载荧光染料的光热脂质体及其制备方法和用途
CN114740110A (zh) * 2022-03-31 2022-07-12 天津键凯科技有限公司 一种二硬脂酰磷脂酰胆碱纯度的检测方法
US11591544B2 (en) 2020-11-25 2023-02-28 Akagera Medicines, Inc. Ionizable cationic lipids

Cited By (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7189705B2 (en) 2000-04-20 2007-03-13 The University Of British Columbia Methods of enhancing SPLP-mediated transfection using endosomal membrane destabilizers
WO2001080900A3 (fr) * 2000-04-20 2003-04-24 Univ British Columbia Procedes permettant d'ameliorer la transfection a mediation splp (particule plasmide-lipide stabilisee) au moyen de destabilisateurs de la membrane endosomale
WO2001080900A2 (fr) * 2000-04-20 2001-11-01 The University Of British Columbia Procedes permettant d'ameliorer la transfection a mediation splp (particule plasmide-lipide stabilisee) au moyen de destabilisateurs de la membrane endosomale
US11298320B2 (en) 2002-06-28 2022-04-12 Arbutus Biopharma Corporation Liposomal apparatus and manufacturing methods
US9492386B2 (en) 2002-06-28 2016-11-15 Protiva Biotherapeutics, Inc. Liposomal apparatus and manufacturing methods
US9504651B2 (en) 2002-06-28 2016-11-29 Protiva Biotherapeutics, Inc. Lipid compositions for nucleic acid delivery
US11318098B2 (en) 2002-06-28 2022-05-03 Arbutus Biopharma Corporation Liposomal apparatus and manufacturing methods
US7982027B2 (en) 2003-07-16 2011-07-19 Protiva Biotherapeutics, Inc. Lipid encapsulated interfering RNA
US7803397B2 (en) 2003-09-15 2010-09-28 Protiva Biotherapeutics, Inc. Polyethyleneglycol-modified lipid compounds and uses thereof
WO2005026372A1 (fr) * 2003-09-15 2005-03-24 Protiva Biotherapeutics, Inc. Composes conjugues lipidiques polyethyleneglycol-dialkyloxypropyle et utilisations de ces composes
US8936942B2 (en) 2003-09-15 2015-01-20 Protiva Biotherapeutics, Inc. Polyethyleneglycol-modified lipid compounds and uses thereof
US9181545B2 (en) 2004-06-07 2015-11-10 Protiva Biotherapeutics, Inc. Lipid encapsulating interfering RNA
US9926560B2 (en) 2004-06-07 2018-03-27 Protiva Biotherapeutics, Inc. Lipid encapsulating interfering RNA
US11141378B2 (en) 2008-04-15 2021-10-12 Arbutus Biopharma Corporation Lipid formulations for nucleic acid delivery
US8492359B2 (en) 2008-04-15 2013-07-23 Protiva Biotherapeutics, Inc. Lipid formulations for nucleic acid delivery
US9364435B2 (en) 2008-04-15 2016-06-14 Protiva Biotherapeutics, Inc. Lipid formulations for nucleic acid delivery
US8822668B2 (en) 2008-04-15 2014-09-02 Protiva Biotherapeutics, Inc. Lipid formulations for nucleic acid delivery
WO2009153888A1 (fr) 2008-06-19 2009-12-23 日本新薬株式会社 Vecteur de médicament
US11446383B2 (en) 2009-07-01 2022-09-20 Arbutus Biopharma Corporation Lipid formulations for delivery of therapeutic agents
US9878042B2 (en) 2009-07-01 2018-01-30 Protiva Biotherapeutics, Inc. Lipid formulations for delivery of therapeutic agents to solid tumors
US8569256B2 (en) 2009-07-01 2013-10-29 Protiva Biotherapeutics, Inc. Cationic lipids and methods for the delivery of therapeutic agents
US9018187B2 (en) 2009-07-01 2015-04-28 Protiva Biotherapeutics, Inc. Cationic lipids and methods for the delivery of therapeutic agents
US11786598B2 (en) 2009-07-01 2023-10-17 Arbutus Biopharma Corporation Lipid formulations for delivery of therapeutic agents
US9404127B2 (en) 2010-06-30 2016-08-02 Protiva Biotherapeutics, Inc. Non-liposomal systems for nucleic acid delivery
US11718852B2 (en) 2010-06-30 2023-08-08 Arbutus Biopharma Corporation Non-liposomal systems for nucleic acid delivery
US9006417B2 (en) 2010-06-30 2015-04-14 Protiva Biotherapeutics, Inc. Non-liposomal systems for nucleic acid delivery
US9518272B2 (en) 2010-06-30 2016-12-13 Protiva Biotherapeutics, Inc. Non-liposomal systems for nucleic acid delivery
US11591544B2 (en) 2020-11-25 2023-02-28 Akagera Medicines, Inc. Ionizable cationic lipids
CN112285247A (zh) * 2020-12-30 2021-01-29 南京广祺医药科技有限公司 一种定量测定血浆中PEGylated-IL-2(1A)的方法及应用
CN114209829A (zh) * 2021-12-17 2022-03-22 中国科学技术大学 负载荧光染料的光热脂质体及其制备方法和用途
CN114209829B (zh) * 2021-12-17 2023-03-17 中国科学技术大学 负载荧光染料的光热脂质体及其制备方法和用途
CN114740110A (zh) * 2022-03-31 2022-07-12 天津键凯科技有限公司 一种二硬脂酰磷脂酰胆碱纯度的检测方法
CN114740110B (zh) * 2022-03-31 2023-10-24 天津键凯科技有限公司 一种二硬脂酰磷脂酰胆碱纯度的检测方法

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