CA2240456A1 - Self-locking holding device with single-point fixation - Google Patents

Self-locking holding device with single-point fixation Download PDF

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Publication number
CA2240456A1
CA2240456A1 CA002240456A CA2240456A CA2240456A1 CA 2240456 A1 CA2240456 A1 CA 2240456A1 CA 002240456 A CA002240456 A CA 002240456A CA 2240456 A CA2240456 A CA 2240456A CA 2240456 A1 CA2240456 A1 CA 2240456A1
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CA
Canada
Prior art keywords
holding device
fins
hole
locking
piece
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002240456A
Other languages
French (fr)
Inventor
Adriano Vigano
Rene Bernays
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MAGNETIC VISION GmbH
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2240456A1 publication Critical patent/CA2240456A1/en
Abandoned legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/10Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges for stereotaxic surgery, e.g. frame-based stereotaxis
    • A61B90/11Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges for stereotaxic surgery, e.g. frame-based stereotaxis with guides for needles or instruments, e.g. arcuate slides or ball joints
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/34Trocars; Puncturing needles
    • A61B17/3417Details of tips or shafts, e.g. grooves, expandable, bendable; Multiple coaxial sliding cannulas, e.g. for dilating
    • A61B17/3421Cannulas
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/34Trocars; Puncturing needles
    • A61B2017/348Means for supporting the trocar against the body or retaining the trocar inside the body
    • A61B2017/3482Means for supporting the trocar against the body or retaining the trocar inside the body inside
    • A61B2017/3484Anchoring means, e.g. spreading-out umbrella-like structure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/10Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges for stereotaxic surgery, e.g. frame-based stereotaxis
    • A61B2090/103Cranial plugs for access to brain
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/02Access sites
    • A61M39/0247Semi-permanent or permanent transcutaneous or percutaneous access sites to the inside of the body

Landscapes

  • Health & Medical Sciences (AREA)
  • Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Molecular Biology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medical Informatics (AREA)
  • Pathology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Surgical Instruments (AREA)
  • Prostheses (AREA)
  • Connection Of Plates (AREA)

Abstract

The insert (4) of the holding device possesses fins (4b) that are arranged according to the shape of a hole so that, after being introduced into the hole, they are form-fitting, and make the hooks (4c) engage at the edge of the hole. The locking piece (3), which fits non-positively to the inside of the fins (4b), fixes the fins (4b) in position. The locking piece (3) in turn is prevented from slipping out unintentionally by the fixing piece (1). Depending on the embodiment, a pretensioning wheel (5) can increase the hold and allow adjustment to different wall thicknesses (7), and a guide sleeve (2) can enable intruments (6) to be guided precisely.

Description

WO 9~/17191 PCT/CH97/OO~a6 SELF-LOCKING HOLDING DEVICE WI~H SI~GLE-POI~ ~IXATION

The invention relate~ to a holding device according to ~he preamble of Claim 1. This holding device can be u~ed in many different fields.

One po~eible field of application is the field of medicine;
for example, for maklng a biopsy in the field of neuro~urgery.
In neurosurgery, biop~ie~ are generally per~ormed a~ stereotaxic su~gery. In the ca~e of stereotaxic ~urgery, the biop~y path is de~ined by meane of the trepanation point and target determined ~y the ~urgeon.

For conventional ~tereotaxy, ~tereo~axy ring~ and target bow~ are u~ed (~or example, the Kelly Sy~tem, Riechert ~
Mundinger, CRW, BRW; ~ee al~o: "Neuro~urgery", R.H. Wilkin~ and S . S . Rengachary, 2nd Edition 1996, Volume III, Pages 4067, and on, where a good overview of the present ~3tate of the art i~
found. ) The~e require a multi-point fixation in the tabula externa of the skull cap ( exterior layer o~ the cranial bone).
Thi~3 thus fixed ~tereotaxy ring must be worn by the patient for ~e~reral hours which repre6ents a conE3iderable ~3train eo the patient . In addition, the stereot~xy system limits the surgeon ' 9 operat lve act ion radiu~ .

~ he ln~ention sol~es tank~, for example, in the field of neuro~urgery which arl~e a~ the result of the further de~elopment of the nuclear ~p$n tomograph or magnetic resonance ima~ing ~y~tem (MR~) to the interventional magnetic re~onance imaging ~ystem (IMR). The IMR produce~ real-time high-quality tomograms 0~ the body and, a~3 a pion~ering innovation, permit~ rgery on a patient wh~le ~enerating imagee. In contra~t, in the ca-qe of conventional ~tereotaxy, individual image~ produced before the eurgery are u~ed a~ design fundame~tal~ for planning ~he surgery.
This method i~ unable to take into account change~ between the generat ing of the tomogran~ and the surgery.

