CA2228393A1 - Use of adamantane derivatives for treating diseases of the inner ear - Google Patents
Use of adamantane derivatives for treating diseases of the inner earInfo
- Publication number
- CA2228393A1 CA2228393A1 CA002228393A CA2228393A CA2228393A1 CA 2228393 A1 CA2228393 A1 CA 2228393A1 CA 002228393 A CA002228393 A CA 002228393A CA 2228393 A CA2228393 A CA 2228393A CA 2228393 A1 CA2228393 A1 CA 2228393A1
- Authority
- CA
- Canada
- Prior art keywords
- carbon atoms
- treating diseases
- inner ear
- adamantane derivatives
- chained
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- ORILYTVJVMAKLC-UHFFFAOYSA-N adamantane Chemical class C1C(C2)CC3CC1CC2C3 ORILYTVJVMAKLC-UHFFFAOYSA-N 0.000 title abstract 2
- 201000010099 disease Diseases 0.000 title abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title abstract 2
- 229940052761 dopaminergic adamantane derivative Drugs 0.000 title abstract 2
- 210000003027 ear inner Anatomy 0.000 title abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 4
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 150000002431 hydrogen Chemical class 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 125000006413 ring segment Chemical group 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Use of adamantane derivatives of the formula (see formula I) in which R1 and R2 - are identical or different and can be hydrogen or straight-chained or branched alkyl groups having 1 to 6 carbon atoms, or - together with the nitrogen atom can represent a heterocyclic group having 5 or 6 ring atoms, in which R3 and R4 are identical or different and can be hydrogen, straight-chained or branched alkyl groups having between 1 and 6 carbon atoms, cycloalkyl groups having 5 or 6 carbon atoms or a phenyl group, and in which R5 is hydrogen or a straight-chained or branched alkyl group having between 1 and 6 carbon atoms for treating diseases of the inner ear.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19528388.0 | 1995-08-02 | ||
| DE19528388A DE19528388A1 (en) | 1995-08-02 | 1995-08-02 | Use of adamantane derivatives for the treatment of diseases of the inner ear |
| PCT/EP1996/003360 WO1997004762A1 (en) | 1995-08-02 | 1996-07-31 | Use of adamantane derivatives for treating diseases of the inner ear |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2228393A1 true CA2228393A1 (en) | 1997-02-13 |
| CA2228393C CA2228393C (en) | 2006-10-10 |
Family
ID=37112521
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002228393A Expired - Fee Related CA2228393C (en) | 1995-08-02 | 1996-07-31 | Use of adamantane derivatives for treating diseases of the inner ear |
Country Status (1)
| Country | Link |
|---|---|
| CA (1) | CA2228393C (en) |
-
1996
- 1996-07-31 CA CA002228393A patent/CA2228393C/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CA2228393C (en) | 2006-10-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| MKLA | Lapsed |
Effective date: 20140731 |