CA2236199A1 - High pressure ms/ms system - Google Patents

High pressure ms/ms system Download PDF

Info

Publication number
CA2236199A1
CA2236199A1 CA 2236199 CA2236199A CA2236199A1 CA 2236199 A1 CA2236199 A1 CA 2236199A1 CA 2236199 CA2236199 CA 2236199 CA 2236199 A CA2236199 A CA 2236199A CA 2236199 A1 CA2236199 A1 CA 2236199A1
Authority
CA
Canada
Prior art keywords
high pressure
fnf
quadrupole
swift
mass
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA 2236199
Other languages
French (fr)
Other versions
CA2236199C (en
Inventor
Gholamreza Javahery
Charles Jolliffe
Bruce Thomson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
DH Technologies Development Pte Ltd
Original Assignee
MDS Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by MDS Inc filed Critical MDS Inc
Priority to CA 2236199 priority Critical patent/CA2236199C/en
Publication of CA2236199A1 publication Critical patent/CA2236199A1/en
Application granted granted Critical
Publication of CA2236199C publication Critical patent/CA2236199C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/004—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/26—Mass spectrometers or separator tubes
    • H01J49/34—Dynamic spectrometers
    • H01J49/42—Stability-of-path spectrometers, e.g. monopole, quadrupole, multipole, farvitrons
    • H01J49/4205—Device types
    • H01J49/421—Mass filters, i.e. deviating unwanted ions without trapping
    • H01J49/4215—Quadrupole mass filters

Abstract

A mass spectrometer system in which ions are mass selected in an RF-only quadrupole at relatively high pressure (1 to 7 torr) using FNF or SWIFT, and are then fragmented in a following collision cell which is in the same vacuum chamber, thus reducing pumping needs.
The fragments can be mass analyzed in any desired way, including by another RF-only quadrupole in the same vacuum chamber and also using FNF or SWIFT. Triple MS can be performed in the same way.
CA 2236199 1998-04-28 1998-04-28 High pressure ms/ms system Expired - Fee Related CA2236199C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA 2236199 CA2236199C (en) 1998-04-28 1998-04-28 High pressure ms/ms system

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CA 2236199 CA2236199C (en) 1998-04-28 1998-04-28 High pressure ms/ms system

Publications (2)

Publication Number Publication Date
CA2236199A1 true CA2236199A1 (en) 1999-10-28
CA2236199C CA2236199C (en) 2006-10-03

Family

ID=29275620

Family Applications (1)

Application Number Title Priority Date Filing Date
CA 2236199 Expired - Fee Related CA2236199C (en) 1998-04-28 1998-04-28 High pressure ms/ms system

Country Status (1)

Country Link
CA (1) CA2236199C (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6992285B1 (en) 1999-06-10 2006-01-31 Mds Inc. Method and apparatus for analyzing a substance using MSn analysis
WO2010109288A1 (en) * 2009-03-20 2010-09-30 Dh Technologies Development Pte. Ltd. Method of processing multiple precursor ions in a tandem mass spectrometer

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6992285B1 (en) 1999-06-10 2006-01-31 Mds Inc. Method and apparatus for analyzing a substance using MSn analysis
WO2010109288A1 (en) * 2009-03-20 2010-09-30 Dh Technologies Development Pte. Ltd. Method of processing multiple precursor ions in a tandem mass spectrometer

Also Published As

Publication number Publication date
CA2236199C (en) 2006-10-03

Similar Documents

Publication Publication Date Title
WO1999040610A3 (en) A tandem time-of-flight mass spectrometer with delayed extraction and method for use
CA2364158A1 (en) Mass spectrometers and methods of mass spectrometry
CA2292487A1 (en) Bandpass reactive collision cell
CA2206667A1 (en) Plasma mass spectrometer
CA2327135A1 (en) Mass spectrometer system including a double ion guide interface and method of operation
CA2090217A1 (en) Method for increased resolution in tandem mass spectrometry
CA2333031A1 (en) Atmospheric pressure matrix assisted laser desorption
CA2350041A1 (en) Methods and apparatus for mass spectrometry
EP2056334A3 (en) Collision cell for mass spectrometer
CA2332534A1 (en) Mass spectrometry with multipole ion guides
CA2255122A1 (en) Improvements in ms/ms methods for a quadrupole/time of flight tandem mass spectrometer
WO2002044685A3 (en) Method for improving signal-to-noise ratios for atmospheric pressure ionization mass spectrometry
AU4059597A (en) Ion storage time-of-flight mass spectrometer
AU4149797A (en) Multipole ion guide ion trap mass spectrometry
CA2355552A1 (en) Mass spectrometers and methods of mass spectrometry
WO2002048699A3 (en) Apparatus and method for msnth in a tandem mass spectrometer system
AU1932095A (en) Multipole ion guide for mass spectrometry
AU2334199A (en) Mass spectrometry with multipole ion guide
EP1493173B8 (en) Fragmentation of ions by resonant excitation in a high order multipole field, low pressure ion trap
CA2676411A1 (en) Means for removing unwanted ions from an ion transport system and mass spectrometer
GB9928729D0 (en) Daughter ion spectra with time-of-flight mass spectrometers
WO2001031683A8 (en) Plasma doping system comprising a hollow cathode
CA2373351A1 (en) Ion mobility and mass spectrometer
WO2005022583A3 (en) Reduction of matrix interference for maldi mass spectrometry analysis
AU3668599A (en) Ion trap mass spectrometer with electrospray ionization

Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed

Effective date: 20130429