The fixed auxiliary reference sy~tem created and reguired by the conventional ~tereo'caxy method i8 no longer required in the IMR becau~e, during the whole surgical procedure, the patient lB
situated in the IMR with the reference system defined by the fla~h point ~y~tem (FPS) auxiliary device connected to the IMR.

The FPS i8 a two- or three-LED guide who~e po!3ition in the three-dimeneional ~pace is detected by three cameraE~. The FPS
allow~ the planning of a ~urgical procedure by defining an axi~3 which is computed into the lmage generated by the IMR and i~
displayed on a monitor in an i~ochronou~ manner.

The virtual axi~ generated by the FPS is made congruent wit~
t}-e biop~y path. It i~ now an object to maintain the found ~ CA 02240456 1998-06-22 biop~y axl~ by a ~ixation of the FPS in the three-dimensional space. The manufacturer of the FPS conceived this for a fixation on a gooseneck. However, the goo~eneck~ known ~o far permit no rellable fixation.

The lnvention permit~ a perfect fixation in the three-dimen~ional ~pace becauce, in the case of the ~elected exa~ple, it i~ fixed to the patient'~ skull cap. Furthermore, the invention requires only little space and reduce~ the inconvenience and ~urgery-caused etre~ to the patient to a minimum.

The object i~ achieved according to the invention by mean~
of the feature~ indicated in the characterizing part of Claim 1.

Figure~ 1 to 18 illu~trate an embodiment of the invention in the field of medicine. A~3 an example, an MR-compa~ible con~truction was selected for a biop~y in the field of neuro~urgery.

Figure 1 is an exploded view of the holding device;

Figure 2 ie a view of the assembled holding device in~erted into the ~kull ~ap 7 with an introduced biop~y needle 6;

Figure 3 i~ an exploded ~iew of the localizer;

Figure 4 i8 a view of an a~;~embled localizer with an applied FPS 10;

Figure 5 i~ a v~ ew of a ra~;

Figure 6 i~ an exploded view ~f the combined in~trument of the dura detaching in~trument and the mea~uring device;

Figure 7 iB a view c1f an a~;sembled combined in~trument;

Figure ~ i~ an exploded view of the locking sleeve remo~er;

Figure 9 i~ a view of the a~embled locking ~leeve remover;

Figure~ 10 to la illustrate a possible ~ouxse o~ an applicatlon o~ the in~ention.

Figure 10 i~ a view of an insext 4 and a preten~ioning wheel 5 which are screwed together before ~eing in~erted into the ~kull cap 7;

Figure 11 iH a view of t~e in~3ert 4 and the pretensioning wheel 5 ineerted into the ~kull cap 7;

Figure 12 i~ a view of the locking sleeve 3 in~erted by mean~ of the ram ll;

Figure 13 i8 a view of the fixing wheel l and the guide ~leeve 2 whlch are in~erted into the in~er~ 4;

Figure 14 in a view of the holding device which i~ inserted in an assembled and operationally ready manner into the ~kull cap 7, 1/4 ~ectional view with the ineerted biop~y needle 6;

Figure 15 i~ a view of the locking :3leeve remover in the relaxed condition before the removal of the locking sleeve 3;

Figure 16 i~ a ~iew of the locking sleeve remover which i~
engaged ln the locking E~leeve 3 but not locked;

Fiqure 17 i~ a view of the lockin~ sleeve remover which i~
locked by pre~sure on the head lSa;

~ igure 18 i~ a view of the removal of the locking nleeve 3.

In the following, the production and u~e of the invention i~
lllu~trated by mean~ of an embodiment from the field of neurosurge~y.

For thl~ field of application, it i~ u~eful to produce the invention of ~ynthetlc material~ (PEEK, POM) in order to prevent ~ CA 02240456 1998-06-22 in~erfering artefact formation~ in the IMR.

The invention i~ ~a~ed on the idea of inserting a ~elf-locking holding device into the bore hole required for brain surgery. In thi~ e~bodiment, the holding de~ice~ ~ses the ~hape o~ a cylindrical bore hole for finding a hold without ha~ing to u~e third fixation point~.

