CA2259031C - Composes modulateurs de recepteurs d'androgenes, leurs procedes de fabrication et d'utilisation - Google Patents

Composes modulateurs de recepteurs d'androgenes, leurs procedes de fabrication et d'utilisation Download PDF

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Publication number
CA2259031C
CA2259031C CA002259031A CA2259031A CA2259031C CA 2259031 C CA2259031 C CA 2259031C CA 002259031 A CA002259031 A CA 002259031A CA 2259031 A CA2259031 A CA 2259031A CA 2259031 C CA2259031 C CA 2259031C
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CA
Canada
Prior art keywords
nitrogen
carbon
hydrogen
group
heteroatoms selected
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA002259031A
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English (en)
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CA2259031A1 (fr
Inventor
James P. Edwards
Robert Higuchi
Todd Jones
Lawrence G. Hamann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ligand Pharmaceuticals Inc
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Ligand Pharmaceuticals Inc
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Filing date
Publication date
Application filed by Ligand Pharmaceuticals Inc filed Critical Ligand Pharmaceuticals Inc
Priority claimed from PCT/US1997/011222 external-priority patent/WO1997049709A1/fr
Publication of CA2259031A1 publication Critical patent/CA2259031A1/fr
Application granted granted Critical
Publication of CA2259031C publication Critical patent/CA2259031C/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

La présente invention a pour objet des composés non stéroïdiens qui constituent des modulateurs à affinité et à sélectivité élevées pour les récepteurs d'androgènes. Elle a également pour objet des compositions pharmaceutiques contenant ces composés, des procédés d'utilisation de ces composés et de ces compositions pour le traitement de patients nécessitant un agoniste de récepteurs d'androgènes, un agoniste partiel ou une thérapie antagoniste, des intermédiaires utiles dans la préparation des composés, ainsi que des procédés de préparation des composés modulateurs de récepteurs d'androgènes.
CA002259031A 1996-06-27 1997-06-26 Composes modulateurs de recepteurs d'androgenes, leurs procedes de fabrication et d'utilisation Expired - Fee Related CA2259031C (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US2199796P 1996-06-27 1996-06-27
US60/021,997 1996-06-27
PCT/US1997/011222 WO1997049709A1 (fr) 1996-06-27 1997-06-26 Composes modulateurs de recepteurs d'androgenes, leurs procedes de fabrication et d'utilisation

Publications (2)

Publication Number Publication Date
CA2259031A1 CA2259031A1 (fr) 1997-12-31
CA2259031C true CA2259031C (fr) 2006-10-24

Family

ID=37388423

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002259031A Expired - Fee Related CA2259031C (fr) 1996-06-27 1997-06-26 Composes modulateurs de recepteurs d'androgenes, leurs procedes de fabrication et d'utilisation

Country Status (1)

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CA (1) CA2259031C (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7026484B2 (en) 2001-02-23 2006-04-11 Ligand Pharmaceuticals Incorporated Tricyclic androgen receptor modulator compounds and methods

Also Published As

Publication number Publication date
CA2259031A1 (fr) 1997-12-31

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