CA2211681A1 - Nouveaux derives d'acide pyridonecarboxylique ou de ses sels et agent antibacterien contenant ces derives en tant qu'ingredient actif - Google Patents

Nouveaux derives d'acide pyridonecarboxylique ou de ses sels et agent antibacterien contenant ces derives en tant qu'ingredient actif

Info

Publication number
CA2211681A1
CA2211681A1 CA002211681A CA2211681A CA2211681A1 CA 2211681 A1 CA2211681 A1 CA 2211681A1 CA 002211681 A CA002211681 A CA 002211681A CA 2211681 A CA2211681 A CA 2211681A CA 2211681 A1 CA2211681 A1 CA 2211681A1
Authority
CA
Canada
Prior art keywords
halogeno
same
represents hydrogen
salts
active ingredient
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002211681A
Other languages
English (en)
Other versions
CA2211681C (fr
Inventor
Akira Yazaki
Jiro Yoshida
Yoshiko Niino
Yoshihiro Ohshita
Norihiro Hayashi
Hirotaka Amano
Yuzo Hirao
Yasuhiro Kuramoto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wakunaga Pharmaceutical Co Ltd
Original Assignee
Wakunaga Seiyaku Kabushiki Kaisha
Akira Yazaki
Jiro Yoshida
Yoshiko Niino
Yoshihiro Ohshita
Norihiro Hayashi
Hirotaka Amano
Yuzo Hirao
Yasuhiro Kuramoto
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wakunaga Seiyaku Kabushiki Kaisha, Akira Yazaki, Jiro Yoshida, Yoshiko Niino, Yoshihiro Ohshita, Norihiro Hayashi, Hirotaka Amano, Yuzo Hirao, Yasuhiro Kuramoto filed Critical Wakunaga Seiyaku Kabushiki Kaisha
Publication of CA2211681A1 publication Critical patent/CA2211681A1/fr
Application granted granted Critical
Publication of CA2211681C publication Critical patent/CA2211681C/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Dérivé d'acide pyridonecarboxylique représenté par la formule générale (1) ou un de ses sels et agent antibactérien contenant ledit dérivé, où R<1> représente hydrogène ou un groupe de protection carboxy; R<2> représente nitro ou amino éventuellement substitué; R<3> représente halogéno; R<4> et R<5> peuvent être similaires ou différents et chacun représente hydrogène, halogéno, alkyle inférieur ou alcoxy inférieur; R<6> représente hydrogène, halogeno, hydroxy, alkyle inférieur ou amino; R<7> représente hydrogène ou halogéno; A représente azote ou -CX= (où X représente hydrogène, halogéno, alkyle inférieur ou alcoxy inférieur); Z représente halogéno ou amino cyclique saturé éventuellement substitué.
CA002211681A 1995-01-30 1996-01-26 Nouveaux derives d'acide pyridonecarboxylique ou de ses sels et agent antibacterien contenant ces derives en tant qu'ingredient actif Expired - Fee Related CA2211681C (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP7-12673 1995-01-30
JP1267395 1995-01-30
PCT/JP1996/000152 WO1996023775A1 (fr) 1995-01-30 1996-01-26 Nouveaux derives d'acide pyridonecarboxylique ou de ses sels et agent antibacterien contenant ces derives en tant qu'ingredient actif

Publications (2)

Publication Number Publication Date
CA2211681A1 true CA2211681A1 (fr) 1996-01-30
CA2211681C CA2211681C (fr) 2003-05-13

Family

ID=11811900

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002211681A Expired - Fee Related CA2211681C (fr) 1995-01-30 1996-01-26 Nouveaux derives d'acide pyridonecarboxylique ou de ses sels et agent antibacterien contenant ces derives en tant qu'ingredient actif

Country Status (4)