In order to precinely determine the ~pot where the bore hole i~ to be made, the FPS 10 is placed on the target pin 9 of the localizer (Figure 4). The localizer i~ a~embled a~ illu~trated in Figure 3. In this ca~e, the ball-and-socket joint of the target pin gb i8 guided by the upper la and lower 8c joint eocket~ contained in the fixing wheel 1 and in the localizer ~tand 8. T~e ~wivelling radiu~3 of the target pin 9 is limited by t~e conlcal interior surface of the fixing piece 1 in a manner uqed later for the limiting of the guide sleeve in the fixing wheel 1. The target pin 9 can be fixed in it~ position by the clo~ing of the ~ixing wheel 1.

The locallzer i8 now held by means of the pedicles 8a againnt the patient ' 8 head and i8 moved around until the target pin 9 or the axi~ calculated ~y the FPS point to the site to be operaeed. The flexible pedicle~ 8a now make lt po~sible by mean~
of a pre~ing onto the localizer, to pre~-~ the central ~arker ~b onto the ~calp and thu~ mark the point were the drilling i8 to be ~ CA 02240456 1998-06-22 carried out. The drill and the outer radiu6 o~ the fin~ 4b are ~elected ~o have the same ~ize.

After the placing of the cylindrical ~ore hole (normally of a diameter of lS mm) in the ~kull cap 7, by mean~ of a dura detaching device 12, the menin~ iB detached from the intexior ~ide of the skull cap 7 (Figure 6). ~hen, by mean~ of the mea8u~emen~ ~cale 12a pro~ided on the dura detaching device 12, the thickness of the 8kull cap 7 ~an be meaeured (Figure 7) and thus the opti~al ~ize of the in~ert 4 can be selected. When ~he in~ert 4 is guided through the bore hole, the flexible ~ins 4b are compressed by the projecting small hook~ 4c to a smaller radiu~. After the ~all hook~ 4c of the insert 4 have reached the interior ~ide of the ~kull, the flexi~le ~in~ 4b will ~prin~
baek into their ini~ial po~ition, whereby the small hook~; 4c are pres~ed over the ed~e of the bore hole (Figure 10 and Figure 11) and prevent a ~liding back of the holding device out of the bore hole. After they were guided through the bore hole, the flexible fins 4b, which are arranged in a ring-~haped manner on the in~ert 4, rent flu~h on the bore hole. Then, by mean~ of the ram 11, the locklng ~leeve 3 i8 in~erted into the insert 4 (Fiyure 12).
By means o~ it~ fit with the inside radiu~3 of the flexiblc fin~
4a, the locking 81eeve 3 prevent~ another ~p~inging-back of the fins. By ~ean~ of the clo8ing of the preten~ioning wheel S, the ~kull cap 7 is now clamped in between the ~all hoo~s 4b and the pre~en~ioning wheel 5. The preten~ioning wheel S permits the ~ CA 02240456 1998-06-22 taklng into account of different wall thicknesues of the ~kull 7.

The locking sleeve 3, in turn, is fixed in it~ po8i~ion by the screwing-on of the fixing wheel 1.

The locking ~leeve 3 and the ecrewed-on fixing wheel 1 form the upper la and the lower 3a integrated joint socket~ for the ball-and-so~ket joint of the guide sleeve 2b. By mean~ of thi~
joint 2b, the guide ~leeve 2 can be ~wivelled in a ~electable radiuY. Cones are therefore rece~sed in the axis of the guide eleeve ~ in the fixing wheel 1 and the locking sleeve 3. As ~oon as the guide ~leeve 2 ha~ reached the de~ired position, by me~n~
of a rotatlng on the fixing wheel 1, the guide ~leeve 2 can be fixed in it~ ponition ~igure 13, 14). ~ow, the biop~y needle 8 can be introduced lnto ~he guide ~leeve 2 and the specimen can be taken ( Figure 14).

The fixing wheel 1 i~ unRcrewed ~or removing the holding device. Then, by means of the locking sleeve remover ( F'igure ~, 9), the locking fileeve 3 i8 removed (Figures 15 to 18) . ~n the ~tarting position, the pin of the locking ~leeve remover 15 i~
preu~ed ~o the upper ~top of he locking pin l5b in the pln detent 14c. Thu~, the locking ~leeve remover can be introduced into the locking sleeve 3, becau~e the expan~ion fin~ 14b can be compre~ed ~Figure 15, 16~ By a pre~ing onto the head ~Sa of the locklng ~leeve remover, the expansion f in~ 14b are fixed ln thelr po~ition (Fig. 17, 19) ~o that ehe locking ~leeve 3 can be removed. Tl~e ten~ioning wheel S i9 now rotated counterclockwiee, whereby the ~kull ~ap 7 i~ no longer clamped in. sy mean~ of a ~light rotatlng and tilting movement, the insert 4 can he removed f rom the bore hole.

