CA2234607A1 - Animal feed additives - Google Patents
Animal feed additives Download PDFInfo
- Publication number
- CA2234607A1 CA2234607A1 CA002234607A CA2234607A CA2234607A1 CA 2234607 A1 CA2234607 A1 CA 2234607A1 CA 002234607 A CA002234607 A CA 002234607A CA 2234607 A CA2234607 A CA 2234607A CA 2234607 A1 CA2234607 A1 CA 2234607A1
- Authority
- CA
- Canada
- Prior art keywords
- animal feed
- galactosidase
- beta
- galactanase
- enzyme
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 235000019730 animal feed additive Nutrition 0.000 title claims abstract description 17
- 102000004190 Enzymes Human genes 0.000 claims abstract description 63
- 108090000790 Enzymes Proteins 0.000 claims abstract description 63
- SATHPVQTSSUFFW-UHFFFAOYSA-N 4-[6-[(3,5-dihydroxy-4-methoxyoxan-2-yl)oxymethyl]-3,5-dihydroxy-4-methoxyoxan-2-yl]oxy-2-(hydroxymethyl)-6-methyloxane-3,5-diol Chemical compound OC1C(OC)C(O)COC1OCC1C(O)C(OC)C(O)C(OC2C(C(CO)OC(C)C2O)O)O1 SATHPVQTSSUFFW-UHFFFAOYSA-N 0.000 claims abstract description 12
- 229920000189 Arabinogalactan Polymers 0.000 claims abstract description 12
- 239000001904 Arabinogalactan Substances 0.000 claims abstract description 12
- 235000019312 arabinogalactan Nutrition 0.000 claims abstract description 12
- 229940088598 enzyme Drugs 0.000 claims description 60
- 241001465754 Metazoa Species 0.000 claims description 27
- 238000000034 method Methods 0.000 claims description 26
- 108010059881 Lactase Proteins 0.000 claims description 17
- 108010005774 beta-Galactosidase Proteins 0.000 claims description 17
- 102100026189 Beta-galactosidase Human genes 0.000 claims description 16
- 229940116108 lactase Drugs 0.000 claims description 16
- 108010011619 6-Phytase Proteins 0.000 claims description 14
- 239000000203 mixture Substances 0.000 claims description 10
- -1 .beta.-glucanase Proteins 0.000 claims description 8
- 101710121765 Endo-1,4-beta-xylanase Proteins 0.000 claims description 7
- 239000000654 additive Substances 0.000 claims description 6
- 230000000996 additive effect Effects 0.000 claims description 6
- 229940085127 phytase Drugs 0.000 claims description 6
- 239000007788 liquid Substances 0.000 claims description 5
- 238000011282 treatment Methods 0.000 claims description 5
- UHZZMRAGKVHANO-UHFFFAOYSA-M chlormequat chloride Chemical compound [Cl-].C[N+](C)(C)CCCl UHZZMRAGKVHANO-UHFFFAOYSA-M 0.000 claims description 4
- 238000002203 pretreatment Methods 0.000 claims description 3
- 239000006053 animal diet Substances 0.000 claims description 2
- 230000009469 supplementation Effects 0.000 claims description 2
- 108020004511 Recombinant DNA Proteins 0.000 claims 1
- 101710152845 Arabinogalactan endo-beta-1,4-galactanase Proteins 0.000 abstract description 29
- 101710147028 Endo-beta-1,4-galactanase Proteins 0.000 abstract description 29
- 235000005911 diet Nutrition 0.000 description 11
- 239000003674 animal food additive Substances 0.000 description 10
- 230000037213 diet Effects 0.000 description 10
- 238000002474 experimental method Methods 0.000 description 10
- 210000003608 fece Anatomy 0.000 description 10
- 230000002708 enhancing effect Effects 0.000 description 9
- 241000228212 Aspergillus Species 0.000 description 7
- 150000004676 glycans Chemical class 0.000 description 7
- 239000000047 product Substances 0.000 description 7
- 241000287828 Gallus gallus Species 0.000 description 6
- 235000014590 basal diet Nutrition 0.000 description 6
- 229930182830 galactose Natural products 0.000 description 6
- 239000005017 polysaccharide Substances 0.000 description 6
- 238000002360 preparation method Methods 0.000 description 6
- 241000271566 Aves Species 0.000 description 5
- 241000193830 Bacillus <bacterium> Species 0.000 description 5
- 241000233866 Fungi Species 0.000 description 5
- 108010093031 Galactosidases Proteins 0.000 description 5
- 102000002464 Galactosidases Human genes 0.000 description 5
- 230000015556 catabolic process Effects 0.000 description 5
- 235000013339 cereals Nutrition 0.000 description 5
- 238000006731 degradation reaction Methods 0.000 description 5
- 239000002609 medium Substances 0.000 description 5
- 229920001282 polysaccharide Polymers 0.000 description 5
- 241000228215 Aspergillus aculeatus Species 0.000 description 4
- 241000228245 Aspergillus niger Species 0.000 description 4
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 4
- 241000223198 Humicola Species 0.000 description 4
- 240000004808 Saccharomyces cerevisiae Species 0.000 description 4
- 235000014680 Saccharomyces cerevisiae Nutrition 0.000 description 4
- 235000019621 digestibility Nutrition 0.000 description 4
- 244000144977 poultry Species 0.000 description 4
- 235000013594 poultry meat Nutrition 0.000 description 4
- 241000235349 Ascomycota Species 0.000 description 3
- 240000006439 Aspergillus oryzae Species 0.000 description 3
- 235000002247 Aspergillus oryzae Nutrition 0.000 description 3
- 108020004414 DNA Proteins 0.000 description 3
- 235000010469 Glycine max Nutrition 0.000 description 3
- 241000221775 Hypocreales Species 0.000 description 3
- 241000219745 Lupinus Species 0.000 description 3
- 241000226677 Myceliophthora Species 0.000 description 3
- 244000046052 Phaseolus vulgaris Species 0.000 description 3
- 235000010627 Phaseolus vulgaris Nutrition 0.000 description 3
- 241000235070 Saccharomyces Species 0.000 description 3
- 240000006394 Sorghum bicolor Species 0.000 description 3
- 235000011684 Sorghum saccharatum Nutrition 0.000 description 3
- 235000019764 Soybean Meal Nutrition 0.000 description 3
- 230000001580 bacterial effect Effects 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 230000002538 fungal effect Effects 0.000 description 3
- 239000004455 soybean meal Substances 0.000 description 3
- 241000228195 Aspergillus ficuum Species 0.000 description 2
- 244000063299 Bacillus subtilis Species 0.000 description 2
- 235000014469 Bacillus subtilis Nutrition 0.000 description 2
- 241000221198 Basidiomycota Species 0.000 description 2
- 241000219310 Beta vulgaris subsp. vulgaris Species 0.000 description 2
- 241001489107 Cantharellales Species 0.000 description 2
- 241000221785 Erysiphales Species 0.000 description 2
- 241000588724 Escherichia coli Species 0.000 description 2
- 244000068988 Glycine max Species 0.000 description 2
- 241001480714 Humicola insolens Species 0.000 description 2
- 241000123315 Meripilus Species 0.000 description 2
- 108091028043 Nucleic acid sequence Proteins 0.000 description 2
- 241000228143 Penicillium Species 0.000 description 2
- 108091005804 Peptidases Proteins 0.000 description 2
- 240000004713 Pisum sativum Species 0.000 description 2
- 235000010582 Pisum sativum Nutrition 0.000 description 2
- 241000222383 Polyporales Species 0.000 description 2
- 239000004365 Protease Substances 0.000 description 2
- 235000019779 Rapeseed Meal Nutrition 0.000 description 2
- 229920002472 Starch Polymers 0.000 description 2
- 235000021536 Sugar beet Nutrition 0.000 description 2
- 241000282887 Suidae Species 0.000 description 2
- 235000019772 Sunflower meal Nutrition 0.000 description 2
- 241000223257 Thermomyces Species 0.000 description 2
- 239000006227 byproduct Substances 0.000 description 2
- 210000004027 cell Anatomy 0.000 description 2
- 235000013330 chicken meat Nutrition 0.000 description 2
- 239000000539 dimer Substances 0.000 description 2
- 238000001035 drying Methods 0.000 description 2
- 235000021050 feed intake Nutrition 0.000 description 2
- 238000000855 fermentation Methods 0.000 description 2
- 230000004151 fermentation Effects 0.000 description 2
- 239000008187 granular material Substances 0.000 description 2
- 230000007062 hydrolysis Effects 0.000 description 2
- 238000006460 hydrolysis reaction Methods 0.000 description 2
- 238000002955 isolation Methods 0.000 description 2
- 235000012054 meals Nutrition 0.000 description 2
- 230000000813 microbial effect Effects 0.000 description 2
- 150000002772 monosaccharides Chemical class 0.000 description 2
- 229910052757 nitrogen Inorganic materials 0.000 description 2
- 239000013600 plasmid vector Substances 0.000 description 2
- 150000004804 polysaccharides Polymers 0.000 description 2
- 238000000746 purification Methods 0.000 description 2
- 239000004456 rapeseed meal Substances 0.000 description 2
- 150000003839 salts Chemical class 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- 239000008107 starch Substances 0.000 description 2
- GUBGYTABKSRVRQ-WWZHPTPQSA-N 4-O-β-D-Galactopyranosyl-D-galactopyranose Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@H]1[C@@H](CO)O[C@@H](O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-WWZHPTPQSA-N 0.000 description 1
- DEXFNLNNUZKHNO-UHFFFAOYSA-N 6-[3-[4-[2-(2,3-dihydro-1H-inden-2-ylamino)pyrimidin-5-yl]piperidin-1-yl]-3-oxopropyl]-3H-1,3-benzoxazol-2-one Chemical compound C1C(CC2=CC=CC=C12)NC1=NC=C(C=N1)C1CCN(CC1)C(CCC1=CC2=C(NC(O2)=O)C=C1)=O DEXFNLNNUZKHNO-UHFFFAOYSA-N 0.000 description 1
- 241000222485 Agaricales Species 0.000 description 1
- 241000222382 Agaricomycotina Species 0.000 description 1
- 241001513093 Aspergillus awamori Species 0.000 description 1
- 241000351920 Aspergillus nidulans Species 0.000 description 1
- 241001465318 Aspergillus terreus Species 0.000 description 1
- 241000221452 Auriculariales Species 0.000 description 1
- 241000194103 Bacillus pumilus Species 0.000 description 1
- 235000013277 Bacillus subtilis subsp amylosacchariticus Nutrition 0.000 description 1
- 244000055982 Bacillus subtilis subsp amylosacchariticus Species 0.000 description 1
- 240000002791 Brassica napus Species 0.000 description 1
- 235000004977 Brassica sinapistrum Nutrition 0.000 description 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 1
- 108010059892 Cellulase Proteins 0.000 description 1
- 108010084185 Cellulases Proteins 0.000 description 1
- 102000005575 Cellulases Human genes 0.000 description 1
- 241001494491 Chaetomiaceae Species 0.000 description 1
- 241001138366 Dacrymycetales Species 0.000 description 1
- 241000863390 Dictyoglomus Species 0.000 description 1
- 108010082495 Dietary Plant Proteins Proteins 0.000 description 1
- 241000228427 Eurotiales Species 0.000 description 1
- 241000193385 Geobacillus stearothermophilus Species 0.000 description 1
- 244000061944 Helianthus giganteus Species 0.000 description 1
- 238000011993 High Performance Size Exclusion Chromatography Methods 0.000 description 1
- 240000005979 Hordeum vulgare Species 0.000 description 1
- 235000007340 Hordeum vulgare Nutrition 0.000 description 1
- 108090000604 Hydrolases Proteins 0.000 description 1
- 102000004157 Hydrolases Human genes 0.000 description 1
- 241000123318 Meripilus giganteus Species 0.000 description 1
- 241000221960 Neurospora Species 0.000 description 1
- 241001465194 Onygenales Species 0.000 description 1
- 240000007594 Oryza sativa Species 0.000 description 1
- 235000007164 Oryza sativa Nutrition 0.000 description 1
- 102000035195 Peptidases Human genes 0.000 description 1
- 241000286209 Phasianidae Species 0.000 description 1
- 241000222341 Polyporaceae Species 0.000 description 1
- 241000589516 Pseudomonas Species 0.000 description 1
- 102100037486 Reverse transcriptase/ribonuclease H Human genes 0.000 description 1
- 241000235527 Rhizopus Species 0.000 description 1
- 241000235342 Saccharomycetes Species 0.000 description 1
- 241001292348 Salipaludibacillus agaradhaerens Species 0.000 description 1
- 241000209056 Secale Species 0.000 description 1
- 235000007238 Secale cereale Nutrition 0.000 description 1
- 241000221926 Sordariales Species 0.000 description 1
- 241000187747 Streptomyces Species 0.000 description 1
- 241000223258 Thermomyces lanuginosus Species 0.000 description 1
- 241000204652 Thermotoga Species 0.000 description 1
- 241001136486 Trichocomaceae Species 0.000 description 1
- 241000223259 Trichoderma Species 0.000 description 1
- 235000021307 Triticum Nutrition 0.000 description 1
- 244000098338 Triticum aestivum Species 0.000 description 1
- 240000008042 Zea mays Species 0.000 description 1
- 235000016383 Zea mays subsp huehuetenangensis Nutrition 0.000 description 1
- 235000002017 Zea mays subsp mays Nutrition 0.000 description 1
- 238000001042 affinity chromatography Methods 0.000 description 1
- BFNBIHQBYMNNAN-UHFFFAOYSA-N ammonium sulfate Chemical compound N.N.OS(O)(=O)=O BFNBIHQBYMNNAN-UHFFFAOYSA-N 0.000 description 1
- 229910052921 ammonium sulfate Inorganic materials 0.000 description 1
- 239000001166 ammonium sulphate Substances 0.000 description 1
- 235000011130 ammonium sulphate Nutrition 0.000 description 1
- 238000003556 assay Methods 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000027455 binding Effects 0.000 description 1
- 238000009739 binding Methods 0.000 description 1
- 238000004166 bioassay Methods 0.000 description 1
- 244000309466 calf Species 0.000 description 1
- 150000001720 carbohydrates Chemical class 0.000 description 1
- 235000014633 carbohydrates Nutrition 0.000 description 1
- 229910052799 carbon Inorganic materials 0.000 description 1
- 239000000969 carrier Substances 0.000 description 1
- 229940106157 cellulase Drugs 0.000 description 1
- 238000005119 centrifugation Methods 0.000 description 1
- 238000004587 chromatography analysis Methods 0.000 description 1
- 210000000349 chromosome Anatomy 0.000 description 1
- 239000000470 constituent Substances 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 238000012258 culturing Methods 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 239000007857 degradation product Substances 0.000 description 1
- 230000000378 dietary effect Effects 0.000 description 1
- 230000029087 digestion Effects 0.000 description 1
- 102000038379 digestive enzymes Human genes 0.000 description 1
- 108091007734 digestive enzymes Proteins 0.000 description 1
- 229940079919 digestives enzyme preparation Drugs 0.000 description 1
- 238000004821 distillation Methods 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 239000012634 fragment Substances 0.000 description 1
- 210000001035 gastrointestinal tract Anatomy 0.000 description 1
- 238000001641 gel filtration chromatography Methods 0.000 description 1
- 239000001963 growth medium Substances 0.000 description 1
- 238000010348 incorporation Methods 0.000 description 1
- 238000011534 incubation Methods 0.000 description 1
- 238000004255 ion exchange chromatography Methods 0.000 description 1
- 235000009973 maize Nutrition 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000011159 matrix material Substances 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 230000000050 nutritive effect Effects 0.000 description 1
- 229920001542 oligosaccharide Polymers 0.000 description 1
- 150000002482 oligosaccharides Chemical class 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 229920001277 pectin Polymers 0.000 description 1
- 239000001814 pectin Substances 0.000 description 1
- 235000010987 pectin Nutrition 0.000 description 1
- 239000000546 pharmaceutical excipient Substances 0.000 description 1
- 239000013612 plasmid Substances 0.000 description 1
- 229920000642 polymer Polymers 0.000 description 1
- 230000001376 precipitating effect Effects 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 230000003362 replicative effect Effects 0.000 description 1
- 235000009566 rice Nutrition 0.000 description 1
- 239000002002 slurry Substances 0.000 description 1
- 210000000813 small intestine Anatomy 0.000 description 1
- 239000007974 sodium acetate buffer Substances 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 239000007858 starting material Substances 0.000 description 1
- 238000004448 titration Methods 0.000 description 1
- 238000000108 ultra-filtration Methods 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
- C12Y302/01089—Arabinogalactan endo-beta-1,4-galactanase (3.2.1.89)
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/189—Enzymes
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K10/00—Animal feeding-stuffs
- A23K10/10—Animal feeding-stuffs obtained by microbiological or biochemical processes
- A23K10/14—Pretreatment of feeding-stuffs with enzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
- C12Y302/01055—Alpha-N-arabinofuranosidase (3.2.1.55)
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Polymers & Plastics (AREA)
- Biochemistry (AREA)
- Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Microbiology (AREA)
- Animal Husbandry (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Food Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Physiology (AREA)
- Biomedical Technology (AREA)
- Fodder In General (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Feed For Specific Animals (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DK1233/95 | 1995-11-06 | ||
| DK123395 | 1995-11-06 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2234607A1 true CA2234607A1 (en) | 1997-05-15 |
Family
ID=8102499
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002234607A Abandoned CA2234607A1 (en) | 1995-11-06 | 1996-10-22 | Animal feed additives |
Country Status (13)
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000047711A2 (en) * | 1999-02-11 | 2000-08-17 | Novozymes A/S | Bacterial galactanases and use thereof |
| US6960462B2 (en) * | 2000-02-08 | 2005-11-01 | Dsm Ip Assets B.V | Use of acid-stable subtilisin proteases in animal feed |
| US6855548B2 (en) * | 2000-02-08 | 2005-02-15 | F. Hoffman-La Roche Ag | Use of acid-stable proteases in animal feed |
| US7566556B2 (en) * | 2002-03-01 | 2009-07-28 | Academia Sinica | Enhancing enzyme thermostability by mixing with sorghum liquor waste |
| AU2003298577A1 (en) * | 2002-09-10 | 2004-05-04 | Genencor International, Inc. | Induction of gene expression using a high concentration sugar mixture |
| EP1578963B1 (en) | 2002-12-20 | 2015-02-25 | Novozymes A/S | Galactanase variants |
| DK1973561T3 (da) * | 2005-12-15 | 2011-05-23 | Chemgen Corp | Enzymer til reducering af immunologisk stress |
| DK2254591T3 (da) * | 2008-02-08 | 2017-11-06 | Prothera Inc | Inhibering eller behandling af gastrointestinal biofilm |
| CN105231024B (zh) * | 2015-09-15 | 2016-12-07 | 上海国龙生物科技有限公司 | 一种用于饲料的复合酶制剂 |
| BR112018073283A2 (pt) * | 2016-05-24 | 2019-03-19 | Novozymes A/S | composição, grânulo, aditivo de ração para animal, ração para animal, ração para animal peletizada, formulação líquida, método para liberar galactose do material à base de planta, método para melhorar um ou mais parâmetros de desempenho de um animal, uso da composição, do grânulo, do aditivo de ração para animal ou da formulação líquida, polipeptídeo isolado, método para produzir o polipeptídeo, polinucleotídeo, construto de ácido nucleico ou vetor de expressão, e, célula hospedeira |
| US10947520B2 (en) | 2016-05-24 | 2021-03-16 | Novozymes A/S | Compositions comprising polypeptides having galactanase activity and polypeptides having beta-galactosidase activity |
| WO2019096903A1 (en) * | 2017-11-20 | 2019-05-23 | Novozymes A/S | New galactanases (ec 3.2.1.89) for use in soy processing |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0321481B1 (en) * | 1986-08-28 | 1994-06-01 | Enzacor Properties Limited | Microgranular preparation useful in the delivery of biologically active materials to the intestinal regions of animals |
| EP0498137A1 (en) * | 1991-02-06 | 1992-08-12 | Novo Nordisk A/S | Novel expression systems |
| WO1994014952A1 (en) * | 1992-12-23 | 1994-07-07 | Novo Nordisk A/S | An enzyme with polygalacturonase activity |
-
1996
- 1996-10-22 BR BR9611347A patent/BR9611347A/pt not_active Application Discontinuation
- 1996-10-22 AU AU72797/96A patent/AU714602B2/en not_active Ceased
- 1996-10-22 AT AT96934447T patent/ATE217153T1/de not_active IP Right Cessation
- 1996-10-22 CN CN96198103A patent/CN1201373A/zh active Pending
- 1996-10-22 ES ES96934447T patent/ES2175135T3/es not_active Expired - Lifetime
- 1996-10-22 WO PCT/DK1996/000443 patent/WO1997016982A1/en not_active Application Discontinuation
- 1996-10-22 CA CA002234607A patent/CA2234607A1/en not_active Abandoned
- 1996-10-22 EP EP96934447A patent/EP0862371B1/en not_active Expired - Lifetime
- 1996-10-22 JP JP9517759A patent/JPH11514528A/ja active Pending
- 1996-10-22 DE DE69621146T patent/DE69621146T2/de not_active Expired - Lifetime
- 1996-10-22 KR KR1019980703361A patent/KR19990067354A/ko not_active Ceased
- 1996-10-28 IN IN1893MA1996 patent/IN183952B/en unknown
-
1998
- 1998-04-14 US US09/059,771 patent/US6558693B1/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JPH11514528A (ja) | 1999-12-14 |
| KR19990067354A (ko) | 1999-08-16 |
| AU714602B2 (en) | 2000-01-06 |
| EP0862371A1 (en) | 1998-09-09 |
| US6558693B1 (en) | 2003-05-06 |
| ATE217153T1 (de) | 2002-05-15 |
| ES2175135T3 (es) | 2002-11-16 |
| EP0862371B1 (en) | 2002-05-08 |
| WO1997016982A1 (en) | 1997-05-15 |
| CN1201373A (zh) | 1998-12-09 |
| MX9803507A (es) | 1998-09-30 |
| DE69621146T2 (de) | 2002-11-28 |
| AU7279796A (en) | 1997-05-29 |
| IN183952B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 2000-05-20 |
| BR9611347A (pt) | 1999-03-09 |
| DE69621146D1 (de) | 2002-06-13 |
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Effective date: 20031022 |