CA2239508A1 - Derives benzimidazole substitues par un naphtyle comme anticoagulants - Google Patents

Derives benzimidazole substitues par un naphtyle comme anticoagulants Download PDF

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Publication number
CA2239508A1
CA2239508A1 CA 2239508 CA2239508A CA2239508A1 CA 2239508 A1 CA2239508 A1 CA 2239508A1 CA 2239508 CA2239508 CA 2239508 CA 2239508 A CA2239508 A CA 2239508A CA 2239508 A1 CA2239508 A1 CA 2239508A1
Authority
CA
Canada
Prior art keywords
methyl
optionally substituted
alkyl
halo
piperidin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA 2239508
Other languages
English (en)
Inventor
Steven T. Sakata
Brian D. Griedel
Zuchun Zhao
Kenneth J. Shaw
Damian O. Arnaiz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Berlex Laboratories Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/570,057 external-priority patent/US5849759A/en
Application filed by Individual filed Critical Individual
Publication of CA2239508A1 publication Critical patent/CA2239508A1/fr
Abandoned legal-status Critical Current

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

L'invention concerne de nouveaux composés benzimidazole substitués par un naphtyle et leurs sels acceptables sur le plan pharmaceutique. Cette invention concerne également une composition anticoagulante comprenant ce composé benzimidazole substitué par un naphtyle. Le nouveau composé et les compositions le contenant sont efficaces comme inhibiteurs chez l'homme du facteur Xa ou du facteur IIa et ils sont donc utiles pour le traitement de maladies provoquées par le facteur Xa ou le facteur IIa.
CA 2239508 1995-12-08 1996-12-05 Derives benzimidazole substitues par un naphtyle comme anticoagulants Abandoned CA2239508A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/570,057 US5849759A (en) 1995-12-08 1995-12-08 Naphthyl-substituted benzimidazole derivatives as anti-coagulants
US08/570,057 1995-12-08
PCT/IB1996/001496 WO1997021437A1 (fr) 1995-12-08 1996-12-05 Derives benzimidazole substitues par un naphtyle comme anticoagulants

Publications (1)

Publication Number Publication Date
CA2239508A1 true CA2239508A1 (fr) 1997-06-19

Family

ID=29404432

Family Applications (1)

Application Number Title Priority Date Filing Date
CA 2239508 Abandoned CA2239508A1 (fr) 1995-12-08 1996-12-05 Derives benzimidazole substitues par un naphtyle comme anticoagulants

Country Status (1)

Country Link
CA (1) CA2239508A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007143825A1 (fr) * 2006-06-12 2007-12-21 Merck Frosst Canada Ltd. Dérivés amide de l'indoline en tant que ligands du récepteur ep4

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007143825A1 (fr) * 2006-06-12 2007-12-21 Merck Frosst Canada Ltd. Dérivés amide de l'indoline en tant que ligands du récepteur ep4
US7705035B2 (en) 2006-06-12 2010-04-27 Merck Frosst Canada Ltd. Indoline amide derivatives as EP4 receptor ligands
AU2007260529B2 (en) * 2006-06-12 2012-04-19 Merck Canada Inc. Indoline amide derivatives as EP4 receptor ligands

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Legal Events

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EEER Examination request
FZDE Dead