CA2256650C - Dosing device for mixing in a continuous process a flowing primary liquid with one or more added secondary liquids - Google Patents
Dosing device for mixing in a continuous process a flowing primary liquid with one or more added secondary liquids Download PDFInfo
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- CA2256650C CA2256650C CA002256650A CA2256650A CA2256650C CA 2256650 C CA2256650 C CA 2256650C CA 002256650 A CA002256650 A CA 002256650A CA 2256650 A CA2256650 A CA 2256650A CA 2256650 C CA2256650 C CA 2256650C
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- liquid
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Abstract
The present invention relates to a dosing device or mixing device for mixing in a continuous process a flowing primary liquid with one or more added secondary liquids of a smaller quantity for obtaining a flowing liquid mixture at a permanent uniform mixing ratio of the mixed liquids.
Description
DOSING DEVICE FOR MIXING IN A CONTINUOUS PROCESS A
FLOWING PRIMARY LIQUID WITH ONE OR MORE ADDED
SECONDARY LIQUIDS
The present invention relates to a dosing device or mixing device for mixing, in a continuous process, a flowing primary liquid with one or more added secondary liquids for obtaining a flowing liquid mixture at a per-manent, uniform mixing ratio of the mixed liquids. Espe-cially the processing industry and medicinal technology require access to dosing devices, by means of which two or more components in liquid state are continuously mix-ed with each other under conditions which yield uniform mixing ratios, i.e. uniform amounts of the components included, in a continuous mixing process. The device and the method according to the invention are especially applicable in the cases where one or some components, so-called secondary components, are to be admixed to a flow-ing primary component and where the amount of secondary components in terms of volume is comparatively small or very small compared with the amount of the primary compo-nent in the finished mixture. In some cases, it is thus desirable to add enzymes, colourants, flavouring agents, vitamins etc. In a flowing quantity of liquid, the con-tent of the added substances, the so-called secondary components, can be as low as 0.05-l0 of the flowing pri-mary component. It is possible by using the inventive method to obtain, with a uniform and continuous mixing ratio, a flow of liquid which can proceed to be packed with an equal content of additives in all packings. An ' example of such a process is, for instance, the prepara-tion of lactose-free sterile milk, where the untreated sterilised and lactose-containing milk is continuously mixed with a quantity of sterile-filtered lactase before packing, the proportions of lactose-containing milk/lac-tase being in the order of 5-10,000, about the same mix-ing ratio being required in all packings that are conti-nuously prepared. In some other cases, higher contents of secondary liquid are required as addition, for instance when colouring or flavouring foodstuffs.
Dosing equipment for mixing flows of liquid having different flow ratios is known, but such equipment has essentially been directed to obtaining a constant mixing ratio by letting the combined flows of liquid being join-ed and conducted in a loop, i.e. a certain part of the flow of liquid is deflected from the main conduit and recirculated to a point in the flow conduit which is positioned downstream. The mixed liquid or parts thereof will in this manner circulate several times through the loop to obtain a good mixing when the loop has finally been passed. The present invention, which operates with-out a mixing loop, is considerably simpler in its techni-cal design and permits great flexibility as regards the amount and type of additives and is, above all, easier to adjust between the use of different mixing components.
The dosing device according to the invention preferably is adapted to be used in the foodstuff industry but may also be used in medicinal industry for continuous mixing of components in liquid state.
An embodiment of the invention will be described below with reference to the accompanying schematic drawing, in which Fig. 1 illustrates the dosing device, Fig. 2 illustrates a special device with a plurality of needle-like nozzles for supplying a secondary liquid and Fig. 3 shows a flexible plastic bag for storing steri-lised secondary liquid. As mentioned above, the described device comprises a means for mixing, with great accuracy to volume, a first liquid, here called primary liquid, with the second liquid, here called secondary liquid, the mixing ratio being such that there is a very great difference between the individual volumes of the mixed liquids. As pointed out above, in many medicinal pro-cesses but also in connection with other processes, for instance, colouring of a liquid or adding of e.g. enzymes or flavouring agents to a liquid, there is a need of add-ing a smaller amount of secondary liquid to an essential-ly larger amount of primary liquid. In a continuous mix-ing process, it is most important that the mixing ratio, in spite of the differences in volume between the mixed liquids, is constant and controllable all the time during the process, such that, for instance, the flavour or the enzyme content of the resulting mixed liquid will not vary.
The apparatus shown in Fig. 1 consists of a flow pipe 26 for primary liquid, the amount of passing primary liquid being controllable by means of a flow meter 22, which registers the amount of passing primary liquid and which by means of the regulator 20 controls the speed of the peristaltic pump 21. In the case shown, the secondary liquid is taken from a plastic bag 19 containing, in this case, sterilised secondary liquid 28. The secondary liquid 28 is passed via the conduit 27 to a peristaltic pump 21 controlled by the regulator 20 and being of known type, comprising a rotatable cylindrical body 29, which at its circumference supports rollers 30, which in the case shown are positioned diametrically opposite each other in the cylindrical body 29, and which with its rollers projects outside the periphery of the rotatable body 29. At least part 27' of the conduit 27 is made of a flexible material, e.g. rubber or plastic, and this part 27' of the conduit 27 is arranged in a duct 31 of the pump 21.
During rotation of the cylindrical body 29, the flexible conduit 27' is compressed by the rollers 30, the liquid contained in the conduit 27' between the rollers 30 being pressed forwards by the rollers 30 in the direc-tion of rotation of the cylindrical body 29 and thus being pumped forwards. Since the dimension of the tube 27' is known and the speed of rotation of the cylindrical body 29 is controllable, the amount of pumped liquid in the conduit 27 can be very accurately controlled and the flow can be kept very constant. To be able to stop the pump 21 and the mixing process if the flow in the conduit 27 is interrupted, a flow control device 23 is arranged at or in the vicinity of the terminal point of the con-duit 27. The secondary liquid 28 supplied as described above is added to the primary liquid by means of a spe-cially arranged inlet chamber 25 which is shown in detail in Fig. 2. The inlet chamber 25, which is connected to the conduit 26 for primary liquid, is provided with a connecting flange 32, which is located in the position where the conduit 26 in the case shown makes a bend and, in the bend of the conduit, has a liquid-flow-conducting labyrinth 31 for guiding the flow of primary liquid towards the inlet chamber 25. The inlet chamber 25 is provided with a connecting flange 33, which matches the conduit flange 32 and which is provided with seals 34 closely connected to each other. The inlet chamber 25 also has spaces 35, which can be kept sterile by means of a sterilising agent, e.g. vapour or a sterilising liquid, supplied through the conduit 10. The passing vapour or liquid sterilises the spaces 35 and all the objects that are present or may be present in the spaces 35. Moreover, the inlet chamber 25 has one or more spaces 14, which are adapted to receive injection needles or syringe-like can-nulae comprising a hypodermic needle 12 and a connection 36 to the conduit 27.
As shown in Fig. 2, the inlet chamber 25 may be pro-vided with several spaces 14 for hypodermic needle ar-rangements which, adjacent to said connection 36, are sealed against the inlet chamber 25 by means of a sealing ring 37 of 0 ring type.
The cannula 12 is thus displaceably movable in the chamber 14 by displacing the connection 36 with the seal-ing ring 37. That part of the inlet chamber 25 which con-nects to the primary liquid conduit 26 has a sealing wall 38 made of rubber or a rubber-like material, which can easily be penetrated by the cannula 12 and which, after retraction of the cannula 12 into the space 14, in a self-sealing manner attaches itself around the hole made by the cannula 14 in the sealing wall 38. Thus, the can-5 nula 12 can, when positioned in the space 14, be steril-ised and be made to retain its sterility to be passed through the sealing wall 38 into the conduit 26 for sup-plying, in an accurately predetermined dose, secondary liquid 28 to the flowing primary liquid. The cannula 12 can also be retracted into the space 14 without interrup-tion of the sterility. As shown, the connection 36 to the cannula 12, 13 is provided with a flange 39. After inser-tion of the cannula 12, 13 into the conduit 26, the can-nula 12, 13 can be locked in the inserted position by a stop flange 40 being pushed over the flange 39, the posi-tion of the cannula 12 and the associated connection 36 being fixed. To achieve a good mixing of primary liquid and secondary liquid or secondary liquids, the conduit 26' for the mixed liquids is provided with a mixing cham-ber 24 having surfaces deflecting the flow of liquid to achieve, under turbulent flow, a homogeneous mixing of the joined liquids. Fig. 3 shows an example of the above-described bag 19 for secondary liquid, and as is obvious, the bag is provided with two connections 27, 3, the con-nection 3 constituting the filling conduit and the tube 27, as described above, constituting the discharge con-duit for secondary liquid. Of course, the tank for secon-dary liquid 19 need not necessarily be a plastic bag but may be a more dimensionally stable vessel made of plastic or metal, and it is not necessary to the invention that the supplied secondary liquid or, for that matter, the primary liquid be a sterile liquid.
