CA2257234A1 - Compounds active at a novel site on receptor-operated calcium channels useful for treatment of neurological disorders and diseases - Google Patents
Compounds active at a novel site on receptor-operated calcium channels useful for treatment of neurological disorders and diseasesInfo
- Publication number
- CA2257234A1 CA2257234A1 CA002257234A CA2257234A CA2257234A1 CA 2257234 A1 CA2257234 A1 CA 2257234A1 CA 002257234 A CA002257234 A CA 002257234A CA 2257234 A CA2257234 A CA 2257234A CA 2257234 A1 CA2257234 A1 CA 2257234A1
- Authority
- CA
- Canada
- Prior art keywords
- disease
- diseases
- receptor
- treatment
- neurological disorders
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 208000012902 Nervous system disease Diseases 0.000 title abstract 4
- 208000025966 Neurological disease Diseases 0.000 title abstract 3
- 108090000312 Calcium Channels Proteins 0.000 title 1
- 102000003922 Calcium Channels Human genes 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
- 206010021143 Hypoxia Diseases 0.000 abstract 2
- 206010002026 amyotrophic lateral sclerosis Diseases 0.000 abstract 2
- 230000007954 hypoxia Effects 0.000 abstract 2
- 208000028867 ischemia Diseases 0.000 abstract 2
- 208000024827 Alzheimer disease Diseases 0.000 abstract 1
- 208000019901 Anxiety disease Diseases 0.000 abstract 1
- 206010019196 Head injury Diseases 0.000 abstract 1
- 208000023105 Huntington disease Diseases 0.000 abstract 1
- 208000018737 Parkinson disease Diseases 0.000 abstract 1
- 208000036982 Spinal cord ischaemia Diseases 0.000 abstract 1
- 208000006011 Stroke Diseases 0.000 abstract 1
- 230000036506 anxiety Effects 0.000 abstract 1
- 238000007675 cardiac surgery Methods 0.000 abstract 1
- 230000002612 cardiopulmonary effect Effects 0.000 abstract 1
- 230000005779 cell damage Effects 0.000 abstract 1
- 208000037887 cell injury Diseases 0.000 abstract 1
- 230000007278 cognition impairment Effects 0.000 abstract 1
- 206010015037 epilepsy Diseases 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000004770 neurodegeneration Effects 0.000 abstract 1
- 208000015122 neurodegenerative disease Diseases 0.000 abstract 1
- 210000002569 neuron Anatomy 0.000 abstract 1
- 208000020431 spinal cord injury Diseases 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Method and compositions for treating a patient having a neurological disease or disorder, such as stroke, head trauma, spinal cord injury, spinal cord ischemia, ischemia- or hypoxia-induced nerve cell damage, epilepsy, anxiety, neuropsychiatric or cognitive deficits due to ischemia or hypoxia such as those that frequently occur as a consequence of cardiac surgery under cardiopulmonary bypass, or neurodegenerative diseases such as Alzheimer's Disease, Huntington's Disease, Parkinson's Disease, or amyotrophic lateral sclerosis (ALS).
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA002560002A CA2560002A1 (en) | 1996-06-07 | 1996-12-11 | Compounds active at a novel site on receptor-operated calcium channels useful for treatment of neurological disorders and diseases |
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US66301396A | 1996-06-07 | 1996-06-07 | |
US08/663,013 | 1996-06-07 | ||
WOPCT/US96/19525 | 1996-12-06 | ||
US9619525 | 1996-12-06 | ||
PCT/US1996/020697 WO1997046511A1 (en) | 1996-06-07 | 1996-12-11 | Coumpounds active at a novel site on receptor-operated calcium channels useful for treatment of neurological disorders and diseases |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002560002A Division CA2560002A1 (en) | 1996-06-07 | 1996-12-11 | Compounds active at a novel site on receptor-operated calcium channels useful for treatment of neurological disorders and diseases |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2257234A1 true CA2257234A1 (en) | 1997-12-11 |
CA2257234C CA2257234C (en) | 2007-01-16 |
Family
ID=26791398
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002257234A Expired - Fee Related CA2257234C (en) | 1996-06-07 | 1996-12-11 | Compounds active at a novel site on receptor-operated calcium channels useful for treatment of neurological disorders and diseases |
Country Status (1)
Country | Link |
---|---|
CA (1) | CA2257234C (en) |
-
1996
- 1996-12-11 CA CA002257234A patent/CA2257234C/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
CA2257234C (en) | 2007-01-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
MKLA | Lapsed |