CA2259145A1 - Hamster ef-1.alpha. transcriptional regulatory dna - Google Patents
Hamster ef-1.alpha. transcriptional regulatory dnaInfo
- Publication number
- CA2259145A1 CA2259145A1 CA002259145A CA2259145A CA2259145A1 CA 2259145 A1 CA2259145 A1 CA 2259145A1 CA 002259145 A CA002259145 A CA 002259145A CA 2259145 A CA2259145 A CA 2259145A CA 2259145 A1 CA2259145 A1 CA 2259145A1
- Authority
- CA
- Canada
- Prior art keywords
- regulatory dna
- hamster
- alpha
- transcriptional regulatory
- expression constructs
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 230000001105 regulatory effect Effects 0.000 title abstract 6
- 241000699800 Cricetinae Species 0.000 title abstract 2
- 230000002103 transcriptional effect Effects 0.000 title 1
- 108020004414 DNA Proteins 0.000 abstract 4
- 108090000623 proteins and genes Proteins 0.000 abstract 3
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 238000013518 transcription Methods 0.000 abstract 1
- 230000035897 transcription Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/67—General methods for enhancing the expression
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
Landscapes
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
The present invention relates to regulatory DNA sequences derived from the hamster EF-1.alpha. gene. The invention further encompasses expression constructs comprising regulatory DNA of the invention, host cells transformed or transfected with the regulatory DNA and methods of increasing gene transcription utilizing the regulatory DNA.
Expression constructs comprising regulatory DNA of the invention operably linked to specific gene sequences are also comprehended.
Expression constructs comprising regulatory DNA of the invention operably linked to specific gene sequences are also comprehended.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/847,218 US5888809A (en) | 1997-05-01 | 1997-05-01 | Hamster EF-1α transcriptional regulatory DNA |
US08/847,218 | 1997-05-01 | ||
PCT/US1998/008906 WO1998049289A1 (en) | 1997-05-01 | 1998-05-01 | HAMSTER EF-1α TRANSCRIPTIONAL REGULATORY DNA |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2259145A1 true CA2259145A1 (en) | 1998-11-05 |
CA2259145C CA2259145C (en) | 2007-08-21 |
Family
ID=38434644
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002259145A Expired - Lifetime CA2259145C (en) | 1997-05-01 | 1998-05-01 | Hamster ef-1.alpha. transcriptional regulatory dna |
Country Status (1)
Country | Link |
---|---|
CA (1) | CA2259145C (en) |
-
1998
- 1998-05-01 CA CA002259145A patent/CA2259145C/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
CA2259145C (en) | 2007-08-21 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
MKEX | Expiry |
Effective date: 20180501 |