CA2254554A1 - Nouveaux liposomes sans phospholipide modifies a l'aide d'un copolymere sensible au ph et a la temperature - Google Patents

Nouveaux liposomes sans phospholipide modifies a l'aide d'un copolymere sensible au ph et a la temperature Download PDF

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Publication number
CA2254554A1
CA2254554A1 CA002254554A CA2254554A CA2254554A1 CA 2254554 A1 CA2254554 A1 CA 2254554A1 CA 002254554 A CA002254554 A CA 002254554A CA 2254554 A CA2254554 A CA 2254554A CA 2254554 A1 CA2254554 A1 CA 2254554A1
Authority
CA
Canada
Prior art keywords
amino acid
liposome
liposomes
cholesterol
phospholipid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002254554A
Other languages
English (en)
Inventor
Alla Polozova
Francoise M. Winnik
David W. Andrews
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
McMaster University
Original Assignee
McMaster University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by McMaster University filed Critical McMaster University
Priority to CA002254554A priority Critical patent/CA2254554A1/fr
Priority to CA002290333A priority patent/CA2290333A1/fr
Publication of CA2254554A1 publication Critical patent/CA2254554A1/fr
Abandoned legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
    • A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers with substantial amounts of non-phosphatidyl, i.e. non-acylglycerophosphate, surfactants as bilayer-forming substances, e.g. cationic lipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
    • A61K9/1273—Polymersomes; Liposomes with polymerisable or polymerised bilayer-forming substances
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F220/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
    • C08F220/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
    • C08F220/52—Amides or imides
    • C08F220/54—Amides, e.g. N,N-dimethylacrylamide or N-isopropylacrylamide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Dispersion Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA002254554A 1998-11-20 1998-11-20 Nouveaux liposomes sans phospholipide modifies a l'aide d'un copolymere sensible au ph et a la temperature Abandoned CA2254554A1 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
CA002254554A CA2254554A1 (fr) 1998-11-20 1998-11-20 Nouveaux liposomes sans phospholipide modifies a l'aide d'un copolymere sensible au ph et a la temperature
CA002290333A CA2290333A1 (fr) 1998-11-20 1999-11-19 Nouveaux liposomes sans phospholipide modifies a l'aide d'un copolymere sensible au ph et a la temperature

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CA002254554A CA2254554A1 (fr) 1998-11-20 1998-11-20 Nouveaux liposomes sans phospholipide modifies a l'aide d'un copolymere sensible au ph et a la temperature

Publications (1)

Publication Number Publication Date
CA2254554A1 true CA2254554A1 (fr) 2000-05-20

Family

ID=29425725

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002254554A Abandoned CA2254554A1 (fr) 1998-11-20 1998-11-20 Nouveaux liposomes sans phospholipide modifies a l'aide d'un copolymere sensible au ph et a la temperature

Country Status (1)

Country Link
CA (1) CA2254554A1 (fr)

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Legal Events

Date Code Title Description
FZDE Discontinued