CA2259496A1 - Preparation of (7s,trans)-2-(2-pyrimidinyl)-7-(hydroxymethyl)octahydro-2h-pyrido[1,2-a]pyrazine - Google Patents
Preparation of (7s,trans)-2-(2-pyrimidinyl)-7-(hydroxymethyl)octahydro-2h-pyrido[1,2-a]pyrazine Download PDFInfo
- Publication number
- CA2259496A1 CA2259496A1 CA002259496A CA2259496A CA2259496A1 CA 2259496 A1 CA2259496 A1 CA 2259496A1 CA 002259496 A CA002259496 A CA 002259496A CA 2259496 A CA2259496 A CA 2259496A CA 2259496 A1 CA2259496 A1 CA 2259496A1
- Authority
- CA
- Canada
- Prior art keywords
- salt
- solution
- tartaric acid
- enantiomer
- formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US2051196P | 1996-07-01 | 1996-07-01 | |
| US60/020,511 | 1996-07-01 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2259496A1 true CA2259496A1 (en) | 1998-01-08 |
Family
ID=21799016
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002259496A Abandoned CA2259496A1 (en) | 1996-07-01 | 1997-06-16 | Preparation of (7s,trans)-2-(2-pyrimidinyl)-7-(hydroxymethyl)octahydro-2h-pyrido[1,2-a]pyrazine |
Country Status (16)
| Country | Link |
|---|---|
| EP (1) | EP0912569A1 (tr) |
| JP (1) | JPH11512751A (tr) |
| KR (1) | KR20000022490A (tr) |
| CN (1) | CN1221418A (tr) |
| AR (1) | AR008251A1 (tr) |
| AU (1) | AU2974497A (tr) |
| BR (1) | BR9710018A (tr) |
| CA (1) | CA2259496A1 (tr) |
| CZ (1) | CZ434998A3 (tr) |
| ID (1) | ID19779A (tr) |
| IL (1) | IL127037A0 (tr) |
| PL (1) | PL330962A1 (tr) |
| TR (1) | TR199802743T2 (tr) |
| WO (1) | WO1998000425A1 (tr) |
| YU (1) | YU61098A (tr) |
| ZA (1) | ZA975806B (tr) |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1990008148A1 (en) * | 1989-01-23 | 1990-07-26 | Pfizer Inc. | Bis-aza-bicyclic anxiolytic agents |
| DE69108743T2 (de) * | 1991-01-31 | 1995-08-17 | Pfizer | Recematspaltung von trans-2-(2-pyrimidinyl)-7-(hydroxymethyl)octahydro-2h-pyrido[1,2-a]-pyrazin. |
-
1997
- 1997-06-16 BR BR9710018A patent/BR9710018A/pt unknown
- 1997-06-16 EP EP97924195A patent/EP0912569A1/en not_active Withdrawn
- 1997-06-16 JP JP9536562A patent/JPH11512751A/ja active Pending
- 1997-06-16 WO PCT/IB1997/000704 patent/WO1998000425A1/en not_active Application Discontinuation
- 1997-06-16 AU AU29744/97A patent/AU2974497A/en not_active Abandoned
- 1997-06-16 TR TR1998/02743T patent/TR199802743T2/tr unknown
- 1997-06-16 CN CN97195398A patent/CN1221418A/zh active Pending
- 1997-06-16 IL IL12703797A patent/IL127037A0/xx unknown
- 1997-06-16 PL PL97330962A patent/PL330962A1/xx unknown
- 1997-06-16 KR KR1019980710931A patent/KR20000022490A/ko not_active Application Discontinuation
- 1997-06-16 CA CA002259496A patent/CA2259496A1/en not_active Abandoned
- 1997-06-16 CZ CZ984349A patent/CZ434998A3/cs unknown
- 1997-06-27 AR ARP970102855A patent/AR008251A1/es unknown
- 1997-06-30 ZA ZA975806A patent/ZA975806B/xx unknown
- 1997-06-30 ID IDP972265A patent/ID19779A/id unknown
-
1998
- 1998-12-29 YU YU61098A patent/YU61098A/sh unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PL330962A1 (en) | 1999-06-21 |
| CZ434998A3 (cs) | 1999-11-17 |
| IL127037A0 (en) | 1999-09-22 |
| WO1998000425A1 (en) | 1998-01-08 |
| BR9710018A (pt) | 1999-08-10 |
| TR199802743T2 (tr) | 1999-03-22 |
| ZA975806B (en) | 1998-12-30 |
| ID19779A (id) | 1998-07-30 |
| KR20000022490A (ko) | 2000-04-25 |
| AU2974497A (en) | 1998-01-21 |
| JPH11512751A (ja) | 1999-11-02 |
| EP0912569A1 (en) | 1999-05-06 |
| CN1221418A (zh) | 1999-06-30 |
| YU61098A (sh) | 1999-09-27 |
| AR008251A1 (es) | 1999-12-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| FZDE | Discontinued |