CA2226267C - Device and method for oral delivery of an active agent formulation in the form of discrete units - Google Patents
Device and method for oral delivery of an active agent formulation in the form of discrete units Download PDFInfo
- Publication number
- CA2226267C CA2226267C CA002226267A CA2226267A CA2226267C CA 2226267 C CA2226267 C CA 2226267C CA 002226267 A CA002226267 A CA 002226267A CA 2226267 A CA2226267 A CA 2226267A CA 2226267 C CA2226267 C CA 2226267C
- Authority
- CA
- Canada
- Prior art keywords
- active agent
- chamber
- agent formulation
- delivery system
- discrete units
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000013543 active substance Substances 0.000 title claims abstract description 110
- 239000000203 mixture Substances 0.000 title claims abstract description 83
- 238000009472 formulation Methods 0.000 title claims abstract description 81
- 238000000034 method Methods 0.000 title abstract description 9
- 239000012530 fluid Substances 0.000 claims abstract description 54
- -1 anepileptics Substances 0.000 claims description 12
- 239000006186 oral dosage form Substances 0.000 claims description 9
- 230000003204 osmotic effect Effects 0.000 claims description 9
- 229940035676 analgesics Drugs 0.000 claims description 4
- 239000000730 antalgic agent Substances 0.000 claims description 4
- 230000003111 delayed effect Effects 0.000 claims description 4
- 230000002035 prolonged effect Effects 0.000 claims description 4
- 239000003242 anti bacterial agent Substances 0.000 claims description 3
- 229940121363 anti-inflammatory agent Drugs 0.000 claims description 3
- 239000002260 anti-inflammatory agent Substances 0.000 claims description 3
- 229940088710 antibiotic agent Drugs 0.000 claims description 3
- 239000003443 antiviral agent Substances 0.000 claims description 2
- 229940124630 bronchodilator Drugs 0.000 claims description 2
- 239000000168 bronchodilator agent Substances 0.000 claims description 2
- 239000003814 drug Substances 0.000 description 21
- 239000007788 liquid Substances 0.000 description 17
- 239000010902 straw Substances 0.000 description 15
- 229940079593 drug Drugs 0.000 description 14
- 210000000214 mouth Anatomy 0.000 description 13
- 239000003795 chemical substances by application Substances 0.000 description 12
- 239000003826 tablet Substances 0.000 description 10
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- 230000002936 tranquilizing effect Effects 0.000 description 1
- 229960005294 triamcinolone Drugs 0.000 description 1
- GFNANZIMVAIWHM-OBYCQNJPSA-N triamcinolone Chemical compound O=C1C=C[C@]2(C)[C@@]3(F)[C@@H](O)C[C@](C)([C@@]([C@H](O)C4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 GFNANZIMVAIWHM-OBYCQNJPSA-N 0.000 description 1
- XJGONMZLEDGBRM-UHFFFAOYSA-M tridihexethyl chloride Chemical compound [Cl-].C=1C=CC=CC=1C(O)(CC[N+](CC)(CC)CC)C1CCCCC1 XJGONMZLEDGBRM-UHFFFAOYSA-M 0.000 description 1
- 229960001205 tridihexethyl chloride Drugs 0.000 description 1
- 229960003726 vasopressin Drugs 0.000 description 1
- 229960002726 vincamine Drugs 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 235000019154 vitamin C Nutrition 0.000 description 1
- 239000011718 vitamin C Substances 0.000 description 1
- ZXVNMYWKKDOREA-UHFFFAOYSA-N zomepirac Chemical compound C1=C(CC(O)=O)N(C)C(C(=O)C=2C=CC(Cl)=CC=2)=C1C ZXVNMYWKKDOREA-UHFFFAOYSA-N 0.000 description 1
- 229960003414 zomepirac Drugs 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A47—FURNITURE; DOMESTIC ARTICLES OR APPLIANCES; COFFEE MILLS; SPICE MILLS; SUCTION CLEANERS IN GENERAL
- A47G—HOUSEHOLD OR TABLE EQUIPMENT
- A47G21/00—Table-ware
- A47G21/18—Drinking straws or the like
- A47G21/183—Drinking straws or the like with means for changing the flavour of the liquid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J7/00—Devices for administering medicines orally, e.g. spoons; Pill counting devices; Arrangements for time indication or reminder for taking medicine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J7/00—Devices for administering medicines orally, e.g. spoons; Pill counting devices; Arrangements for time indication or reminder for taking medicine
- A61J7/0015—Devices specially adapted for taking medicines
- A61J7/0038—Straws
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Feeding, Discharge, Calcimining, Fusing, And Gas-Generation Devices (AREA)
- Vending Machines For Individual Products (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US131995P | 1995-07-21 | 1995-07-21 | |
| US60/001,319 | 1995-07-21 | ||
| US58254496A | 1996-01-03 | 1996-01-03 | |
| US08/582,544 | 1996-01-03 | ||
| PCT/US1996/011812 WO1997003634A1 (en) | 1995-07-21 | 1996-07-17 | Oral delivery of discrete units |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2226267A1 CA2226267A1 (en) | 1997-02-06 |
| CA2226267C true CA2226267C (en) | 2008-01-22 |
Family
ID=26668856
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002226267A Expired - Lifetime CA2226267C (en) | 1995-07-21 | 1996-07-17 | Device and method for oral delivery of an active agent formulation in the form of discrete units |
Country Status (16)
| Country | Link |
|---|---|
| EP (2) | EP0988850B1 (de) |
| JP (1) | JP3818664B2 (de) |
| KR (1) | KR100449538B1 (de) |
| CN (1) | CN1113640C (de) |
| AT (1) | ATE199638T1 (de) |
| AU (1) | AU713120B2 (de) |
| BR (1) | BR9609696A (de) |
| CA (1) | CA2226267C (de) |
| DE (1) | DE69612098T2 (de) |
| DK (2) | DK0840591T3 (de) |
| ES (2) | ES2228398T3 (de) |
| GR (1) | GR3035850T3 (de) |
| NZ (2) | NZ313010A (de) |
| PT (1) | PT840591E (de) |
| TW (1) | TW347339B (de) |
| WO (1) | WO1997003634A1 (de) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AUPS270602A0 (en) | 2002-05-31 | 2002-06-20 | Baron, Peter | Drink flavouring straw |
| US20030087005A1 (en) | 1996-10-10 | 2003-05-08 | Peter Baron | Drink flavouring straw |
| EP0942656B1 (de) * | 1996-10-10 | 2003-05-21 | Peter Baron | Vorrichtung zur herstellung eines aromatisierten getränkes |
| US6024721A (en) | 1996-10-18 | 2000-02-15 | Alza Corporation | Mixing system for an active agent delivery device |
| DK0936893T3 (da) * | 1996-10-18 | 2001-09-03 | Alza Corp | Indretning med flere strømningsbaner til oral afgivelse af diskrete enheder |
| AU729769B2 (en) * | 1996-10-18 | 2001-02-08 | Alza Corporation | Closure system for an active agent delivery device |
| WO1998034598A2 (en) * | 1997-02-07 | 1998-08-13 | Gist-Brocades B.V. | Homogeneous granulated formulations for dose sipping technology |
| WO1998041106A2 (en) | 1997-03-14 | 1998-09-24 | Unilever N.V. | Frozen food product containing anti-freeze peptides |
| ES2182303T3 (es) | 1997-05-16 | 2003-03-01 | Alza Corp | Configuraciones reguladoras del flujo para un dispositivo de administracion de agents activos. |
| US8052982B2 (en) | 1998-07-20 | 2011-11-08 | Peptech Animal Health Pty Limited | Bioimplant formulation comprising lecithin and stearin |
| RU2005138854A (ru) * | 2003-05-14 | 2006-07-27 | Куреха Корпорейшн (Jp) | Размещающий корпус для проглатывания твердой формы для перорального приема, контейнер для размещающего корпуса и способ проглатывания |
| DE10342513A1 (de) * | 2003-09-12 | 2005-05-12 | Gruenenthal Gmbh | Darreichungsform zur oralen Verabreichung von Wirkstoffen, Vitaminen und/oder Nährstoffen, Kit und Verwendung |
| DE10342514A1 (de) * | 2003-09-12 | 2005-04-07 | Grünenthal GmbH | Darreichungsform zur oralen Verabreichung von Wirkstoffen, Vitaminen und/oder Nährstoffen, Kit und Verwendung |
| US20060034886A1 (en) * | 2004-07-23 | 2006-02-16 | Ward Bennett C | Bonded fiber structures for use in controlling fluid flow |
| DE102005004257A1 (de) * | 2005-01-28 | 2006-08-24 | Grünenthal GmbH | Verfahren zur Herstellung eines Trinkhalms mit Controller |
| DE102005004256A1 (de) * | 2005-01-28 | 2006-08-10 | Grünenthal GmbH | Trinkhalm mit einer Versteifung |
| US20080312587A1 (en) * | 2005-06-10 | 2008-12-18 | Gruenethal Gmbh | System for the Oral Administration of Solids to Persons Suffering from Dementia |
| DE102005029289A1 (de) * | 2005-06-22 | 2006-12-28 | Grünenthal GmbH | Kappe für einen Trinkhalm mit einem zylindrischen Innendorn |
| AR060029A1 (es) | 2006-03-02 | 2008-05-21 | Unistraw Patent Holdings Ltd | Pajilla para beber adaptada para acondicionar progresivamente un ingrediente activo y metodo de fabricar dicha pajilla |
| AU2008210267B2 (en) | 2007-01-31 | 2014-06-12 | Sands Innovations Pty Ltd | A dispensing utensil and manufacturing method therefor |
| CA2683499A1 (en) | 2007-04-10 | 2008-10-16 | Sandoz Ag | Device for the oral application of a substance |
| EP2163242A1 (de) | 2008-09-10 | 2010-03-17 | Sandoz AG | Kapsel mit löslichem Blockierelement |
| EP2349222B1 (de) | 2008-09-10 | 2016-08-24 | Sandoz AG | Kapsel mit löslichem blockierelement |
| CN101537919B (zh) * | 2009-04-22 | 2014-02-19 | 广东润科生物工程有限公司 | 一种用于饮用固体物料的器具 |
| DE202011104802U1 (de) * | 2011-08-20 | 2012-01-26 | Christian Kober | Strohhalm zur Messung schädlicher Stoffe bzw. von Partydrogen in Getränken |
| US9017749B2 (en) | 2011-12-21 | 2015-04-28 | Babatope Sewande Ayeni | Flavored straw with a flavor delivery system |
| DE202012005997U1 (de) | 2012-06-20 | 2012-07-18 | Claus Linder | Gefäß für Getränke und Flüssigkeiten jeglicher Art zur Messung schädlicher Stoffe bzw. Rauschgift und Partydrogen in Getränken |
| US9005108B2 (en) * | 2012-09-27 | 2015-04-14 | Palo Alto Research Center Incorporated | Multiple reservoir drug delivery device and methods |
| GB201401516D0 (en) | 2014-01-29 | 2014-03-12 | Unistraw Holdings Pte Ltd | Drinking straw with piercing end |
| USD767931S1 (en) | 2013-09-12 | 2016-10-04 | Unistraw Holdings Pte. Ltd. | Beverage straw end with a beak |
| CN105030004B (zh) * | 2015-05-06 | 2017-01-04 | 曹杨 | 一种储物式吸管 |
| EP3932373B1 (de) | 2017-02-24 | 2022-12-21 | Bolton Medical, Inc. | Ausgabesystem zur radialen einschränkung eines stentimplantats |
| WO2021062987A1 (zh) * | 2019-09-30 | 2021-04-08 | 上海汉都医药科技有限公司 | 固体口服制剂的药物容置装置及含其的口服给药递送装置 |
