CA2207892A1 - Stabilisation des plaquettes sanguines vis-a-vis de l'activation a basse temperature - Google Patents

Stabilisation des plaquettes sanguines vis-a-vis de l'activation a basse temperature

Info

Publication number
CA2207892A1
CA2207892A1 CA002207892A CA2207892A CA2207892A1 CA 2207892 A1 CA2207892 A1 CA 2207892A1 CA 002207892 A CA002207892 A CA 002207892A CA 2207892 A CA2207892 A CA 2207892A CA 2207892 A1 CA2207892 A1 CA 2207892A1
Authority
CA
Canada
Prior art keywords
platelets
antifreeze
thermal hysteresis
proteins
purified
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002207892A
Other languages
English (en)
Inventor
Fern Tablin
John H. Crowe
Ann E. Oliver
Lisa M. Hays
Lois M. Crowe
Robert E. Feeney
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of California
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2207892A1 publication Critical patent/CA2207892A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
    • A01N1/0205—Chemical aspects
    • A01N1/021—Preservation or perfusion media, liquids, solids or gases used in the preservation of cells, tissue, organs or bodily fluids
    • A01N1/0221—Freeze-process protecting agents, i.e. substances protecting cells from effects of the physical process, e.g. cryoprotectants, osmolarity regulators like oncotic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/19—Platelets; Megacaryocytes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Environmental Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Dentistry (AREA)
  • Medicinal Chemistry (AREA)
  • Developmental Biology & Embryology (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Virology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

L'activation spontanée des plaquettes sanguines aux températures de stockage normalement peu élevées peut s'éliminer par le traitement des plaquettes à l'aide de protéines à hystérèse thermique. Les protéines de ce type préférées sont des protéines et des glycoprotéines antigel provenant d'espèces de poissons polaires. Les fractions chromatographiques N~ 2 à 6 des glycoprotéines antigel s'avèrent particulièrement efficaces.
CA002207892A 1995-01-05 1995-12-18 Stabilisation des plaquettes sanguines vis-a-vis de l'activation a basse temperature Abandoned CA2207892A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US36894195A 1995-01-05 1995-01-05
US08/368,941 1995-01-05

Publications (1)

Publication Number Publication Date
CA2207892A1 true CA2207892A1 (fr) 1996-07-11

Family

ID=23453393

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002207892A Abandoned CA2207892A1 (fr) 1995-01-05 1995-12-18 Stabilisation des plaquettes sanguines vis-a-vis de l'activation a basse temperature

Country Status (6)

Country Link
EP (1) EP0871706A4 (fr)
JP (1) JP2001513069A (fr)
CN (1) CN1220696A (fr)
AU (1) AU696094B2 (fr)
CA (1) CA2207892A1 (fr)
WO (1) WO1996021001A1 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102009059274B4 (de) * 2009-12-22 2012-07-19 Max-Joseph Kraus Verfahren zur Messung der Dynamik der Änderungen von Blutplättchen
CN113712023B (zh) * 2021-04-02 2023-07-04 苏州大学 一种血小板的保存方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5358931A (en) * 1990-01-17 1994-10-25 The Regents Of The University Of California Interaction of thermal hysteresis proteins with cells and cell membranes and associated applications

Also Published As

Publication number Publication date
WO1996021001A1 (fr) 1996-07-11
AU4641596A (en) 1996-07-24
JP2001513069A (ja) 2001-08-28
EP0871706A1 (fr) 1998-10-21
CN1220696A (zh) 1999-06-23
AU696094B2 (en) 1998-09-03
EP0871706A4 (fr) 2001-05-02

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued