CA2225824A1 - Genes et proteines specifiques au sein - Google Patents
Genes et proteines specifiques au sein Download PDFInfo
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- CA2225824A1 CA2225824A1 CA002225824A CA2225824A CA2225824A1 CA 2225824 A1 CA2225824 A1 CA 2225824A1 CA 002225824 A CA002225824 A CA 002225824A CA 2225824 A CA2225824 A CA 2225824A CA 2225824 A1 CA2225824 A1 CA 2225824A1
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- polypeptide
- dna
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- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
- LENZDBCJOHFCAS-UHFFFAOYSA-N tris Chemical compound OCC(N)(CO)CO LENZDBCJOHFCAS-UHFFFAOYSA-N 0.000 description 1
- 241000701366 unidentified nuclear polyhedrosis viruses Species 0.000 description 1
- 208000007089 vaccinia Diseases 0.000 description 1
- 238000012795 verification Methods 0.000 description 1
- 239000013603 viral vector Substances 0.000 description 1
- 239000011534 wash buffer Substances 0.000 description 1
- 238000001262 western blot Methods 0.000 description 1
- 210000005253 yeast cell Anatomy 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Immunology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
L'invention concerne des polypeptides de gènes humains spécifiques au sein, l'ADN (ARN) les codant et un procédé de production desdits polypeptides par des techniques de recombinaison. Elle porte aussi sur des procédés d'utilisation desdits polynucléotides ou polypeptides en tant que marqueur diagnostique pour le cancer du sein et en tant qu'agent pour déterminer si le cancer du sein a métastasé. Elle se rapporte encore à des anticorps spécifiques aux polypeptides de gènes spécifiques au sein, qui peuvent être utilisés pour cibler des cellules cancéreuses et en tant que partie d'un vaccin contre le cancer du sein, ainsi qu'à des procédés de criblage d'antagonistes du polypeptides et à leurs utilisations thérapeutiques.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/US1995/008295 WO1997002280A1 (fr) | 1995-06-30 | 1995-06-30 | Genes et proteines specifiques au sein |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2225824A1 true CA2225824A1 (fr) | 1997-01-23 |
Family
ID=22249400
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002225824A Abandoned CA2225824A1 (fr) | 1995-06-30 | 1995-06-30 | Genes et proteines specifiques au sein |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP0851869A4 (fr) |
| JP (1) | JPH11509093A (fr) |
| AU (1) | AU3092995A (fr) |
| CA (1) | CA2225824A1 (fr) |
| WO (1) | WO1997002280A1 (fr) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1998033915A1 (fr) * | 1997-02-03 | 1998-08-06 | Human Genome Sciences, Inc. | Gene 1 specifique du cancer du sein |
| WO1998059049A1 (fr) * | 1997-06-20 | 1998-12-30 | Abbott Laboratories | Reactifs et procedes destines a detecter des pathologies mammaires |
| AU8899298A (en) * | 1997-08-06 | 1999-03-01 | Zymogenetics Inc. | Lipocalin homologs |
| GB9719879D0 (en) * | 1997-09-19 | 1997-11-19 | Neuropa Ltd | Protein |
| JP2001523472A (ja) * | 1997-11-18 | 2001-11-27 | アボット・ラボラトリーズ | 乳房の疾患の検出に有用な試薬および方法 |
| US6410507B1 (en) | 1997-12-24 | 2002-06-25 | Corixa Corporation | Compounds for immunotherapy and diagnosis of breast cancer and methods for their use |
| US6379951B1 (en) | 1997-12-24 | 2002-04-30 | Corixa Corporation | Compounds for immunotherapy of breast cancer and methods for their use |
| US6432707B1 (en) | 1997-12-24 | 2002-08-13 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of breast cancer |
| JP2002507387A (ja) * | 1997-12-24 | 2002-03-12 | コリクサ コーポレイション | 乳癌の免疫療法および診断のための化合物ならびにそれらの使用のための方法 |
| US20020045165A1 (en) * | 1997-12-26 | 2002-04-18 | Patricia A. Billing-Medel | Reagents and methods useful for detecting diseases of the breast |
| US6468758B1 (en) | 1998-09-23 | 2002-10-22 | Corixa Corporation | Compositions and methods for ovarian cancer therapy and diagnosis |
| US6969518B2 (en) | 1998-12-28 | 2005-11-29 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of breast cancer |
| US7598226B2 (en) | 1998-12-28 | 2009-10-06 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of breast cancer |
| CA2392510A1 (fr) | 1999-11-30 | 2001-06-07 | Corixa Corporation | Compositions et methodes destinees au traitement et au diagnostic du cancer du sein |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU3665893A (en) * | 1992-02-12 | 1993-09-03 | United States Of America, As Represented By The Secretary, Department Of Health And Human Services, The | Sequences characteristic of human gene transcription product |
-
1995
- 1995-06-30 CA CA002225824A patent/CA2225824A1/fr not_active Abandoned
- 1995-06-30 JP JP9505093A patent/JPH11509093A/ja active Pending
- 1995-06-30 EP EP95926616A patent/EP0851869A4/fr not_active Withdrawn
- 1995-06-30 WO PCT/US1995/008295 patent/WO1997002280A1/fr not_active Application Discontinuation
- 1995-06-30 AU AU30929/95A patent/AU3092995A/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP0851869A1 (fr) | 1998-07-08 |
| WO1997002280A1 (fr) | 1997-01-23 |
| JPH11509093A (ja) | 1999-08-17 |
| AU3092995A (en) | 1997-02-05 |
| EP0851869A4 (fr) | 2002-08-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| FZDE | Discontinued |