Country Link
KR (1) KR100499366B1 (fr)
AU (1) AU5260096A (fr)
CA (1) CA2211681C (fr)
WO (1) WO1996023775A1 (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1105715C (zh) * 1995-09-22 2003-04-16 涌永制药株式会社 新型吡啶酮羧酸衍生物或其盐以及以它们为有效成分的抗菌剂
CA2251701A1 (fr) * 1996-04-16 1997-10-23 Yoshiko Niino Nouvelles phenylenediamines et leur procede de preparation
EP0897919B1 (fr) 1996-04-19 2004-06-16 Wakunaga Pharmaceutical Co., Ltd. Nouveaux derives de l'acide pyridonocarboxylique ou des sels de cet acide et agents antibacteriens contenant ces substances en tant que composant actif
MA24500A1 (fr) 1997-03-21 1998-10-01 Lg Life Sciences Ltd Derive du sel d'acide carboxylique de naphthyridine .
US20020032216A1 (en) 1997-03-21 2002-03-14 Lg Chemical Ltd. Salt of naphthyridine carboxylic acid derivative
US7563805B2 (en) 2005-05-19 2009-07-21 Daiichi Pharmaceutical Co., Ltd. Tri-, tetra-substituted-3-aminopyrrolidine derivative
MX2018015462A (es) * 2016-06-15 2019-05-27 Wakunaga Pharma Co Ltd Derivado novedoso del acido piridonacarboxilico o su sal.

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8524662D0 (en) * 1985-10-07 1985-11-13 Fujisawa Pharmaceutical Co Quinolone compounds
JPH0348682A (ja) * 1989-07-14 1991-03-01 Yoshitomi Pharmaceut Ind Ltd ピリドンカルボン酸化合物
JPH0366688A (ja) * 1989-08-03 1991-03-22 Yoshitomi Pharmaceut Ind Ltd １，４―ジヒドロ―４―オキソナフチリジン化合物
DE3934082A1 (de) * 1989-10-12 1991-04-18 Bayer Ag Chinoloncarbonsaeurederivate, verfahren zu ihrer herstellung sowie ihre verwendung als antivirale mittel

Also Published As

Publication number Publication date
KR19980701781A (ko) 1998-06-25
AU5260096A (en) 1996-08-21
KR100499366B1 (ko) 2005-09-08
CA2211681C (fr) 2003-05-13
WO1996023775A1 (fr) 1996-08-08

Similar Documents

Publication Publication Date Title
HK1016602A1 (en) Novel pyridonecarboxylic acid derivatives or their salts, and antibacterial agent comprising the same as the active ingredient
CA2160447A1 (fr) Derives d&#39;amino(thio)ether
EP0513387A4 (en) Active oxygen inhibitor
CA2311742A1 (fr) Nouveaux composes heterocycliques
HK1003708A1 (en) Peripheral vasodilating agent containing n-acylated 4-amino piperidine derivatives as active ingredients
MY105136A (en) Optically active pyridonecarboxylic acid derivatives.
CO5031285A1 (es) Triarilimidazoles
EP1156045A4 (fr) Derives d&#39;amides et compositions de medicaments
MX9606331A (es) Nuevos compuestos, procesos para la preparacion de los mismos y agentes antitumor.
NZ296594A (en) 1-(aminoalkylphenyl)guanidine and isothiourea derivatives
BR9407169A (pt) Derivados de pirazol
ATE170519T1 (de) Stickstoff enthaltende kondensierte heterocylen
AP9801321A0 (en) 2-(4-aryl or heteroaryl-piperazin-1-ylmethyl)-h-indole derivatives.
EP1243268A4 (fr) Composition medicinale
EP0787720A4 (fr) Nouveau derive de pyridone-carboxylate, ou sel de celui-ci, et antibacterien le contenant comme principe actif
IL151035A0 (en) Anti-acid-fast bacterial agents containing pyridonecarboxylic acids as the active ingredient
CA2211681A1 (fr) Nouveaux derives d&#39;acide pyridonecarboxylique ou de ses sels et agent antibacterien contenant ces derives en tant qu&#39;ingredient actif
ES2093091T3 (es) Derivado de glutation.
MY106904A (en) Herbicidal composition.
TW427993B (en) New cephem compounds
EP1134219A4 (fr) Derives d&#39;aminomethylpyrrolidine substitues par des cycloalkyles
TW350840B (en) N-acylpiperazine derivative, antibacterial drug and anti-ulcer drug
EP0842931A4 (fr) Derives d&#39;oxopropionitrile et agents de lutte contre les insectes
EP0657443A4 (fr) Derive de carboxamide a activite optique.
EP0897919A4 (fr) Nouveaux derives de l&#39;acide pyridonocarboxylique ou des sels de cet acide et agents antibacteriens contenant ces substances en tant que composant actif

Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed