CA2232411A1 - (radio) labelled biotin derivatives - Google Patents

(radio) labelled biotin derivatives Download PDF

Info

Publication number
CA2232411A1
CA2232411A1 CA002232411A CA2232411A CA2232411A1 CA 2232411 A1 CA2232411 A1 CA 2232411A1 CA 002232411 A CA002232411 A CA 002232411A CA 2232411 A CA2232411 A CA 2232411A CA 2232411 A1 CA2232411 A1 CA 2232411A1
Authority
CA
Canada
Prior art keywords
group
composition
compound
labelled
tumour
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002232411A
Other languages
English (en)
French (fr)
Inventor
Helmut Macke
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mallinckrodt Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2232411A1 publication Critical patent/CA2232411A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/085—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier conjugated systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0497—Organic compounds conjugates with a carrier being an organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00—Preparations for use in therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00—Preparations for testing in vivo

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Radiology & Medical Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CA002232411A 1995-09-18 1996-09-17 (radio) labelled biotin derivatives Abandoned CA2232411A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP95202512.0 1995-09-18
EP95202512 1995-09-18

Publications (1)

Publication Number Publication Date
CA2232411A1 true CA2232411A1 (en) 1997-03-27

Family

ID=8220642

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002232411A Abandoned CA2232411A1 (en) 1995-09-18 1996-09-17 (radio) labelled biotin derivatives

Country Status (7)

Country Link
EP (1) EP0857071A1 (de)
JP (1) JPH11513374A (de)
CA (1) CA2232411A1 (de)
CZ (1) CZ75498A3 (de)
IL (1) IL123725A0 (de)
NO (1) NO981202L (de)
WO (1) WO1997010854A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU699216B2 (en) * 1995-06-07 1998-11-26 Immunomedics Inc. Improved delivery of diagnostic and therapeutic agents to a target site
CA2373993C (en) * 1999-05-25 2008-11-18 Barnes-Jewish Hospital Site specific binding system, nuclear imaging compositions and methods
US7371579B1 (en) * 1999-07-01 2008-05-13 The University Of Maryland Nickel-based reagents for detecting DNA and DNA-protein contacts
ITRM20010079A1 (it) * 2001-02-16 2002-08-16 Sigma Tau Ind Farmaceuti Amminoderivati della biotina e loro coniugati con chelanti macrociclici.
GB0416062D0 (en) * 2004-07-19 2004-08-18 Amersham Plc Improved N4 chelator conjugates
CN101932722A (zh) * 2007-12-05 2010-12-29 伦敦王室学院 方法和组合物
CN102336908B (zh) * 2010-07-20 2013-07-03 中国科学院上海应用物理研究所 一种99mTc配合物、其制备方法、中间体及其应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5541287A (en) * 1992-06-09 1996-07-30 Neorx Corporation Pretargeting methods and compounds

Also Published As

Publication number Publication date
IL123725A0 (en) 1998-12-06
NO981202D0 (no) 1998-03-17
JPH11513374A (ja) 1999-11-16
CZ75498A3 (cs) 1999-09-15
WO1997010854A1 (en) 1997-03-27
MX9802107A (es) 1998-08-30
EP0857071A1 (de) 1998-08-12
NO981202L (no) 1998-05-18

Similar Documents

Publication Publication Date Title
US6056939A (en) Self-assembling heteropolymetallic chelates as imaging agents and radiopharmaceuticals
IE892045L (en) Macrocyclic bifunctional chelants, complexes thereof and¹their antibody conjugates
AU728712B2 (en) Method for the detection and localization of malignant human tumours
JPH0881498A (ja) ペプチド類
US8044081B2 (en) Aminoderivative of biotin and their conjugates with macrocyclic chelating agents
CA2232411A1 (en) (radio) labelled biotin derivatives
AU2006298827B2 (en) Biotin diaminoderivatives and their conjugates with macrocyclic chelating agents
AU2002237517A1 (en) Biotin-derivatives and their conjugates with chelating agents
WO2000059896A1 (en) 225Ac-HEHA AND RELATED COMPOUNDS, METHODS OF SYNTHESIS AND METHODS OF USE
US20040185510A1 (en) Use of labelled CCK-B receptor ligands for the detection and localization of malignant human tumours
MXPA98002107A (en) Biotin derivatives marked radiactivame
EP0783326B1 (de) Verfahren zur herstellung von makrozyklischen agentien und ihren chelaten und konjugaten
CA2436242C (en) Biotin-derivatives and their conjugates with chelating agents
HU221187B1 (en) Process for the production of 1,4,7,10-tetraazacyclododecane derivatives, complexes and conjugates with antibody thereof and medicaments containing the same and diagnostics compraising these conjugates and complexes
CZ279099A3 (cs) Způsob detekce a lokalizaci lidských maligních tumorů

Legal Events

Date Code Title Description
FZDE Discontinued
FZDE Discontinued

Effective date: 20030917