CA2214431A1 - Oligonucleotides antisens specifiques du facteur de croissance de l'endothelium vasculaire humain - Google Patents
Oligonucleotides antisens specifiques du facteur de croissance de l'endothelium vasculaire humainInfo
- Publication number
- CA2214431A1 CA2214431A1 CA002214431A CA2214431A CA2214431A1 CA 2214431 A1 CA2214431 A1 CA 2214431A1 CA 002214431 A CA002214431 A CA 002214431A CA 2214431 A CA2214431 A CA 2214431A CA 2214431 A1 CA2214431 A1 CA 2214431A1
- Authority
- CA
- Canada
- Prior art keywords
- antisense oligonucleotides
- human vegf
- specific antisense
- vegf
- disclosed
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
- C12N15/1136—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against growth factors, growth regulators, cytokines, lymphokines or hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/30—Chemical structure
- C12N2310/31—Chemical structure of the backbone
- C12N2310/315—Phosphorothioates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/30—Chemical structure
- C12N2310/32—Chemical structure of the sugar
- C12N2310/321—2'-O-R Modification
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/398,945 US5639872A (en) | 1993-07-27 | 1995-03-02 | Human VEGF-specific oligonucleotides |
US08/569,926 | 1995-12-08 | ||
US08/398,945 | 1995-12-08 | ||
US08/569,926 US5641756A (en) | 1993-07-27 | 1995-12-08 | Modified VEGF oligonucleotides |
PCT/US1996/002840 WO1996027006A2 (fr) | 1995-03-02 | 1996-02-29 | Oligonucleotides antisens specifiques du facteur de croissance de l'endothelium vasculaire humain |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2214431A1 true CA2214431A1 (fr) | 1996-09-06 |
CA2214431C CA2214431C (fr) | 2007-06-05 |
Family
ID=38137576
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002214431A Expired - Fee Related CA2214431C (fr) | 1995-03-02 | 1996-02-29 | Oligonucleotides antisens specifiques du facteur de croissance de l'endothelium vasculaire humain |
Country Status (1)
Country | Link |
---|---|
CA (1) | CA2214431C (fr) |
-
1996
- 1996-02-29 CA CA002214431A patent/CA2214431C/fr not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
CA2214431C (fr) | 2007-06-05 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
MKLA | Lapsed |
Effective date: 20140228 |