It should be added that in the cases where several secondary liquids are to be supplied, not only the inlet chamber must be provided with several chambers and cannu-lae for secondary liquid 28, but also that each secondary liquid 28 necessitates its own storage tank 19, its own pump 21 and its own regulator 20, unless the secondary liquids are not of such a nature that even in the storage tank they can be mixed to a common "secondary liquid mix-ture". An inlet chamber with a number of cannula posi-tions may be practical to use with a view to making it possible to stop the process without shifting from a secondary liquid tank 19 to another when the first tank is empty. Such a "flying shift" of the secondary liquid tank 19 is possible to perform if the inlet chamber 25 is provided with several cannula spaces in the manner as described above.
It has been found that the device according to the present invention results in a permanent, very exact mix-ing ratio also during long continuous operation even if the volume ratio when mixing the liquids is extremely nonuniform.
As mentioned, it is also possible to mix, under uninterruptedly aseptic conditions, sterile liquids, and it is also easy during the mixing operation, if desired, to adjust the mixing ratio with very great accuracy.
FLOWING PRIMARY LIQUID WITH ONE OR MORE ADDED
SECONDARY LIQUIDS
The present invention relates to a dosing device or mixing device for mixing, in a continuous process, a flowing primary liquid with one or more added secondary liquids for obtaining a flowing liquid mixture at a per-manent, uniform mixing ratio of the mixed liquids. Espe-cially the processing industry and medicinal technology require access to dosing devices, by means of which two or more components in liquid state are continuously mix-ed with each other under conditions which yield uniform mixing ratios, i.e. uniform amounts of the components included, in a continuous mixing process. The device and the method according to the invention are especially applicable in the cases where one or some components, so-called secondary components, are to be admixed to a flow-ing primary component and where the amount of secondary components in terms of volume is comparatively small or very small compared with the amount of the primary compo-nent in the finished mixture. In some cases, it is thus desirable to add enzymes, colourants, flavouring agents, vitamins etc. In a flowing quantity of liquid, the con-tent of the added substances, the so-called secondary components, can be as low as 0.05-l0 of the flowing pri-mary component. It is possible by using the inventive method to obtain, with a uniform and continuous mixing ratio, a flow of liquid which can proceed to be packed with an equal content of additives in all packings. An ' example of such a process is, for instance, the prepara-tion of lactose-free sterile milk, where the untreated sterilised and lactose-containing milk is continuously mixed with a quantity of sterile-filtered lactase before packing, the proportions of lactose-containing milk/lac-tase being in the order of 5-10,000, about the same mix-ing ratio being required in all packings that are conti-nuously prepared. In some other cases, higher contents of secondary liquid are required as addition, for instance when colouring or flavouring foodstuffs.
Dosing equipment for mixing flows of liquid having different flow ratios is known, but such equipment has essentially been directed to obtaining a constant mixing ratio by letting the combined flows of liquid being join-ed and conducted in a loop, i.e. a certain part of the flow of liquid is deflected from the main conduit and recirculated to a point in the flow conduit which is positioned downstream. The mixed liquid or parts thereof will in this manner circulate several times through the loop to obtain a good mixing when the loop has finally been passed. The present invention, which operates with-out a mixing loop, is considerably simpler in its techni-cal design and permits great flexibility as regards the amount and type of additives and is, above all, easier to adjust between the use of different mixing components.
The dosing device according to the invention preferably is adapted to be used in the foodstuff industry but may also be used in medicinal industry for continuous mixing of components in liquid state.
An embodiment of the invention will be described below with reference to the accompanying schematic drawing, in which Fig. 1 illustrates the dosing device, Fig. 2 illustrates a special device with a plurality of needle-like nozzles for supplying a secondary liquid and Fig. 3 shows a flexible plastic bag for storing steri-lised secondary liquid. As mentioned above, the described device comprises a means for mixing, with great accuracy to volume, a first liquid, here called primary liquid, with the second liquid, here called secondary liquid, the mixing ratio being such that there is a very great difference between the individual volumes of the mixed liquids. As pointed out above, in many medicinal pro-cesses but also in connection with other processes, for instance, colouring of a liquid or adding of e.g. enzymes or flavouring agents to a liquid, there is a need of add-ing a smaller amount of secondary liquid to an essential-ly larger amount of primary liquid. In a continuous mix-ing process, it is most important that the mixing ratio, in spite of the differences in volume between the mixed liquids, is constant and controllable all the time during the process, such that, for instance, the flavour or the enzyme content of the resulting mixed liquid will not vary.
The apparatus shown in Fig. 1 consists of a flow pipe 26 for primary liquid, the amount of passing primary liquid being controllable by means of a flow meter 22, which registers the amount of passing primary liquid and which by means of the regulator 20 controls the speed of the peristaltic pump 21. In the case shown, the secondary liquid is taken from a plastic bag 19 containing, in this case, sterilised secondary liquid 28. The secondary liquid 28 is passed via the conduit 27 to a peristaltic pump 21 controlled by the regulator 20 and being of known type, comprising a rotatable cylindrical body 29, which at its circumference supports rollers 30, which in the case shown are positioned diametrically opposite each other in the cylindrical body 29, and which with its rollers projects outside the periphery of the rotatable body 29. At least part 27' of the conduit 27 is made of a flexible material, e.g. rubber or plastic, and this part 27' of the conduit 27 is arranged in a duct 31 of the pump 21.
During rotation of the cylindrical body 29, the flexible conduit 27' is compressed by the rollers 30, the liquid contained in the conduit 27' between the rollers 30 being pressed forwards by the rollers 30 in the direc-tion of rotation of the cylindrical body 29 and thus being pumped forwards. Since the dimension of the tube 27' is known and the speed of rotation of the cylindrical body 29 is controllable, the amount of pumped liquid in the conduit 27 can be very accurately controlled and the flow can be kept very constant. To be able to stop the pump 21 and the mixing process if the flow in the conduit 27 is interrupted, a flow control device 23 is arranged at or in the vicinity of the terminal point of the con-duit 27. The secondary liquid 28 supplied as described above is added to the primary liquid by means of a spe-cially arranged inlet chamber 25 which is shown in detail in Fig. 2. The inlet chamber 25, which is connected to the conduit 26 for primary liquid, is provided with a connecting flange 32, which is located in the position where the conduit 26 in the case shown makes a bend and, in the bend of the conduit, has a liquid-flow-conducting labyrinth 31 for guiding the flow of primary liquid towards the inlet chamber 25. The inlet chamber 25 is provided with a connecting flange 33, which matches the conduit flange 32 and which is provided with seals 34 closely connected to each other. The inlet chamber 25 also has spaces 35, which can be kept sterile by means of a sterilising agent, e.g. vapour or a sterilising liquid, supplied through the conduit 10. The passing vapour or liquid sterilises the spaces 35 and all the objects that are present or may be present in the spaces 35. Moreover, the inlet chamber 25 has one or more spaces 14, which are adapted to receive injection needles or syringe-like can-nulae comprising a hypodermic needle 12 and a connection 36 to the conduit 27.
As shown in Fig. 2, the inlet chamber 25 may be pro-vided with several spaces 14 for hypodermic needle ar-rangements which, adjacent to said connection 36, are sealed against the inlet chamber 25 by means of a sealing ring 37 of 0 ring type.
The cannula 12 is thus displaceably movable in the chamber 14 by displacing the connection 36 with the seal-ing ring 37. That part of the inlet chamber 25 which con-nects to the primary liquid conduit 26 has a sealing wall 38 made of rubber or a rubber-like material, which can easily be penetrated by the cannula 12 and which, after retraction of the cannula 12 into the space 14, in a self-sealing manner attaches itself around the hole made by the cannula 14 in the sealing wall 38. Thus, the can-5 nula 12 can, when positioned in the space 14, be steril-ised and be made to retain its sterility to be passed through the sealing wall 38 into the conduit 26 for sup-plying, in an accurately predetermined dose, secondary liquid 28 to the flowing primary liquid. The cannula 12 can also be retracted into the space 14 without interrup-tion of the sterility. As shown, the connection 36 to the cannula 12, 13 is provided with a flange 39. After inser-tion of the cannula 12, 13 into the conduit 26, the can-nula 12, 13 can be locked in the inserted position by a stop flange 40 being pushed over the flange 39, the posi-tion of the cannula 12 and the associated connection 36 being fixed. To achieve a good mixing of primary liquid and secondary liquid or secondary liquids, the conduit 26' for the mixed liquids is provided with a mixing cham-ber 24 having surfaces deflecting the flow of liquid to achieve, under turbulent flow, a homogeneous mixing of the joined liquids. Fig. 3 shows an example of the above-described bag 19 for secondary liquid, and as is obvious, the bag is provided with two connections 27, 3, the con-nection 3 constituting the filling conduit and the tube 27, as described above, constituting the discharge con-duit for secondary liquid. Of course, the tank for secon-dary liquid 19 need not necessarily be a plastic bag but may be a more dimensionally stable vessel made of plastic or metal, and it is not necessary to the invention that the supplied secondary liquid or, for that matter, the primary liquid be a sterile liquid.
It should be added that in the cases where several secondary liquids are to be supplied, not only the inlet chamber must be provided with several chambers and cannu-lae for secondary liquid 28, but also that each secondary liquid 28 necessitates its own storage tank 19, its own pump 21 and its own regulator 20, unless the secondary liquids are not of such a nature that even in the storage tank they can be mixed to a common "secondary liquid mix-ture". An inlet chamber with a number of cannula posi-tions may be practical to use with a view to making it possible to stop the process without shifting from a secondary liquid tank 19 to another when the first tank is empty. Such a "flying shift" of the secondary liquid tank 19 is possible to perform if the inlet chamber 25 is provided with several cannula spaces in the manner as described above.
It has been found that the device according to the present invention results in a permanent, very exact mix-ing ratio also during long continuous operation even if the volume ratio when mixing the liquids is extremely nonuniform.
As mentioned, it is also possible to mix, under uninterruptedly aseptic conditions, sterile liquids, and it is also easy during the mixing operation, if desired, to adjust the mixing ratio with very great accuracy.
Claims (17)
1. A dosing device for mixing, in a continuous process, a flowing primary liquid with one or more secondary liquids of an essentially smaller quantity (0.05-1 %) for obtaining a flowing liquid mixture at a constant uniform mixing ratio of the mixed liquids, the dosing device comprising:
a flow pipe for carrying the primary liquid;
a mixing chamber;
at least one storage tank for a secondary liquid;
at least one narrow nozzle;
at least one pump for continuously supplying the second liquid to the mixing chamber via each narrow nozzle including a needle-like tube movable between a retracted position and an inserted position;
the mixing chamber having a penetrable flexible wall part through which the needle-like tube is insertable.
a flow pipe for carrying the primary liquid;
a mixing chamber;
at least one storage tank for a secondary liquid;
at least one narrow nozzle;
at least one pump for continuously supplying the second liquid to the mixing chamber via each narrow nozzle including a needle-like tube movable between a retracted position and an inserted position;
the mixing chamber having a penetrable flexible wall part through which the needle-like tube is insertable.
2. A dosing device as claimed in claim 1, wherein the inserted position of each nozzle is located in parallel with the flow path of the primary liquid and centrally arranged therein.
3. A dosing device as claimed in claim 1, wherein each nozzle includes injection-needle-like devices having an obliquely cut-off pointed portion and having inlet openings provided with connecting means for connecting the injection needle-like devices to tubes or conduits for supplying secondary liquid.
4. A dosing device as claimed in claim 1, wherein each storage tank includes one of a sterilized bag or non-yielding container made of a flexible plastic material or metal, and each storage tank holds a sterile liquid.
5. A dosing device as claimed in claim 4, wherein each storage tank includes two connection ducts in the form of tubes or conduits, which communicate with the interior of the tank and of which one is a supply duct and the other is a liquid-discharging duct, each of the connection ducts being adapted to permit separate closing and opening.
6. A dosing device as claimed in claim 1, wherein each pump comprises a peristaltic pump with infinitely variable adjustment of the pump capacity.
7. A dosing device as claimed in any one of claim 6, further comprises a flow meter for measuring the flow of the flowing primary liquid in said flow pipe, and a regulator which, controlled by said flow meter for regulating the speed of rotation and, thus, the flow from said peristaltic pump in such manner that at least one of the secondary liquids are admixed to the flowing primary liquid in a controllable manner and in a controllable quantity.
8. A dosing device as claimed in claim 1, further comprises a sterile filter arranged in the connection duct between said tank for secondary liquid and said nozzle for supplying secondary liquid to said primary liquid.