Numbering of the Individual Component Parte of the Patent 1 fixing wheel la upper joint ~o~ket lb grip indentation~
2 guide ~leeve 2a adapter for FPS (Fla~h Point System 2b ball-and-~ocket joint of the guide sleeve 3 locking ~leeve 3a lower joint socket 3b ineide cone of the locking ~leeve 4 ineert 4a grip ~ndentation~
4b flne 4c ~mall hook~
4d ~in elot~

preten~ioning wheel 5a out~ide cone of the preten~ioning wheel Sb grip indentations 6 biop~y needle 7 ~kull cap 3 localizer eupport ~a pedlcle Bb central marker 8c lower ~oint ~ocket g target pin 9a adapter $or FPS
9b ball-and-~ocket joint for target pin fla~h point system (FPS) ram 12 dura detaching device 12a mea~urement ~cale 12b underminlng head 13 meaeuring ~leeve jacket of the locking slee~e remover (VHE) 14a guide bore 14b Yr~nRion fin~
l~c pin detent pin of the locking ~leeve remover (VHE) 15a head 15b detent pin 6 pre~E~ure ~pring

Claims (9)

CLAIMS:
1. Self-locking holding device with single-point fixation, characterized in that it has fins having hooks arranged corresponding to the shape of a hole on the insert such that, after being inserted into the hole, the fins 4b rest form-lockingly against the hole and the small hooks 4c and let the small hooks 4c project beyond the outer edge of the hole on the side of the hole facing away from the holding device, the subsequent inserting of the locking piece 3, which fits force-lockingly on the interior side of the fins, fixing the fins in their position, the clamping effect between the small hook 4c, the fine 4b and the insert bottom 4e ensuring the hold, the inserting of a fixing piece 1 preventing the unplanned sliding-out of the locking piece 3.
2. Holding device according to Claim 1, characterized in that the fixing piece has an adapter for holding or guiding.
3. Holding device according to Claim 1, characterized in that the insert has fins 4b arranged in a ring shape and a round locking sleeve 3 so that it can be inserted into a round hole.
4. Holding device according to one of Claims 1 to 3, characterized in that it has a pretensioning wheel 5, the holding device thus being adaptable to different wall thicknesses, and the hold being increased by the clamping in of the wall between the small hooks and the pretensioning wheel.
5. Holding device according to one of Claims 1 to 4, characterized in that a guide piece 2 is mounted between the fixing piece 1 and the locking piece 3.
6. Holding device according to Claim 5, characterized in that the guide piece 2 can be swivelled.
7. Holding device according to Claim 1 to 6, characterized in that the guide piece 2, the insert 4 and the locking piece 3 each have a mutually aligned hole which permits the guiding-through of instruments, tubes, hoses, etc.
8. Arrangement for carrying out the process according to Claim 3 and 8, arrangement for removing the locking sleeve 3, characterized in that expansion fins 14b are arranged on the jacket of the remover 14 such that, after the insertion into a recess in the locking piece 3, they rest form-lockingly on the interior side of the locking piece 3, a pin 15 then fixing the expansion fins 14b and permitting the pulling of the locking piece out of the insert.
9. Arrangement for carrying out the process according to one of Claims 1 to 7 for use with an instrument for determining the correct location of the bore hole, characterized in that the target pin 9 and the fixing piece 1 with respect to their mobility and construction, correspond to the corresponding parts of the subsequently used holding device, the flexible pedicles 8a, in addition, allowing the pressing of the central marker onto the desired spot.
CA002240456A 1996-10-23 1997-10-13 Self-locking holding device with single-point fixation Abandoned CA2240456A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH258796 1996-10-23
CH2587/96 1996-10-23

Publications (1)

Publication Number Publication Date
CA2240456A1 true CA2240456A1 (en) 1998-04-30

Family

ID=4237144

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002240456A Abandoned CA2240456A1 (en) 1996-10-23 1997-10-13 Self-locking holding device with single-point fixation

Country Status (7)

Country Link
EP (1) EP0884980A1 (en)
JP (1) JP2000502279A (en)
AU (1) AU4449397A (en)
CA (1) CA2240456A1 (en)
IL (1) IL125084A0 (en)
NO (1) NO982899L (en)
WO (1) WO1998017191A1 (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016178857A1 (en) * 2015-05-01 2016-11-10 Musc Foundation For Research Development Cranial anchoring and positionings system and method
US20170151032A1 (en) * 2015-11-30 2017-06-01 Penumbra, Inc. System for endoscopic intracranial procedures
US11446111B2 (en) 2017-03-24 2022-09-20 Musc Foundation For Research Development Cranial anchoring and positioning system and method
US11944506B2 (en) 2016-04-15 2024-04-02 Stryker European Operations Holdings Llc Methods of setting a cannula lock

Families Citing this family (13)

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US5993463A (en) * 1997-05-15 1999-11-30 Regents Of The University Of Minnesota Remote actuation of trajectory guide
EP1029509A1 (en) 1999-02-19 2000-08-23 Magnetic Vision GmbH Device for cutting and aspirating tissue
US7660621B2 (en) 2000-04-07 2010-02-09 Medtronic, Inc. Medical device introducer
JP4188681B2 (en) * 2000-10-11 2008-11-26 メドカニカ,リミティド ライアビリティー カンパニー Apparatus and system for performing thru-port off-pump coronary artery bypass surgery
DE10214414B4 (en) * 2002-03-30 2004-06-03 Delia Schinkel-Fleitmann Device for fixing a trocar, tube or catheter
US7704260B2 (en) 2002-09-17 2010-04-27 Medtronic, Inc. Low profile instrument immobilizer
US7580756B2 (en) 2004-02-13 2009-08-25 Medtronic, Inc. Methods and apparatus for securing a therapy delivery device within a burr hole
US8961407B2 (en) * 2004-07-21 2015-02-24 Covidien Lp Surgical port assembly
AU2008316640B2 (en) * 2007-10-26 2014-03-06 Boston Scientific Neuromodulation Corporation Burr hole plug designs
EP2537478B1 (en) * 2008-10-07 2014-01-29 Neurendo B.V. A minimal invasive neurosurgery assembly
NL2003831C2 (en) 2009-11-19 2011-05-23 Neurendo B V A shaft connector.
WO2012158254A2 (en) * 2011-05-19 2012-11-22 Synthes Usa, Llc Articulating cranial bolt
ITMI20120663A1 (en) * 2012-04-20 2013-10-21 Promev S R L SUPPORT AND GUIDE DEVICE FOR A SURGICAL INSTRUMENT, IN PARTICULAR FOR NEUROSURGERY

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US3017887A (en) * 1960-01-19 1962-01-23 William T Heyer Stereotaxy device
US4805615A (en) * 1985-07-02 1989-02-21 Carol Mark P Method and apparatus for performing stereotactic surgery
US4809694A (en) * 1987-05-19 1989-03-07 Ferrara Vincent L Biopsy guide
US4998938A (en) * 1988-06-09 1991-03-12 Neurodynamics, Inc. Removable skull mounted work platform and method of assembling same
US5263956A (en) * 1992-03-04 1993-11-23 Neuro Navigational Corporation Ball joint for neurosurgery

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016178857A1 (en) * 2015-05-01 2016-11-10 Musc Foundation For Research Development Cranial anchoring and positionings system and method
US11147646B2 (en) 2015-05-01 2021-10-19 Musc Foundation For Research Development Cranial anchoring and positioning system and method
US20170151032A1 (en) * 2015-11-30 2017-06-01 Penumbra, Inc. System for endoscopic intracranial procedures
US10631946B2 (en) * 2015-11-30 2020-04-28 Penumbra, Inc. System for endoscopic intracranial procedures
US11944506B2 (en) 2016-04-15 2024-04-02 Stryker European Operations Holdings Llc Methods of setting a cannula lock
US11446111B2 (en) 2017-03-24 2022-09-20 Musc Foundation For Research Development Cranial anchoring and positioning system and method

Also Published As

Publication number Publication date
IL125084A0 (en) 1999-01-26
NO982899L (en) 1998-06-23
EP0884980A1 (en) 1998-12-23
AU4449397A (en) 1998-05-15
NO982899D0 (en) 1998-06-22
JP2000502279A (en) 2000-02-29
WO1998017191A1 (en) 1998-04-30

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Legal Events

Date Code Title Description
FZDE Discontinued