CA2239296A1 - Glyconconjugues comme inhibiteurs d'adherence cellulaire virale - Google Patents
Glyconconjugues comme inhibiteurs d'adherence cellulaire virale Download PDFInfo
- Publication number
- CA2239296A1 CA2239296A1 CA 2239296 CA2239296A CA2239296A1 CA 2239296 A1 CA2239296 A1 CA 2239296A1 CA 2239296 CA2239296 CA 2239296 CA 2239296 A CA2239296 A CA 2239296A CA 2239296 A1 CA2239296 A1 CA 2239296A1
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- CA
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- Prior art keywords
- compounds
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- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Saccharide Compounds (AREA)
Abstract
L'adhérence de virus humains de la grippe à des cellules hôte est inhibée par de nouveaux composés de la formule générale (1), où R?1¿ représente un acyle ou un groupe thioacyle; R?2¿ représente hydroxyle, Z-alkyle, Z-alkyle substitué, Z-aryle, Z-aryle substitué et où Z correspond à O, S ou NH; R?3¿ représente un acyle ou un groupe thioacyle; R?4¿ représente H ou acyl; X représente O, S, SH¿2? ou un sucre; W est un espaceur bifonctionnel; P est un vecteur multivalent constitué de l'une des substances suivantes: polyacrylate, polyacrylamide, polyacrylamide substitué en N, métacrylamide, métalcrylamide substitué en N, acide polyacryle, polycarbonate, polyester, polyamide, polyanhydride, polyiminocarbonate, polyorthoester, polydioxanone, polyphosphazène, acide carboxylique polyhydroxy, acide polyaminé, polysaccharide, protéine, dextrane, chitosane, glucane, liposome, microparticules. Les nouveaux composés en question ont la propriété de lier d'authentiques virus humains des groupes A (H1 et H3) et B, non adaptés par culture dans des oeufs de poules.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19640791.5 | 1996-10-02 | ||
DE19640791A DE19640791A1 (de) | 1996-10-02 | 1996-10-02 | Glycokonjugate als Inhibitoren der viralen Zelladhäsion |
PCT/EP1997/005389 WO1998014215A2 (fr) | 1996-10-02 | 1997-10-01 | Glyconconjugues comme inhibiteurs d'adherence cellulaire virale |
Publications (1)
Publication Number | Publication Date |
---|---|
CA2239296A1 true CA2239296A1 (fr) | 1998-04-09 |
Family
ID=29403686
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA 2239296 Abandoned CA2239296A1 (fr) | 1996-10-02 | 1997-10-01 | Glyconconjugues comme inhibiteurs d'adherence cellulaire virale |
Country Status (1)
Country | Link |
---|---|
CA (1) | CA2239296A1 (fr) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20100168366A1 (en) * | 2007-06-28 | 2010-07-01 | Shizuoka Prefectural Universities Corporation | Novel synthetic n-linked sialo-glycan-containing polymer and method for producing the same |
-
1997
- 1997-10-01 CA CA 2239296 patent/CA2239296A1/fr not_active Abandoned
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20100168366A1 (en) * | 2007-06-28 | 2010-07-01 | Shizuoka Prefectural Universities Corporation | Novel synthetic n-linked sialo-glycan-containing polymer and method for producing the same |
US8450441B2 (en) | 2007-06-28 | 2013-05-28 | National University Corporation Shizuoka University | Synthetic N-linked sialo-glycan-containing polymer and method for producing the same |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FZDE | Dead |