9. A dosing device as claimed in claim 1, wherein the mixing chamber has a plurality of deflection parts located in the flow pipe and adapted to deflect the direction of flow for partial amounts of said primary liquid and said supplied secondary liquids for the purpose of producing a turbulent flow and obtaining a homogeneous mixing of the liquids supplied.
10. A dosing device as claimed in claim 1, wherein the flexible and penetrable wall part has a space through which a sterilizing liquid can flow at least during insertion of the needle-like tube, for surrounding or flowing around parts of said needle-like tube.
11. A dosing device as claimed in claim 10, wherein an insertion part of said nozzle has a space, which is filled with sterilizing liquid or is passed thereby and which has an outlet wall made of a penetrable, flexible material, preferably rubber or a rubber-like material, the needle-like tube, before penetration of the outlet wall of said space, being surrounded by or flushed with sterile liquid, and that the nozzle, through further movement in the longitudinal direction of the nozzle, is caused to penetrate said outlet wall for penetrating, with its sterilized needle-like tube, into said flow pipe.
12. A dosing device as claimed in claim 1, wherein a connection means for supplying secondary liquid, comprises a holder connected to said flow pipe and receiving each nozzle, said holder having at least two guide sleeves adapted to support and longitudinally guide the position of two nozzles, each needle-like tube being slidably attached in said sleeves which are sealingly arranged against a space, that the interior of said sleeves or spaces in their longitudinal extension each open at the flexible and penetrable wall made of a rubber-like material, said wall separating said spaces from the interior of said flow pipe, said needle-like tubes being individually operable in their sleeves in such manner that, independently of each other, they can be moved in a longitudinal direction of the nozzles and be caused to penetrate said flexible wall part for the purpose of locating the point of the needle-like tube in the flow pipe for the purpose of supplying said secondary liquid to said primary liquid.
13. A method of mixing two or more liquids in a continuous process, comprising the steps of:
flowing a primary liquid through a mixing chamber;
introducing a secondary liquid into the mixing chamber, via a needle-like nozzle, at a constant rate in order to produce a mixture at a constant uniform mixing ratio with the secondary liquid having an essentially smaller quantity (0.05-1%).
flowing a primary liquid through a mixing chamber;
introducing a secondary liquid into the mixing chamber, via a needle-like nozzle, at a constant rate in order to produce a mixture at a constant uniform mixing ratio with the secondary liquid having an essentially smaller quantity (0.05-1%).
14. A method as claimed in claim 13, wherein said primary liquid consists of foodstuffs or medicinal products.
15. A method as claimed in claim 14, comprising the step of sterilizing said primary liquid.
16. A method as claimed in claim 14, comprising the step of pasteurizing said primary liquid.
17. A method as claimed in claim 14, wherein the secondary liquid consists of at least one of enzyme, favouring agents, colourants, vitamins, bacteria or medicinal products.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9602179A SE506791C2 (en) | 1996-06-03 | 1996-06-03 | Dosage device for mixing a flowing primary liquid with one or more secondary liquids and a method for mixing two or more liquids in a continuous process |
| SE9602179-5 | 1996-06-03 | ||
| PCT/SE1997/000965 WO1997046308A1 (en) | 1996-06-03 | 1997-06-03 | Dosing device for mixing in a continuous process a flowing primary liquid with one or more added secondary liquids |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2256650A1 CA2256650A1 (en) | 1997-12-11 |
| CA2256650C true CA2256650C (en) | 2006-04-11 |
Family
ID=36178205
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002256650A Expired - Fee Related CA2256650C (en) | 1996-06-03 | 1997-06-03 | Dosing device for mixing in a continuous process a flowing primary liquid with one or more added secondary liquids |
Country Status (1)
| Country | Link |
|---|---|
| CA (1) | CA2256650C (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014169081A3 (en) * | 2013-04-09 | 2015-05-07 | Biodel, Inc. | Methods and devices for point of use mixing of pharmaceutical formulations |
-
1997
- 1997-06-03 CA CA002256650A patent/CA2256650C/en not_active Expired - Fee Related
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014169081A3 (en) * | 2013-04-09 | 2015-05-07 | Biodel, Inc. | Methods and devices for point of use mixing of pharmaceutical formulations |
Also Published As
| Publication number | Publication date |
|---|---|
| CA2256650A1 (en) | 1997-12-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| MKLA | Lapsed |
Effective date: 20150603 |