| ZA202405911B (en) * | 2024-07-31 | 2025-04-30 | Brian Lesley Levy | A device to assist a user to ingest medication |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2436505A (en) * | 1945-08-24 | 1948-02-24 | Rall John H Du | Pill douser |
| US2867536A (en) * | 1954-05-07 | 1959-01-06 | Mead Bruce Ronald | Flavor-containing drinking straw |
| DE1906964A1 (de) * | 1969-02-07 | 1970-08-20 | Ernst Ruediger | Trinkhalm |
| US3610483A (en) * | 1969-12-01 | 1971-10-05 | Ralph Visconti | Dispenser with liquid-impervious vent |
| US4792333A (en) * | 1986-11-04 | 1988-12-20 | Strawdose, Inc. | Unit dose drug package and administering device |
| US4981468A (en) * | 1989-02-17 | 1991-01-01 | Eli Lilly And Company | Delivery device for orally administered therapeutic agents |
-
1996
- 1996-07-17 BR BR9609696A patent/BR9609696A/pt not_active IP Right Cessation
- 1996-07-17 DK DK96924555T patent/DK0840591T3/da active
- 1996-07-17 EP EP00200063A patent/EP0988850B1/de not_active Expired - Lifetime
- 1996-07-17 DE DE69612098T patent/DE69612098T2/de not_active Expired - Lifetime
- 1996-07-17 PT PT96924555T patent/PT840591E/pt unknown
- 1996-07-17 CA CA002226267A patent/CA2226267C/en not_active Expired - Lifetime
- 1996-07-17 EP EP96924555A patent/EP0840591B1/de not_active Expired - Lifetime
- 1996-07-17 CN CN96195726A patent/CN1113640C/zh not_active Expired - Lifetime
- 1996-07-17 AU AU64980/96A patent/AU713120B2/en not_active Expired
- 1996-07-17 ES ES00200063T patent/ES2228398T3/es not_active Expired - Lifetime
- 1996-07-17 KR KR1019970709987A patent/KR100449538B1/ko not_active Expired - Lifetime
- 1996-07-17 NZ NZ313010A patent/NZ313010A/xx not_active IP Right Cessation
- 1996-07-17 ES ES96924555T patent/ES2154829T3/es not_active Expired - Lifetime
- 1996-07-17 WO PCT/US1996/011812 patent/WO1997003634A1/en not_active Ceased
- 1996-07-17 AT AT96924555T patent/ATE199638T1/de active
- 1996-07-17 DK DK00200063T patent/DK0988850T3/da active
- 1996-07-17 JP JP50681697A patent/JP3818664B2/ja not_active Expired - Lifetime
- 1996-12-18 TW TW085115610A patent/TW347339B/zh not_active IP Right Cessation
-
1999
- 1999-02-01 NZ NZ333997A patent/NZ333997A/xx not_active IP Right Cessation
-
2001
- 2001-05-11 GR GR20010400700T patent/GR3035850T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| KR100449538B1 (ko) | 2004-12-17 |
| EP0988850A2 (de) | 2000-03-29 |
| CN1191476A (zh) | 1998-08-26 |
| JP3818664B2 (ja) | 2006-09-06 |
| JPH11510066A (ja) | 1999-09-07 |
| DK0840591T3 (da) | 2001-04-17 |
| DK0988850T3 (da) | 2005-01-24 |
| PT840591E (pt) | 2001-06-29 |
| DE69612098D1 (de) | 2001-04-19 |
| AU6498096A (en) | 1997-02-18 |
| AU713120B2 (en) | 1999-11-25 |
| WO1997003634A1 (en) | 1997-02-06 |
| EP0988850A3 (de) | 2000-05-17 |
| TW347339B (en) | 1998-12-11 |
| ES2154829T3 (es) | 2001-04-16 |
| BR9609696A (pt) | 1999-03-23 |
| HK1015671A1 (en) | 1999-10-22 |
| CN1113640C (zh) | 2003-07-09 |
| CA2226267A1 (en) | 1997-02-06 |
| NZ333997A (en) | 1999-03-29 |
| NZ313010A (en) | 1999-03-29 |
| ATE199638T1 (de) | 2001-03-15 |
| EP0988850B1 (de) | 2004-09-22 |
| DE69612098T2 (de) | 2001-06-21 |
| GR3035850T3 (en) | 2001-08-31 |
| KR19990028664A (ko) | 1999-04-15 |
| EP0840591A1 (de) | 1998-05-13 |
| EP0840591B1 (de) | 2001-03-14 |
| ES2228398T3 (es) | 2005-04-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| MKEX | Expiry |
Effective date: 20160718 |