CA2206211A1 - A controlled release drug suspension delivery device - Google Patents

A controlled release drug suspension delivery device

Info

Publication number
CA2206211A1
CA2206211A1 CA002206211A CA2206211A CA2206211A1 CA 2206211 A1 CA2206211 A1 CA 2206211A1 CA 002206211 A CA002206211 A CA 002206211A CA 2206211 A CA2206211 A CA 2206211A CA 2206211 A1 CA2206211 A1 CA 2206211A1
Authority
CA
Canada
Prior art keywords
delivery device
controlled release
release drug
drug suspension
hydration
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002206211A
Other languages
French (fr)
Other versions
CA2206211C (en
Inventor
Gerald S. Rork
James D. Pipkin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck & Co., Inc.
Gerald S. Rork
James D. Pipkin
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/363,451 external-priority patent/US5582838A/en
Application filed by Merck & Co., Inc., Gerald S. Rork, James D. Pipkin filed Critical Merck & Co., Inc.
Publication of CA2206211A1 publication Critical patent/CA2206211A1/en
Application granted granted Critical
Publication of CA2206211C publication Critical patent/CA2206211C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms

Abstract

A device is disclosed for the controlled delivery of a beneficial agent, the device consisting of (i) a core comprising at least two layers, wherein at least one layer comprises a beneficial agent and a polymer which forms microscopic gel beads upon hydration and at least one layer which comprises a polymer which forms microscopic gel beads upon hydration; and (ii) an impermeable, insoluble coating which adheres to and surrounds the core and contains apertures which provide an area for the hydration and release of the microscopic gel beads.
CA002206211A 1994-12-22 1995-12-18 A controlled release drug suspension delivery device Expired - Fee Related CA2206211C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/363,451 US5582838A (en) 1994-12-22 1994-12-22 Controlled release drug suspension delivery device
US363,451 1994-12-22
PCT/US1995/016530 WO1996019201A1 (en) 1994-12-22 1995-12-18 A controlled release drug suspension delivery device

Publications (2)

Publication Number Publication Date
CA2206211A1 true CA2206211A1 (en) 1996-06-27
CA2206211C CA2206211C (en) 2006-08-08

Family

ID=36791734

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002206211A Expired - Fee Related CA2206211C (en) 1994-12-22 1995-12-18 A controlled release drug suspension delivery device

Country Status (1)

Country Link
CA (1) CA2206211C (en)

Also Published As

Publication number Publication date
CA2206211C (en) 2006-08-08

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Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed